ChemicalBook > CAS DataBase List > Dimethyl ether

Dimethyl ether

Product Name
Dimethyl ether
CAS No.
115-10-6
Chemical Name
Dimethyl ether
Synonyms
RE170;dymela;RE-170;(CH3)2O;Dymel A;demeond;woodether;Wood ether;FK-506 3'ether,methyl
CBNumber
CB8765901
Molecular Formula
C2H6O
Formula Weight
46.07
MOL File
115-10-6.mol
More
Less

Dimethyl ether Property

Melting point:
−141 °C(lit.)
Boiling point:
−24.8 °C(lit.)
Density 
1.617
vapor density 
1.62 (vs air)
vapor pressure 
>760 mm Hg ( 25 °C)
refractive index 
1.2984
Flash point:
-41°C
solubility 
Soluble in acetone, chloroform, ethanol (95%), ether, and 1 in 3 parts of water. Dimethyl ether is generally miscible with water, nonpolar materials, and some semipolar materials. For pharmaceutical aerosols, ethanol (95%) is the most useful cosolvent. Glycols, oils, and other similar materials exhibit varying degrees of miscibility with dimethyl ether.
Odor
Chloroform-like; sweet.
Odor Threshold
500ppm
explosive limit
27%
Water Solubility 
soluble
Merck 
6071
BRN 
1730743
Stability:
Stable. Extremely flammable. Note low flash point. May form explosive mixtures with air. May form peroxides during prolonged storage.
CAS DataBase Reference
115-10-6(CAS DataBase Reference)
NIST Chemistry Reference
Dimethyl ether(115-10-6)
EPA Substance Registry System
Dimethyl ether (115-10-6)
More
Less

Safety

Hazard Codes 
F+
Risk Statements 
12
Safety Statements 
9-16-33
RIDADR 
UN 1033 2.1
WGK Germany 
1
RTECS 
PM4780000
4.5-31
Autoignition Temperature
662 °F
HazardClass 
2.1
Hazardous Substances Data
115-10-6(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H220Extremely flammable gas

H280Contains gas under pressure; may explode if heated

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P377Leaking gas fire: Do not extinguish, unless leak can be stopped safely.

P381Eliminate all ignition sources if safe to do so.

P410+P403Protect from sunlight. Store in a well-ventilated place.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
295299
Product name
Dimethyl ether
Purity
≥99%
Packaging
100g
Price
$191
Updated
2021/03/22
Sigma-Aldrich
Product number
295299
Product name
Dimethyl ether
Purity
≥99%
Packaging
1kg
Price
$446
Updated
2021/03/22
Sigma-Aldrich
Product number
295299
Product name
Dimethyl ether
Purity
≥99%
Packaging
400g
Price
$255
Updated
2021/03/22
More
Less

Dimethyl ether Chemical Properties,Usage,Production

Chemical Properties

Dimethyl ether is a liquefied gas and exists as a liquid at room temperature when contained under its own vapor pressure, or as a gas when exposed to room temperature and pressure.
It is a clear, colorless, virtually odorless liquid. In high concentrations, the gas has a faint ether-like odor.

Uses

Methyl ether is used as an aerosol propellantand in refrigeration.

Uses

Aerosol propellant; alternative diesel fuel; chemical intermediate.

Uses

Dimethyl ether is used as a solvent in aerosol formulations.

Definition

ChEBI: An ether in which the oxygen atom is connected to two methyl groups.

Production Methods

Dimethyl ether is prepared by the reaction of bituminous or lignite coals with steam in the presence of a finely divided nickel catalyst. This reaction produces formaldehyde, which is then reduced to methanol and dimethyl ether. Dimethyl ether may also be prepared by the dehydration of methanol.

General Description

Dimethyl ether is a colorless gas with a faint ethereal odor. Dimethyl ether is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Dimethyl ether is easily ignited. Its vapors are heavier than air. Any leak can be either liquid or vapor. Dimethyl ether can asphyxiate by the displacement of air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket.

Air & Water Reactions

Highly flammable. Upon standing and exposure to air (oxygen) tendency to form explosive peroxides. When ethers containing peroxides are heated (distilled) they can detonate [Lewis, 3rd ed., 1993, p. 854].

