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4-Iodoanisole

Description References
Product Name
4-Iodoanisole
CAS No.
696-62-8
Chemical Name
4-Iodoanisole
Synonyms
1-IODO-4-METHOXYBENZENE;P-IODOANISOLE;4-IODOANISOL;Isoform;p-iodoanisol;4-IODANISOLE;4-lodoanisole;4-METHOXYIODOBENZENE;CREM-α;4-iodoether
CBNumber
CB6450614
Molecular Formula
C7H7IO
Formula Weight
234.03
MOL File
696-62-8.mol
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4-Iodoanisole Property

Melting point:
50-53 °C(lit.)
Boiling point:
237 °C726 mm Hg(lit.)
Density 
1.7904 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in ethanol, ether, chloroform.
form 
Crystalline Powder and Chunks
color 
Off-white to brown
Sensitive 
Light Sensitive
BRN 
1906692
InChIKey
SYSZENVIJHPFNL-UHFFFAOYSA-N
CAS DataBase Reference
696-62-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-iodo-4-methoxy-(696-62-8)
EPA Substance Registry System
Benzene, 1-iodo-4-methoxy- (696-62-8)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
8
TSCA 
Yes
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I7608
Product name
4-Iodoanisole
Purity
98%
Packaging
25g
Price
$46.8
Updated
2024/03/01
Sigma-Aldrich
Product number
I7608
Product name
4-Iodoanisole
Purity
98%
Packaging
100g
Price
$140
Updated
2024/03/01
TCI Chemical
Product number
I0378
Product name
4-Iodoanisole
Purity
>99.0%(GC)
Packaging
25g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
I0378
Product name
4-Iodoanisole
Purity
>99.0%(GC)
Packaging
100g
Price
$82
Updated
2024/03/01
Alfa Aesar
Product number
A12144
Product name
4-Iodoanisole, 98+%
Packaging
25g
Price
$34.1
Updated
2024/03/01
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4-Iodoanisole Chemical Properties,Usage,Production

Description

4-Iodoanisole (chemical formula: C7H7IO) is an organic compound being soluble in ethanol, ether and chloroform. It has a wide range of medicals industrial applications. For example, it can be used as human and animal nutrition products, antiseptics, disinfectants, pharmaceutical intermediates, polarizing films for liquid crystal display (LCD) chemicals. Its iodine derivatives can also be used as organic building blocks and analytic reagents.

References

https://www.fishersci.pt/shop/products/4-iodoanisole-98-7/11480113

Chemical Properties

off-white to brown crystalline powder and chunks. Melting point 51-52 ℃, boiling point 237 ℃ (96.8kPa). Soluble in organic solvents such as alcohol and ether, but insoluble in water. Iodine can be easily separated and analyzed by light.

Uses

4-Iodoanisole is used in wide range of medicals industrial applications as well as in human and animal nutrition products, pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals. Iodine derivatives are also used as organic building blocks, analytical reagents.

Preparation

4-Iodoanisole is synthesized by the reaction of anisole with iodine chloride. Add anisole to glacial acetic acid, stir and slowly add iodine chloride. After the addition was completed, the temperature was refluxed for 3.5h. Cool, pour into ice water, and precipitate p-iodoanisole. After it was separated, the free iodine was washed with 5% sodium sulfite, then washed with water, distilled under reduced pressure, and the fractions with a boiling point of 140-160 °C (5.33 kPa) were collected and cooled to 0 °C for filtration. Wash with methanol and recrystallize to obtain the finished product.

Definition

ChEBI: (alpha-D-mannosyl)7-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine, isoform B (protein) is a member of methoxybenzenes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 2058, 1993 DOI: 10.1021/jo00060a020
Tetrahedron Letters, 27, p. 3497, 1986 DOI: 10.1016/S0040-4039(00)84832-7

Purification Methods

Crystallise 4-iodoanisole from aqueous EtOH and/or distil it under vacuum. [Beilstein 6 H 208, 6 I 109, 6 II 199, 6 III 744, 6 IV 1075.]

4-Iodoanisole Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Iodoanisole Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Sichuan Ruibo Technology Co., Ltd
Tel
+86-817-5586080
Fax
+86-817-5527378
Country
China
ProdList
42
Advantage
69
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 4-Iodoanisole manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Iodoanisole 696-62-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01
R&D Scientific Inc.
Product
4-Iodoanisole 696-62-8
Price
US $397.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-05-12
Henan Fengda Chemical Co., Ltd
Product
4-Iodoanisole 696-62-8
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24

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