Artemether

Product Name: Artemether
CAS No.: 71963-77-4
Chemical Name: Artemether
Synonyms: artMether;Artimether;ARTHEMETER;ArteMether (SM-224);SM-224;Gvither;ArteMos;ArtenaM;cgp56696;Artesian
CBNumber: CB4248286
Molecular Formula: C16H26O5
Formula Weight: 298.37
MOL File: 71963-77-4.mol

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Artemether Property

Melting point:: 86-88°C
Boiling point:: 359.79°C (rough estimate)
alpha: D19.5 +171° (c = 2.59 in CHCl3)
Density: 1.0733 (rough estimate)
refractive index: 1.6200 (estimate)
storage temp.: room temp
solubility: DMSO: ≥20mg/mL
form: powder
color: off-white to light brown
optical activity: [α]/D +155 to +175°, c = 0.5 in methanol
Merck: 14,815
InChI: InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1
InChIKey: SXYIRMFQILZOAM-HVNFFKDJSA-N
SMILES: O1[C@]23[C@@]4([H])O[C@@](C)(CC[C@@]2([H])[C@H](C)CC[C@@]3([H])[C@@H](C)[C@@H](OC)O4)O1

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 24/25
WGK Germany: 3
RTECS: KD4165000
HS Code: 29329930
Hazardous Substances Data: 71963-77-4(Hazardous Substances Data)
Toxicity: LD50 i.m. in mice: 263 mg/kg (China Cooperative Research Group on Qinghaosu)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H242Heating may cause a fire

H302Harmful if swallowed

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P235Keep cool.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P370+P378In case of fire: Use … for extinction.

P410Protect from sunlight.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A9361
Product name: Artemether
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $90.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR3423
Product name: Artemether
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 200MG
Price: $222
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1042780
Product name: Artemether
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 100mg
Price: $261.6
Updated: 2024/03/01

TCI Chemical

Product number: A2190
Product name: Artemether
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $80
Updated: 2024/03/01

TCI Chemical

Product number: A2190
Product name: Artemether
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $237
Updated: 2024/03/01

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Artemether Chemical Properties,Usage,Production

Description

Artemether is an antiparasitic compound and a derivative of artemisinin . It induces mortality in adult wild-type and pfatp6-mutant P. falciparum but the efficacy is decreased in the mutants (IC₅₀s = 8.2 and 13.5 nM, respectively). Artemether reduces parasitemia in P. falciparum-infected monkeys and P. berghei-infected mice with 50% curative dose (CD₅₀) values of 7.1 and 55 mg/kg, respectively. It also reduces the worm burden of S. mansoni trematodes in mice when used at doses ranging from 200 to 500 mg/kg. Formulations containing artemether have been used in the treatment of malaria.

Chemical Properties

White Solid

Uses

Derivative of Artemisinin (A777500). Antimalarial, used to treat strains of malaria which are multi-drug resistant.

Uses

atypical antidepressant, norepinephrine and dopamine reuptake inhibitor, and nicotinic antagonist

Uses

Artemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when

Definition

ChEBI: An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falcip rum malaria.

General Description

Artemisinin (ART) is a natural compound present in Artemisia annua, a traditional Chinese plant.

Biochem/physiol Actions

Artemether is a methyl ether derivative of artemisinin. It is used against multi-drug resistant strains of the malaria parasite, Plasmodium falciparum, and shows potential in treatment of schistosomiasis.

Safety Profile

Poison by intramuscular route.Experimental reproductive effects. When heated todecomposition it emits acrid smoke and irritating fumes.

target

Antifection

storage

Store at -20°C

Artemether Preparation Products And Raw materials

Raw materials

Preparation Products

Artemisinin

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Artemether Suppliers

Americas 1 Austria 1 Belgium 2 Canada 4 China 392 Colombia 1 Czech Republic 1 Europe 3 France 5 Germany 3 India 132 Italy 1 Japan 1 Philippines 1 South Korea 1 Switzerland 1 United Arab Emirates 1 United Kingdom 17 United States 50 Global 618

GUANGZHOU CHANGTHINKING IMP.&EXP.CO.,LTD

Tel: 020-37651955 13682223272
Fax: 020-87659730
Email: 173901442@qq.com
Country: China
ProdList: 694
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 8908
Advantage: 60

Nanjing bingcheng Biotechnology Co., Ltd.

Tel: 18805194892; 18805194892
Email: 2727751293@qq.com
Country: China
ProdList: 157
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
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View Lastest Price from Artemether manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Artemether 71963-77-4
Price: US $1000.00-400.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-12

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Artemether 71963-77-4
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-08-27

Hebei Dangtong Import and export Co LTD

Product: Artemether 71963-77-4
Price: US $1308.00-1260.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-04-12

71963-77-4, ArtemetherRelated Search:

4-Methoxybenzylchloride p-Anisidine Anisole 3-Methoxybenzaldehyde 4-Methoxyphenylacetone p-Anisaldehyde 2-Methoxyethanol (Trifluoromethoxy)benzene 4-Methoxyphenylacetic acid Quercetin tert-Butyl hydroperoxide tert-Amyl hydroperoxide Arteether ARTEMETHER alpha-Artemether artemisitene ArteMether Tetrahydrofuran Acetate artesunate

methyl-dihydroartemisinine

[3r-(3r,5as,6s,8as,9r,10r,12s,12ar**)]-decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin

ARTEMETHER

ARTHEMETER

Artimether

ArtemetherC16H26O5

cgp56696

dihydroartemisininmethylether

dihydroquinghaosumethylether

Artesaph

Artesian

Decahydro-10-Methoxy-3,6,9-triMethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin

Falcidol

Gvither

Larither

MalarteM

ArteMether (SM-224)

ARTEMTHER

artMether

Artemether [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin

Artemether 71963-77-4

ARTEMETHER PH. INT

3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR)-, (+)

(3R,5aα,8aα,12aR)-Decahydro-10β-methoxy-3,6α,9β-trimethyl-3,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin

(3R,5aα,8aα,12aR)-Decahydro-10β-methoxy-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin

Dihydroartemisin methyl ether

SM-224

WR-254986

(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin

dihydroqinghaosu methyl ether

Artemether (100 mg)

ArteMos

ArtenaM

3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin,decahydro-10-methoxy-3,6,9-trim

5a-beta,6-beta,8a-beta,9-alpha,12-beta,12ar)-(3-alph(+)-ethyl

artemisininelactolmethylether

Artemether&gt

3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-

(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Methoxy-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene

Artemether CP2015

α-(N-Methyl-Benzylamino）-3-Hydroxyacetophenone Hydrochloride

(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene

Artemether USP/EP/BP

Artemetherr

ArtemetherQ: What is Artemether Q: What is the CAS Number of Artemether Q: What is the storage condition of Artemether Q: What are the applications of Artemether

Artemether (1042780)

Artemether, ≥ 98.0%

(+)-Artemether

71963-77-4

963-77-4

C16H26O5

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Antimalarial

chemical reagent

pharmaceutical intermediate