Reactivity Profile

Dimethyl ether is a colorless, highly flammable gas (b. p. -24° C), slightly toxic. Very dangerous fire and explosion hazard when exposed to flame, sparks, heat or strong oxidizers. Violent reaction with aluminum hydride, lithium aluminum hydride. Upon standing and exposure to air (oxygen) tendency to form explosive peroxides. When ethers containing peroxides are heated (distilled) they can detonate [Lewis, 3rd ed., 1993, p. 854].

Health Hazard

Methyl ether produced low inhalation toxicity in rats. Caprino and Togna (1975)reported a 30-minute LC50 value of 396 ppmfor rats. In lethal doses it caused sedation,a gradual depression of motor activity, lossof the sighting reflex, hypopnea, coma, anddeath in mice. Exposure to a 40% mixtureof methyl ether in air resulted in an initialslight increase in heart rate in rabbits, whichwas followed by depression of arterial bloodpressure. Death occurred in 45 minutes. Thearterial and venous partial oxygen pressurewas found to decrease while the venous CO2pressure and the blood pH increased
Reuzel et al. (1981) reported that sub chronic inhalation of methyl ether in ratsdid not cause significant adverse effects.No noticeable effect on organ and bodyweights and no treatment-related changeswere observed. In humans, adverse healtheffect from inhalation of this compoundshould be minimal. However, inhalation ofexcessive quantities can produce intoxicationand loss of consciousness.

Fire Hazard

Behavior in Fire: Containers may explode. Vapors are heavier than air and may travel long distance to a source of ignition and flash back.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Pharmaceutical Applications

Dimethyl ether may be used as an aerosol propellant for topical aerosol formulations in combination with hydrocarbons and other propellants. Generally, it cannot be used alone as a propellant owing to its high vapor pressure. Dimethyl ether is a good solvent and has the unique property of high water solubility, compared to other propellants. It has frequently been used with aqueous aerosols. A coarse, wet, spray is formed when dimethyl ether is used as a propellant.
Dimethyl ether is also used as a propellant in cosmetics such as hair sprays,and in other aerosol products such as air fresheners and fly sprays.
Dimethyl ether is additionally used as a refrigerant.

Safety

Dimethyl ether may be used as a propellant and solvent in topical pharmaceutical aerosols, and is generally regarded as an essentially nontoxic and nonirritant material when used in such applications. However,inhalation of high concentrations of dimethyl ether vapor is harmful. Additionally, skin contact with dimethyl ether liquid may result in freezing of the skin and severe frostbite.
When used in topical formulations, dimethyl ether may exert a chilling effect on the skin, although if it is used as directed the propellant quickly vaporizes and is nonirritating.
LD50 (mouse, inhalation): 386000ppm/30min
LD50 (rat, inhalation): 308g/m3

Carcinogenicity

A lifetime study in rats did not produce cancer or clear, statistically significant evidence of chronic toxicity at 25,000 ppm of dimethyl ether.

Environmental Fate

DME released to the atmosphere would be expected to exist almost entirely in the vapor phase since the vapor pressure is 4450 mmHg at 25 ℃. It is susceptible to photooxidation via vapor phase reaction with photochemically produced hydroxyl radicals. An atmospheric half-life of 5.4 days has been calculated. It will also exhibit very highmobility in soil and, therefore, itmay leach to groundwater. If DME is released to water, it will not be expected either to significantly absorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms, or directly photolyze. No data concerning the biodegradation of DME in environmental media were located but many ethers are known to be resistant to biodegradation. DME would not be expected to bioconcentrate in aquatic organisms.

storage

The liquefied gas is stable when used as a propellant. However, exposure to the air for long periods of time may result in explosive peroxides being slowly formed.
Solutions of liquid dimethyl ether should not be concentrated either by distillation or by evaporation. Dimethyl ether should be stored in tightly closed metal cylinders in a cool, dry place.

