ChemicalBook > CAS DataBase List > 2-Morpholinoethyl isocyanide

2-Morpholinoethyl isocyanide

Product Name
2-Morpholinoethyl isocyanide
CAS No.
78375-48-1
Chemical Name
2-Morpholinoethyl isocyanide
Synonyms
MEI;SKL087;2-Morpholinoethyl is;Morpholino ethyl isocyanide;2-MORPHOLINOETHYL ISOCYANIDE;4-(2-ISOCYANOETHYL)MORPHOLINE;2-Morpholino-ethyl-isocyanate;Morpholinyl-4-ethylisocyanid-2;4-(2-Isocyanatoethyl)morpholine;1-N-(2-ISOCYANOETHYL)-MORPHOLINE
CBNumber
CB0321752
Molecular Formula
C7H12N2O
Formula Weight
140.19
MOL File
78375-48-1.mol
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2-Morpholinoethyl isocyanide Property

Boiling point:
72-73 °C0.7 mm Hg(lit.)
Density 
1.017 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.469
Flash point:
110 ºC
storage temp. 
-20°C
form 
liquid
BRN 
4666990
InChI
InChI=1S/C7H12N2O/c1-8-2-3-9-4-6-10-7-5-9/h2-7H2
InChIKey
MFRZPLYKVDHOSN-UHFFFAOYSA-N
SMILES
C(N1CCOCC1)C[N+]#[C-]
CAS DataBase Reference
78375-48-1(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38
Safety Statements 
26-36/37-45
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
F 
10-21
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
69893
Product name
2-Morpholinoethyl isocyanide
Purity
≥98.0% (GC)
Packaging
10ml
Price
$166
Updated
2025/07/31
Sigma-Aldrich
Product number
69893
Product name
2-Morpholinoethyl isocyanide
Purity
≥98.0% (GC)
Packaging
50ml
Price
$395
Updated
2025/07/31
AK Scientific
Product number
0225AQ
Product name
2-Morpholinoethyl isocyanide
Packaging
50mL
Price
$667
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0009246
Product name
2-MORPHOLINO ETHYL ISOCYANIDE
Purity
95.00%
Packaging
10ML
Price
$1151.19
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0009246
Product name
2-MORPHOLINO ETHYL ISOCYANIDE
Purity
95.00%
Packaging
50ML
Price
$2756.41
Updated
2021/12/16
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2-Morpholinoethyl isocyanide Chemical Properties,Usage,Production

Uses

2-Morpholinoethyl isocyanide can be used for the synthesis of:

  • Nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes.
  • Variety of imidazo[1,2-a]pyridines and α-acylaminoamides by Ugi condensation reaction.
  • 2-Aminobenzoxazoles and 3-aminobenzoxazines having important therapeutic activities.

It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs).

Synthesis

2-Morpholinoethyl isocyanide is prepared by the reaction of 2-morpholinoethylamine with Formic Acid in boiling toluene with a water separator, to yield the formamide which is treated either with Phosgene and Triethylamine in CH2Cl2 or with Phosphorus Oxychloride and Diisopropylamine. The use of diisopropylamine as base is favored as yields are improved, typically to 68%. Trichloroacetic Anhydride has also been used as an alternative for COCl2, giving a yield of 74%.

2-Morpholinoethyl isocyanide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Morpholinoethyl isocyanide manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Morpholinoethyl isocyanide 78375-48-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

78375-48-1, 2-Morpholinoethyl isocyanideRelated Search:

ALLYL ISOCYANATE Chlorosulfonyl isocyanate Propyl isocyanate 4-Fluorophenyl isocyanate tert-Butylisocyanate 1,3,5-Tri-2-propenyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione Ethyl isocyanate Isocyanic acid 3,4-dichlorophenyl ester Phenethyl isocyanate METHYLIDYNETRI-P-PHENYLENE TRIISOCYANATE METHYL ISOCYANATE Phenyl isocyanate morpholine 4-(2-Aminoethyl)morpholine METHYL ISOCYANIDE ETHYL ISOCYANIDE N-MORPHOLINO-2-ISOCYANO-ACETAMIDE 2-Morpholinoethyl isocyanide

  • Morpholino ethyl isocyanide
  • Morpholine, 4-(2-isocyanoethyl)-
  • MEI 2-MORPHOLINOETHYL ISOCYANIDE
  • Morpholinyl-4-ethylisocyanid-2
  • 4-(2-Isocyanatoethyl)morpholine
  • 2-Morpholinoethyl is
  • 2-Morpholinoethyl isocyanide >=98.0% (GC)
  • MEI
  • 2-MORPHOLINOETHYL ISOCYANIDE
  • 1-N-(2-ISOCYANOETHYL)-MORPHOLINE
  • 4-(2-ISOCYANOETHYL)MORPHOLINE
  • 2-Morpholino-ethyl-isocyanate
  • SKL087
  • 78375-48-1
  • Building Blocks
  • Heterocyclic Building Blocks
  • Morpholines
  • Nitro / Nitriles