Uses
ChemicalBook > CAS DataBase List > (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

Uses
Product Name
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
CAS No.
14347-78-5
Chemical Name
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Synonyms
(R)-(-)-1,2-O-ISOPROPYLIDENEGLYCEROL;(R)-(-)-SOLKETAL;R-Glycerol;ane-4-methanoL;R-(-)-Sollketal;(R)-(-) -acetone;R-GLYCEROL ACETONIDE;L-Glycerol-acetonide;(R)-(-)-2,2-Dimethyl-1;Glycerol Formal Impurity 8
CBNumber
CB6184467
Molecular Formula
C6H12O3
Formula Weight
132.16
MOL File
14347-78-5.mol
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(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Property

alpha 
-13.7 º (neat)
Boiling point:
72-73 °C/8 mmHg (lit.)
Density 
1.062 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.434
Flash point:
176 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
pka
14.20±0.10(Predicted)
color 
Clear colorless to light yellow
Specific Gravity
1.062
optical activity
[α]20/D 13.7°, neat
Water Solubility 
miscible
Merck 
14,5213
BRN 
80117
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
RNVYQYLELCKWAN-RXMQYKEDSA-N
CAS DataBase Reference
14347-78-5(CAS DataBase Reference)
NIST Chemistry Reference
D-Acetone glycerol(14347-78-5)
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
RTECS 
JI0400000
F 
10
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
241806
Product name
(R)-(?)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Purity
98%
Packaging
1g
Price
$36.2
Updated
2025/07/31
Sigma-Aldrich
Product number
241806
Product name
(R)-(?)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Purity
98%
Packaging
5g
Price
$75.9
Updated
2025/07/31
TCI Chemical
Product number
D1705
Product name
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Purity
>97.0%(GC)
Packaging
1g
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
D1705
Product name
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Purity
>97.0%(GC)
Packaging
5g
Price
$39
Updated
2025/07/31
TCI Chemical
Product number
D1705
Product name
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Purity
>97.0%(GC)
Packaging
25g
Price
$137
Updated
2025/07/31
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(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Chemical Properties,Usage,Production

Uses

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a MEK inhibitor with antitumor activity.

Chemical Properties

colourless liquid

Uses

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol may be used to prepare:

  • (R)-2,2-Dimethyl-4-benzoxymethyl-1,3-dioxolane.
  • ((S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate)-1,3-dioxolane.
  • (S)-Glyceraldehyde acetonide.
  • Tetraoxaspiroundecanes, diglycerides, glyceryl phosphates, and spiropyrans.

Uses

A MEK inhibitor

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Preparation Products And Raw materials

Raw materials

L(+)-Diethyl L-tartrate p-Toluenesulfonic acid Ethanol 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Acetone Tetrabutylammonium bromide Sodium borohydride Tetrahydrofuran (2S,3S)(-)-Dihydroxybutane-1,4-dioic acid diethyl ester Ethyl acetate Acetic acid Sodium periodate

Preparation Products

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(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Suppliers

Americas 1 Austria 1 Belgium 4 Canada 2 China 275 China Hong Kong 1 Europe 2 France 2 Germany 9 India 12 Ireland 1 Japan 7 Slovakia 2 South Korea 2 Switzerland 8 The Netherlands 1 United Kingdom 15 United States 47 Global 392
Suzhou Highfine Biotech Co., Ltd
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0512-69209928 18796809688
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zhouyingxiang@highfine.com
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China
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MINKESH (SHANGHAI) CO., LTD.
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+86-021-20980300 +86-13167252998
Fax
021-20983811
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sales@minkesh.com
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China
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0537-4531868 18553729317
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0531-84212239; 18615526239
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13816253073
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Shandong longyue of chemical co., LTD
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15318857512
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Jinan Dexinjia Bio&Tech Co., Ltd
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0531-82371986 15269101859
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0531-82375893
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3276840968@qq.com
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Jinan Hanyu Chemical Co., Ltd
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0531-69954981 15666777973
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sales@hanyuchem.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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View Lastest Price from (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol 14347-78-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
(R)-(-)-Solketal 14347-78-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Hebei Chuanghai Biotechnology Co,.LTD
Product
(R) - (-) -2, 2-Dimethyl-1, 3-Dioxolane-4-Methanol 14347-78-5
Price
US $10.70/KG
Min. Order
10KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21