Purification Methods

Dry methyl ether by passing over alumina and then BaO, or over CaH2, followed by fractional distillation at low temperatures. Its solubility is 37mL per mL of H2O at 18o, and it is very soluble

Toxicity evaluation

Higher concentrations of DME act on the central nervous system (CNS) to produce narcosis. The effects are rapidly reversible which is consistent with the very rapid bioelimination of the molecule. DME has, in the past, been considered for use as a human anesthetic. It should be noted that this chemical can produce cardiac sensitization similar to the effects of epinephrine.

Incompatibilities

Dimethyl ether is an aggressive solvent and may affect the gasket materials used in aerosol packaging. Oxidizing agents, acetic acid, organic acids, and anhydrides should not be used with dimethyl ether.

Regulatory Status

Included in the FDA Inactive Ingredients Database (topical aerosols). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

More
Less

Dimethyl ether Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202- ; ;
Email
jerry.ma@hanhonggroup.com;jerry.ma@hanhonggroup.com;jerry.ma@hanhonggroup.com
Country
China
ProdList
43255
Advantage
64
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9844
Advantage
79
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725;010-86181995
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12341
Advantage
58
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-3668-0489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28438
Advantage
80
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196;028-84555506- ;028-84555506-
Fax
QQ:800101999
Email
cdhxsj@163.com;cdhxsj@163.com;cdhxsj@163.com
Country
China
ProdList
13362
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432-
Fax
0571-87396431
Email
sales@jhechem.com;
Country
China
ProdList
13965
Advantage
53
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241- ;027-59599240-
Fax
027-59599241
Email
1400878000@qq.com;1400868000@qq.com
Country
China
ProdList
9841
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Please Email
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9550
Advantage
50
Sigma-Aldrich
Tel
021-61415566- ;
Email
orderCN@merckgroup.com;orderCN@merckgroup.com
Country
China
ProdList
48786
Advantage
80
More
Less

View Lastest Price from Dimethyl ether manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Methyl Ether 115-10-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2019-12-31

115-10-6, Dimethyl etherRelated Search:


  • (CH3)2O
  • Methoxymethane
  • Dimethyl ether,Methyl ether
  • Dimethyl Ether Dimethyl Oxide Methyl Oxide
  • Methane, 1,1'-oxybis-
  • DiMethyl ether >=99%
  • Dimethyl ether >=99.9%
  • FK-506 3&#39
  • Simvastatin 4&#39
  • demeond
  • Dymel A
  • dymela
  • Ether, dimethyl
  • Ether, methyl
  • ether,dimethyl
  • ether,dimethyl-
  • ether,methyl
  • Methane, oxybis-
  • Methane,oxybis-
  • oxybis(methane)
  • oxybis-methan
  • Oxybismethane
  • oxybis-Methane
  • RE170
  • RE-170
  • Wood ether
  • woodether
  • METHYL OXIDE
  • METHYL ETHER
  • Dimethyl-13C2 Ether (gas)
  • Methyl Ether (in cylinder without valve)
  • METHYL ETHER, 99+%
  • DIMETHYL ETHER PRESSURE TIN WITH 250 ML (NET ~150 G)
  • DIMETHYL ETHER, CYLINDER WITH 14 L (NET ~8 KG)
  • DIMETHYL ETHER, CYLINDER WITH 7 L (NET ~ 4 KG)
  • DIMETHYL ETHER, CYLINDER WITH 2 L (NET ~ 1.2 KG)
  • DimethylEther(incylinderwithoutvalve)
  • DIMETHYL ETHER
  • DIMETHYL OXIDE
  • METHYLATEDETHER
  • verutraldehyde
  • Dimethyl ether, 2,6-Dimethylhaptan-4-one
  • Methyl Ether (in cylinder without valve) [To use this product charged in cylinder, a valve is required which is sold separately (Product Code:V0030)]
  • Dimethyloxidane
  • Dimethyl ether 99%
  • Dimethyl ether [CAS:115-10-6] 2000mg/l in Methanol
  • Dimethyl ether ISO 9001:2015 REACH
  • 115-10-6
  • CH3OCH3
  • 115106
  • Compressed and Liquefied Gases
  • Synthetic Reagents
  • Gas Cylinders
  • Ethers (Low Boiling point)
  • Organics
  • Ethers (Low Boiling point)
  • Gas Cylinders
  • Synthetic Organic Chemistry