3'-Amino-4'-methoxyacetanilide
- Product Name
- 3'-Amino-4'-methoxyacetanilide
- CAS No.
- 6375-47-9
- Chemical Name
- 3'-Amino-4'-methoxyacetanilide
- Synonyms
- TIMTEC-BB SBB000217;o-Amino-p-acetanisidine;5-ACETAMIDO-O-ANISIDINE;3-Amino-p-acetanisidide;4-ACETAMIDO-2-AMINOANISOLE;4-ACETAMINO-2-AMINOANISOLE;2-AMINO-4-ACETAMIDOANISOLE;p-Acetanisidide, 3'-amino-;2-Amino-4-acetaminoanisole;3-AMINO-4-METHOXYACETANILINE
- CBNumber
- CB1104453
- Molecular Formula
- C9H12N2O2
- Formula Weight
- 180.2
- MOL File
- 6375-47-9.mol
3'-Amino-4'-methoxyacetanilide Property
- Melting point:
- 109°C
- Boiling point:
- 313.03°C (rough estimate)
- Density
- 1.1819 (rough estimate)
- refractive index
- 1.5373 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 14.23±0.70(Predicted)
- color
- White to Gray to Brown
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C9H12N2O2/c1-6(12)11-7-3-4-9(13-2)8(10)5-7/h3-5H,10H2,1-2H3,(H,11,12)
- InChIKey
- SJWQCBCAGCEWCV-UHFFFAOYSA-N
- SMILES
- C(NC1=CC=C(OC)C(N)=C1)(=O)C
- CAS DataBase Reference
- 6375-47-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Amino-4-acetamino anisole(6375-47-9)
- EPA Substance Registry System
- Acetamide, N-(3-amino-4-methoxyphenyl)- (6375-47-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A1064
- Product name
- 3'-Amino-4'-methoxyacetanilide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $33
- Updated
- 2024/03/01
- Product number
- A610785
- Product name
- 3''-Amino-4''-methoxyacetanilide
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A610785
- Product name
- 3''-Amino-4''-methoxyacetanilide
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA120140
- Product name
- N-(3-Amino-4-methoxyphenyl)acetamide
- Packaging
- 250mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 4648-1-95
- Product name
- 3'-Amino-4'-methoxyacetanilide
- Packaging
- 5G
- Price
- $128
- Updated
- 2021/12/16
3'-Amino-4'-methoxyacetanilide Chemical Properties,Usage,Production
Chemical Properties
White crystals. Melting point 116-118 ℃.
Uses
3'-Amino-4'-methoxyacetanilide mainly used as a disperse dye intermediate
Synthesis
615-05-4
108-24-7
6375-47-9
In conjunction with the accompanying drawings, a continuous flow reactor equipped with a solid-liquid separator was connected to a constant-flow pressure pump and a nitrogen cylinder, respectively. First, nitrogen was introduced to displace the air in the reaction system, followed by heating the first part of the reactor to the set temperature using an oil bath and adjusting the pressure of the first reactor to the desired value by means of a back pressure valve. A methanol solution of 2,4-dinitroanisole with catalyst (1% Pd/C, particle size <100 μm) was introduced from inlet 1 via a metering pump, preheated and fed into the tubular continuous flow reactor. At the same time, hydrogen was introduced from inlet 2 via a gas flow meter into the same reactor. After reacting at a specific temperature and pressure for a certain period of time, the mixture enters a gas-liquid-solid separator, where the catalyst is separated and recycled, while the liquid phase is introduced directly into the second reactor through inlet 3. In the second reactor, acid and acetic anhydride are added from feed ports 4 and 5, respectively, via a metering pump, and mixed with hydrogen and reacted at a set temperature. Upon completion of the reaction, the mixture entered the post-treatment tank, and was subjected to filtration, distillation to recover methanol, washing and recrystallization steps to finally obtain 3-amino-4-methoxyacetanilide. The process has a maximum yield of 99% and a product purity of 99.9% (see Example 11).
References
[1] Patent: CN106966915, 2017, A. Location in patent: Paragraph 0031; 0032; 0033; 0034; 0035; 0036-0042
[2] Patent: CN105348132, 2016, A. Location in patent: Paragraph 0066; 0067
[3] Patent: CN104926679, 2016, B. Location in patent: Paragraph 0016; 0017; 0019; 0021
[4] Patent: CN108409593, 2018, A. Location in patent: Paragraph 0037; 0047-0049
[5] Patent: CN108440333, 2018, A. Location in patent: Paragraph 0037; 0056-0064
3'-Amino-4'-methoxyacetanilide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3'-Amino-4'-methoxyacetanilide manufacturers
- Product
- 3′-Amino-4′-methoxyacetanilide 6375-47-9
- Price
- US $45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-31
- Product
- 3'-Amino-4'-methoxyacetanilide 6375-47-9
- Price
- US $60.00/KG
- Min. Order
- 1KG
- Purity
- 99.9%
- Supply Ability
- 100000kg
- Release date
- 2024-09-24
- Product
- 3"-Amino-4"-methoxyacetanilide 6375-47-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11