Description References
ChemicalBook > CAS DataBase List > Dimethomorph

Dimethomorph

Description References
Product Name
Dimethomorph
CAS No.
110488-70-5
Chemical Name
Dimethomorph
Synonyms
4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)-morpholin (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)morpholine;dimethomoph;Z-DIMETHOMORPH;3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-Morpholinoprop-2-en-1-one;3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-(4-Morpholinyl)-2-propen-1-one;FORUM;ACROBAT;CME 151;AcrobatWP;Festival C
CBNumber
CB9774944
Molecular Formula
C21H22ClNO4
Formula Weight
387.86
MOL File
110488-70-5.mol
More
Less

Dimethomorph Property

Melting point:
125-149°C
Boiling point:
584.9±50.0 °C(Predicted)
Density 
1.231±0.06 g/cm3(Predicted)
vapor pressure 
1 x 10-6 Pa (25 °C)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform: Soluble,Methanol: Soluble
Water Solubility 
50 mg l-1 (20-23 °C)
pka
-1.19±0.20(Predicted)
form 
Solid
color 
White to off-white
Merck 
13,3248
BRN 
8794474
LogP
2.680
EPA Substance Registry System
Dimethomorph (110488-70-5)
More
Less

Safety

Hazard Codes 
N
Risk Statements 
51/53
Safety Statements 
61
RIDADR 
UN3077 9/PG 3
WGK Germany 
2
RTECS 
QE0478300
Hazardous Substances Data
110488-70-5(Hazardous Substances Data)
Toxicity
LD50 in rats (mg/kg): 321 i.p.; 3900 orally; >5000 dermally; LC50 (4-hr inhalation): >4.2 mg/ml (Veenstra, Owen)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
46027
Product name
Dimethomorph
Purity
mixture of E + Z isomers
Packaging
100mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
24247
Product name
Dimethomorph
Purity
≥95%
Packaging
50mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
24247
Product name
Dimethomorph
Purity
≥95%
Packaging
100mg
Price
$74
Updated
2024/03/01
TRC
Product number
D460530
Product name
Dimethomorph
Packaging
5g
Price
$590
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0012814
Product name
4-[3-(4-CHLOROPHENYL)-3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]-MORPHOLINE
Purity
95.00%
Packaging
1G
Price
$716.1
Updated
2021/12/16
More
Less

Dimethomorph Chemical Properties,Usage,Production

Description

Dimethomorph is a cinnamic acid derivative and a member of the morpholine chemical family. Dimethomorph is a mixture of E- and Z-isomers in the ratio of about 1:1 and only the Z-isomer has the fungicidal activity. It fungicidal activity works by the inhibition of sterol (ergosterol) synthesis.
Dimethomorph is a systemic fungicide to protect against various fungal pathogens in vines and other crops. Dimethomorph is used to against downy mildews, late blights, anthracnose, septoria leaf spot, crown rot, and root rot for curbubits, grapevines, head lettuce, onions, potatoes, tomatoes, and fruit including blackberries, raspberries, strawberries.

References

[1] http://www.fao.org
[2] http://pmep.cce.cornell.edu
[3] http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/245.htm

Description

Dimethomorph is a morpholine fungicide that inhibits fungal cell wall formation. It inhibits mycelial growth of the oomycete fungi P. citrophthora, P. parasitica, P. capsici, and P. infestans (EC50s = 0.14, 0.38, <0.1, and 0.16-0.3 μg/ml, respectively) but is less active against the green algae species C. vulgaris or S. obliquus in vitro (EC50s = 47.46 and 44.87 μg/ml, respectively). It inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC20s = 0.263 and 38.5 μM, respectively). It is not toxic to rats (LD50 = 3,900 mg/kg) or goldfish (C. auratus; LC50 = >32 μg/ml).

Chemical Properties

Off-White Solid

Uses

Agricultural fungicide.

Uses

Dimethomorph is a systemic fungicide which exhibits protectant, curative and antisporulant activities. It is active against fungal diseases such as leaf blight, downy mildew, damping off and foot-rot caused by Phytophthora spp. in/on grapes, potatoes and tomatoes.

Definition

ChEBI: A mixture of (E)- and (Z)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the Z isomer has fungicidal activity.

Agricultural Uses

Fungicide: A systemic fungicide that protects crops from mold. It also kills mold and prevents their spread; controls late blight on tomatoes; and is used as a wood preservative to control downey mildew.

