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4-(2-Aminoethyl)morpholine

Product Name
4-(2-Aminoethyl)morpholine
CAS No.
2038-03-1
Chemical Name
4-(2-Aminoethyl)morpholine
Synonyms
2-morpholinoethan-1-amine;Morpholinoethylamine;4-MORPHOLINEETHANAMINE;2-morpholin-4-ylethanamine;2-(4-Morpholinyl)ethanamine;2-(4-Morpholinyl)ethylamine;RARECHEM AL BW 0412;LM11A 31 Impurity 1;2-Morpholinoethylami;2-MORPHOLINOETHYLAMINE
CBNumber
CB4409865
Molecular Formula
C6H14N2O
Formula Weight
130.19
MOL File
2038-03-1.mol
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4-(2-Aminoethyl)morpholine Property

Melting point:
24 °C
Boiling point:
205 °C(lit.)
Density 
0.992 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.476(lit.)
Flash point:
347 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Chloroform, Methanol
form 
Liquid After Melting
pka
pK1: 4.06(+2);pK2: 9.15(+1) (25°C)
color 
Clear colorless to pale yellow
Water Solubility 
soluble
Sensitive 
Air Sensitive
BRN 
104378
Stability:
Air Sensitive
InChIKey
RWIVICVCHVMHMU-UHFFFAOYSA-N
CAS DataBase Reference
2038-03-1(CAS DataBase Reference)
NIST Chemistry Reference
4-Morpholineethanamine(2038-03-1)
EPA Substance Registry System
4-Morpholineethanamine (2038-03-1)
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Safety

Hazard Codes 
C,T
Risk Statements 
22-34-43-24-40-23/24/25
Safety Statements 
26-36/37/39-45-22
RIDADR 
UN 2735 8/PG 2
WGK Germany 
2
RTECS 
QD7350000
Hazard Note 
Toxic
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29349990
Toxicity
guinea pig,LD50,skin,300uL/kg (0.3mL/kg),Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A55004
Product name
4-(2-Aminoethyl)morpholine
Purity
99%
Packaging
5G
Price
$54.5
Updated
2024/03/01
Sigma-Aldrich
Product number
A55004
Product name
4-(2-Aminoethyl)morpholine
Purity
99%
Packaging
25G
Price
$85.7
Updated
2024/03/01
Sigma-Aldrich
Product number
A55004
Product name
4-(2-Aminoethyl)morpholine
Purity
99%
Packaging
100G
Price
$191
Updated
2024/03/01
TCI Chemical
Product number
A0883
Product name
4-(2-Aminoethyl)morpholine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
A0883
Product name
4-(2-Aminoethyl)morpholine
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$93
Updated
2024/03/01
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4-(2-Aminoethyl)morpholine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to pale yellow liq. after melting

Uses

4-(2-Aminoethyl)morpholine is used as a ligand and reacts with nickel(II) nitrite to form trans-bis[4-(2-aminoethyl)morpholine]dinitronickel(II).

Uses

4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:

  • Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
  • Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
  • Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
  • It is also used as a precursor to synthesize a variety of antimicrobial agents.

Definition

ChEBI: 4-2-Aminoethyl-morpholine is a member of morpholines.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 34, p. 1805, 1991 DOI: 10.1021/jm00110a008

4-(2-Aminoethyl)morpholine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-Aminoethyl)morpholine Suppliers

Yangzhou Prince Chemical Co., Ltd
Tel
0514-84248359 13328140016
Email
sales@princechem.com
Country
China
ProdList
99
Advantage
58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83946278 13820503911
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
982
Advantage
68
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 4-(2-Aminoethyl)morpholine manufacturers

Career Henan Chemical Co
Product
4-(2-Aminoethyl)morpholine 2038-03-1
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22

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