Description Preparation Reference
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1,1-Dimethoxyethane

Description Preparation Reference
Product Name
1,1-Dimethoxyethane
CAS No.
534-15-6
Chemical Name
1,1-Dimethoxyethane
Synonyms
DIMETHYL ACETAL;ACETALDEHYDE DIMETHYL ACETAL;Ethane,1,1-dimethoxy-;FEMA 3426;methylformyl;CH3CH(OCH3)2;dimethylaldehyde;Dimethyl aldehyde;AKOS BBS-00004400;1,1-dimethoxy-ethan
CBNumber
CB6853747
Molecular Formula
C4H10O2
Formula Weight
90.12
MOL File
534-15-6.mol
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1,1-Dimethoxyethane Property

Melting point:
-113 °C
Boiling point:
64 °C(lit.)
Density 
0.852 g/mL at 25 °C(lit.)
vapor density 
3.1 (vs air)
vapor pressure 
200 hPa (20 °C)
FEMA 
3426 | 1,1-DIMETHOXYETHANE
refractive index 
n20/D 1.367(lit.)
Flash point:
1 °F
storage temp. 
Store below +30°C.
solubility 
Chloroform (Sparingly)
form 
Oil
color 
Colourless
Odor
at 1.00 % in propylene glycol. sharp sweet alcohol ether green new mown hay
Odor Type
ethereal
Water Solubility 
Soluble
Sensitive 
Moisture Sensitive
Merck 
14,3226
JECFA Number
940
BRN 
1697039
Dielectric constant
3.4900000000000002
LogP
0.63 at 25℃
CAS DataBase Reference
534-15-6(CAS DataBase Reference)
NIST Chemistry Reference
Ethane, 1,1-dimethoxy-(534-15-6)
EPA Substance Registry System
1,1-Dimethoxyethane (534-15-6)
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Safety

Hazard Codes 
F
Risk Statements 
11
Safety Statements 
9-16-33
RIDADR 
UN 2377 3/PG 2
WGK Germany 
2
RTECS 
AB2825000
10-21
TSCA 
Yes
HS Code 
2911 00 00
HazardClass 
3
PackingGroup 
II
Hazardous Substances Data
534-15-6(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 6.5 g/kg; LC (in air) in rats: 16000 ppm (Smyth)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.20002
Product name
Acetaldehyde dimethyl acetal
Purity
for synthesis
Packaging
25mL
Price
$54.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20002
Product name
Acetaldehyde dimethyl acetal
Purity
for synthesis
Packaging
100mL
Price
$94.3
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20002
Product name
Acetaldehyde dimethyl acetal
Purity
for synthesis
Packaging
10L
Price
$1580
Updated
2024/03/01
Sigma-Aldrich
Product number
385395
Product name
Acetaldehyde dimethyl acetal
Purity
95%
Packaging
25ml
Price
$96.1
Updated
2024/03/01
Sigma-Aldrich
Product number
385395
Product name
Acetaldehyde dimethyl acetal
Purity
95%
Packaging
100ml
Price
$212
Updated
2024/03/01
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1,1-Dimethoxyethane Chemical Properties,Usage,Production

Description

1,1-Dimethoxyethane is an aliphatic hydrocarbon which is found in figs, leek, and black tea. It gives a sharp ethereal, fruity and green note. It is used as a flavoring agent in food. 1,1-Dimethoxyethane is also used as a reagent for the diol protection and condensation reactions.

Preparation

To a flask equipped with a mechanical stirrer, condenser, and gas addition tube and containing 10 gm of a 6 3% solution of boron trifluoride in methanol is added 1.0 gm of mercuric oxide and 200 gm (6.25 moles) of methanol. Then 70 gm (3.13 moles) of acetylene is added with vigorous stirring at room temperature. After the reaction the catalyst is neutralized with aqueous potassium carbonate, the product is extracted into ether, dried, and distilled to afford 104 gm (37%), b.p. 64°-65°C.

Reference

Evaluation of Certain Food Additives and Contaminants: Fifty-seventh report of the Joint FAO/WHO Expert Committee on Food Additives, 2001, ISBN 92-4-120909-7
M. J. Taschner, Encyclopedia of Reagents for Organic Synthesis, 2001, ISBN 9780471936237

Chemical Properties

1,1-Dimethoxybenzene is a clear colorless liquid with a sharp, sweet, alcohol, ether, green, new-mown-hay odor. It can miscible with water, alcohol, ether and chloroform.

Occurrence

Reported found in raspberry, blackberry, strawberry, peas, fresh figs, hop oil, coffee, cognac, white wine and tea.

Uses

1,1-Dimethoxyethane is used as a reagent in the synthesis of tricyclic and tetracyclic 1,5-benzodiazepine derivatives as nevirapine analogues. It can also be used as Mering's mixture which is 2 vol dimethylacetal and 1 vol chloroform.

Uses

Acetaldehyde dimethyl acetal may be used in the preparation of glucoside derivatives of steganol. It may be used as polymer solvent for the encapsulation of water-soluble model protein, bovine serum albumin into biodegradable poly(D,L-lactic acid.

Definition

ChEBI: 1,1-dimethoxyethane is an acetal that is dimethoxymethane substituted by a methyl group at position 1. It has a role as a flavouring agent and a plant metabolite. It is an acetal and a diether. It is functionally related to a dimethoxymethane.

Preparation

From acetaldehyde and methanol.

General Description

A liquid with a sharp odor. Less dense than water. Flash point between 0-73°F. Mildly toxic by ingestion and inhalation. Severely irritates the skin and eyes. Used to make other chemicals.

Air & Water Reactions

Highly flammable. May form unstable peroxides when exposed to oxygen. These products can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Slightly soluble in water.

Reactivity Profile

1,1-Dimethoxyethane may react violently with strong oxidizing agents. Can act as a weak base to form salts with strong acids and addition complexes with Lewis acids. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

Health Hazard

Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mildly toxic by inhalation, ingestion, and skin contact. A skin and eye irritant. A very dangerous fire hazard when exposed to heat, flame, or oxiduzers. When exposed to heat or flame it can react vigorously with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.

Purification Methods

Distil the dimethyl acetal through a fractionating column and fraction boiling at 63.8o/751mm is collected. It forms an azeotrope with MeOH. Alternatively purify it as for acetal above. It has been purified by GLC. [Beilstein 1 IV 3103.]

1,1-Dimethoxyethane Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1-Dimethoxyethane Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
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View Lastest Price from 1,1-Dimethoxyethane manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1,1-Dimethoxyethane 534-15-6
Price
US $0.00-0.00/Kg
Min. Order
100G
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-17

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