Trade name

ACROBAT® WP; FORUM DC®, [manco- zeb + dimethomorph]; CME 151®; STATURE®

Metabolic pathway

Limited data are available in the open literature. Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1994). Dimethomorph is a (1:l) mixture of the E- and Z-isomers. The Z-isomer has been shown to have all the intrinsic biological activities. The isomerisation of the E- and Z-isomers was observed when resolved isomers were exposed to UV light. Dimethomorph undergoes extensive degradation and metabolism in soil, plants and animals. The major metabolic pathway is the O-demethylation of one of the phenolic methoxy moieties to the corresponding phenols and conjugates. Other metabolic reactions include the oxidation of one of the CH2 moieties of the morpholine ring and the cleavage/opening of the morpholine ring (Scheme 1).

Degradation

Dimethomorph (1) is hydrolytically stable with no observable degradation in pH 4-9 buffered solutions at 70-90 °C for up to 10 weeks.
Degradation occurred when dimethomorph in pH 5 buffer solution was irradiated under Hanau Suntest apparatus (<290 nm) at 25 °C. The calculated aqueous photolytic degradation half-life (DT50) was ca. 25-28 days of continuous irradiation, No sigruficant degradation product (>7% of the applied radioactivity) was identified.

Dimethomorph Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Dimethomorph Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8844
Advantage
52
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
VOT INTERNATIONAL BUSINESS CO.,LTD
Tel
0536-2456718
Fax
0536-8231856
Country
China
ProdList
226
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
More
Less

View Lastest Price from Dimethomorph manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Dimethomorph 110488-70-5
Price
US $58.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-22
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Dimethomorph 110488-70-5
Price
US $1000.00-400.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-12
Hebei Dangtong Import and export Co LTD
Product
Dimethomorph 110488-70-5
Price
US $10900.00-10000.00/Tons
Min. Order
1Tons
Purity
99.99%
Supply Ability
200Tons
Release date
2023-04-11

110488-70-5, DimethomorphRelated Search:


  • 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)-morpholin (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)morpholine
  • Dimethomorph W.P.(50%)
  • Festival C
  • Dimethomorph 100mg [110488-70-5]
  • 3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-(4-Morpholinyl)-2-propen-1-one
  • 3-(4-Chlorophenyl)-3-(3,4-diMethoxyphenyl)-1-Morpholinoprop-2-en-1-one
  • Dimethomorph 0
  • Factory hot sell Dimethomorph CAS:110488-70-5 with best price
  • Dimethomorph(mixture of E + Z isomers)
  • Acrobat(TM)
  • Dimethomorph +Ametoctradin
  • Dimethomorph in Methanol
  • Dimethomorph Solution in Acetonitrile
  • (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl]morpholine
  • (e,z)-4-[3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine
  • 4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)-morpholin
  • AcrobatWP
  • ACROBAT
  • Morpholine, 4-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl-
  • dimethomorph (bsi, draft-iso)
  • (E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholinoprop-2-en-1-one
  • Dimethomorph Solution, 1000ppm
  • 4-[3-(4-CHLOROPHENYL)-3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]-MORPHOLINE
  • 4-[3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl]morpholine
  • CME 151
  • DIMETHOMORPH
  • FORUM
  • Z-DIMETHOMORPH
  • Dimethomorph{(E,Z)-4-[3-(4-Chlorophenyl)-3-(3,4-Dimethoxphenyl)Acryloy]Morpholine
  • Dimethoroph
  • DIMETHOMORPH MIXTURE OF E + Z ISOMERS, P
  • dimethomoph
  • DimethomorphSolution,1000mg/L,1ml
  • DimethomorphSolution,100mg/L,5x1ml
  • DimethomorphSolution,100mg/L,1ml
  • Dimethomorph (E, Z)@1000 μg/mL in Acetonitrile
  • Dimethomorph @100 μg/mL in MeOH
  • Dimethomorph 50%WP Chemical Fungicides Products 110488-70-5
  • White powder Chemical Pesticide Dimethomorph Fungicide 50%WP 110488-70-5
  • imethomorph
  • Dimethomorph (0.1 mg/mL in Acetonitrile)
  • Acroyl]-Dimethomorph 13C
  • 2-Propen-1-one, 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(4-morpholinyl)-
  • Enoylmorpholine technical
  • Dimethomorph in Acetone
  • C12710000 Dimethomorph
  • Dimethomorph 10 μg/ml Ethyl acetate
  • Dimethomorph 10.0 μg/ml Acetonitrile
  • Dimethomorph 100 μg/ml Ethyl acetate
  • L12710000ALDimethomorph 10μg/mLin Acetonitri
  • L12710000CY Dimethomorph 10μg/mLin Cyclohexan
  • Dimethomorph in Acetonitrile
  • 110488-70-5
  • C21H22ClNO4
  • Alpha sort
  • D
  • DAlphabetic
  • DID - DINPesticides