14347-78-5, (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanolRelated Search:

Hydroxyacetone Glycerol Dimethyl ether Dimethyl carbonate Dimethyl fumarate Dacthal Methanol Dimethyl sulfoxide 1,3-Dioxan-5-ol N,N-Dimethylformamide Dimethyl disulfide Diacetone Alcohol Dimethyl sulfate ETHANE Nitroglycerin Diacetonefructose 2,2-Dimethyl-1,3-dioxolane-4-methanol 5'-ACETYL-2',3'-ISOPROPYLIDENEADENOSINE

  • L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL
  • L-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL
  • L-(-)-1,2-ISOPROPYLIDENEGLYCEROL
  • 2,3-ISOPROPYLIDENE-SN-GLYCEROL
  • 2,3-O-ISOPROPYLIDENE-L-GLYCEROL
  • (-)-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL
  • R-GLYCEROL ACETONIDE
  • R-(-)-2,3-O-ISOPROPYLIDENEGLYCEROL
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol, 95+%
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol, L-α,β-Isopropylideneglycerol
  • 2,3-Isopropylidene-sn-glycerol, L-α,β-Isopropylideneglycerol, L-2,3-O-isopropylidene-sn-glycerol
  • (2R)-1-O,2-O-Isopropylideneglycerol
  • (4R)-2,2-Dimethyl-1,3-dioxolane-4α-methanol
  • (4R)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
  • (-)-2,3-O-ISOPROPYLIDENE-SN-GLYCE
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol,98%
  • R-(-)-Sollketal
  • (R)-(-)-2,2-Dimethyl-1,3-dioxlane-4-methanol
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol 98%
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol (R)-(-)-Sollketal
  • (R)-2,3-ISOPROPYLIDENE GLYCEROL
  • R-(-)-2,2-DIMETHYL-1,3-DIOXOLAN-4-METHANOL
  • ((R)-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL
  • R-(-)-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL
  • (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL
  • (R)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL
  • (R)-(-)-2,2-DIMETHYL-4-HYDROXYMETHYL-1,3-DIOXOLANE
  • (R)-2,2-DIMETHYL 4-HYDROXYMETHYL-1,3-DIOXOLANE
  • (R)-(-)-1,2-O-ISOPROPYLIDENEGLYCEROL
  • (R)-(-)-SOLKETAL
  • (R)-2,2-dimethyl-1,3-dioxalone-4-methanol
  • L-Glycerol-acetonide
  • (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLANE-4-MET HANOL, 98% (99% EE/GLC)
  • (R)-(-)-1,2-Isopropylideneglycerol
  • Glycerol acetonide((R)-1,2-O-Isopropylideneglycerol)
  • R-Glycerol
  • 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, (4R)-
  • (R)-(-)-1,2-O-ISOPROPYLIDENEGLYCEROL (GLYCEROL ACETONIDE)
  • (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL ((R)-(-)-SOLKETAL)
  • L-a,b-Isopropylideneglycerol
  • SOLKETAL A.K.A. (R)-O-ISOPROPYLIDENE GLYCEROL
  • ISOPROPYLIDENEGLYCEROL 23RO
  • (R)-(-)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL 97+%
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol (-)-2,3-O-Isopropylidene-sn-glycerol
  • [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol
  • ane-4-methanoL
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol, 98%, ee: 98%
  • (R)-(-)-1,2-O-Isopropylideneglycerol 97%
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol&gt
  • (R) - (-) - Glycerol Acetone
  • (R)-(-)-2,2-Dimethyl-1
  • (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol 2,3-Isopropylidene-sn-glycerol
  • L-α,β-Isopropylideneglycerol
  • R-(-)-Glycerol Acetone Acetal
  • (R)-2,2-Dimethyl-1,3-dioxolane-4-methanol / (R)-1,2-Isopropylideneglycerol
  • R-(-)-(2,2-dimethyl-1,3-dioxolan-4-yl)methnaol
  • (R)-(-) -acetone
  • Glycerol Formal Impurity 8