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4-(2-Aminoethyl)morpholine

Product Name
4-(2-Aminoethyl)morpholine
CAS No.
2038-03-1
Chemical Name
4-(2-Aminoethyl)morpholine
Synonyms
2-morpholinoethan-1-amine;Morpholinoethylamine;4-MORPHOLINEETHANAMINE;2-morpholin-4-ylethanamine;2-(4-Morpholinyl)ethanamine;2-(4-Morpholinyl)ethylamine;RARECHEM AL BW 0412;LM11A 31 Impurity 1;2-Morpholinoethylami;2-MORPHOLINOETHYLAMINE
CBNumber
CB4409865
Molecular Formula
C6H14N2O
Formula Weight
130.19
MOL File
2038-03-1.mol
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4-(2-Aminoethyl)morpholine Property

Melting point:
24 °C
Boiling point:
205 °C(lit.)
Density 
0.992 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.476(lit.)
Flash point:
347 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Chloroform, Methanol
form 
Liquid After Melting
pka
pK1: 4.06(+2);pK2: 9.15(+1) (25°C)
color 
Clear colorless to pale yellow
Water Solubility 
soluble
Sensitive 
Air Sensitive
BRN 
104378
Stability:
Air Sensitive
InChIKey
RWIVICVCHVMHMU-UHFFFAOYSA-N
CAS DataBase Reference
2038-03-1(CAS DataBase Reference)
NIST Chemistry Reference
4-Morpholineethanamine(2038-03-1)
EPA Substance Registry System
4-Morpholineethanamine (2038-03-1)
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Safety

Hazard Codes 
C,T
Risk Statements 
22-34-43-24-40-23/24/25
Safety Statements 
26-36/37/39-45-22
RIDADR 
UN 2735 8/PG 2
WGK Germany 
2
RTECS 
QD7350000
Hazard Note 
Toxic
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29349990
Toxicity
guinea pig,LD50,skin,300uL/kg (0.3mL/kg),Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 269, 1944.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A55004
Product name
4-(2-Aminoethyl)morpholine
Purity
99%
Packaging
5G
Price
$54.5
Updated
2024/03/01
Sigma-Aldrich
Product number
A55004
Product name
4-(2-Aminoethyl)morpholine
Purity
99%
Packaging
25G
Price
$85.7
Updated
2024/03/01
Sigma-Aldrich
Product number
A55004
Product name
4-(2-Aminoethyl)morpholine
Purity
99%
Packaging
100G
Price
$191
Updated
2024/03/01
TCI Chemical
Product number
A0883
Product name
4-(2-Aminoethyl)morpholine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
A0883
Product name
4-(2-Aminoethyl)morpholine
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$93
Updated
2024/03/01
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4-(2-Aminoethyl)morpholine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to pale yellow liq. after melting

Uses

4-(2-Aminoethyl)morpholine is used as a ligand and reacts with nickel(II) nitrite to form trans-bis[4-(2-aminoethyl)morpholine]dinitronickel(II).

Uses

4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:

  • Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
  • Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
  • Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
  • It is also used as a precursor to synthesize a variety of antimicrobial agents.

Definition

ChEBI: 4-2-Aminoethyl-morpholine is a member of morpholines.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 34, p. 1805, 1991 DOI: 10.1021/jm00110a008

4-(2-Aminoethyl)morpholine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-Aminoethyl)morpholine Suppliers

TCI Chemicals (India) Pvt. Ltd.
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Pharmaffiliates Analytics and Synthetics P. Ltd
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A.J Chemicals
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sales@ajchem.in
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OCEAN TRADING CORPORATION
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otcchem@otcchem.com
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View Lastest Price from 4-(2-Aminoethyl)morpholine manufacturers

Career Henan Chemical Co
Product
4-(2-Aminoethyl)morpholine 2038-03-1
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22

2038-03-1, 4-(2-Aminoethyl)morpholineRelated Search:


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