(+)-Taddol

Product Name: (+)-Taddol
CAS No.: 93379-49-8
Chemical Name: (+)-Taddol
Synonyms: ((4S,5S);97.0%(LC);(+)-TADDOL;(S,S)-taddol;SEEBACH REAGENT;bis(diphenylmethanol);(4S,5S)-2,2-Dimethyl-α;(+)-4,5-Bis[hydroxy(diphenyL;meso-2,3-Diphenylsuccinonitrile>(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TE
CBNumber: CB6152969
Molecular Formula: C31H30O4
Formula Weight: 466.57
MOL File: 93379-49-8.mol

More

Less

(+)-Taddol Property

Melting point:: 193-196 °C(lit.)
alpha: -62.6 º (c=1 in chloroform)
Boiling point:: 633.2±50.0 °C(Predicted)
Density: 1.200±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 12.28±0.29(Predicted)
color: White to Almost white
optical activity: [α]19/D +67°, c = 1 in chloroform
BRN: 4724097
InChIKey: RNSJHECWLNVNFE-LOYHVIPDSA-N
CAS DataBase Reference: 93379-49-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29329990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 264997
Product name: (4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol
Purity: 97%
Packaging: 1g
Price: $94.3
Updated: 2022/05/15

TCI Chemical

Product number: B2048
Product name: (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane
Purity: >97.0%(HPLC)
Packaging: 1g
Price: $95
Updated: 2024/03/01

TCI Chemical

Product number: B2048
Product name: (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane
Purity: >97.0%(HPLC)
Packaging: 5g
Price: $262
Updated: 2024/03/01

Strem Chemicals

Product number: 08-1258
Product name: (4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)
Packaging: 1g
Price: $46
Updated: 2024/03/01

TRC

Product number: T779313
Product name: (+)-TADDOL
Packaging: 50mg
Price: $60
Updated: 2021/12/16

More

Less

(+)-Taddol Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Ligand for enantioselective Lewis-acid mediated Diels-Alder, allyltitanation of aldehydes, and Michael-Mukaiyama additions promoted by chiral Ti-complexes.

Preparation

Preparative Methods of (4R,5R)-2,2-Dimethyl-4,5-bis(hydroxydiphenylmethyl)-1,3-dioxolane: chiral titanates are usually prepared by mixing dichlorodiisopropoxytitanium and a chiral 1,4-diol in toluene. Other solvents such as ether and dichloromethane can also be employed. The alcohol exchange reaction takes place immediately at rt. Wherever necessary, liberated isopropyl alcohol is removed by azeotropic removal with toluene. The chiral 1,4-diols are prepared from dimethyl (or diethyl) tartrate by a two-step procedure comprising acetalization followed by the addition of an aryl Grignard reagent.

storage

Chiral titanates are usually prepared just before use under argon atmosphere. Care should be taken to avoid moisture, especially when a catalytic amount of the reagent is used.

(+)-Taddol Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid Bromobenzene Tetrahydrofuran Ethyl acetate Dichloromethane Methanol L(+)-Tartaric acid

Preparation Products

More

Less

(+)-Taddol Suppliers

Americas 1 China 110 Europe 1 France 1 Germany 4 India 3 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 10 United States 21 Global 155

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
Email: zdcomcon@126.com
Country: China
ProdList: 3461
Advantage: 50

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9810
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19183
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6791
Advantage: 65

More

Less

View Lastest Price from (+)-Taddol manufacturers

Career Henan Chemical Co

Product: (+)-Taddol 93379-49-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 100KG
Release date: 2019-08-29

93379-49-8, (+)-TaddolRelated Search:

Dichlorodiphenylsilane Dimethyl phthalate 1,5-Diphenylcarbazide 1,3-Diphenyl-2-thiourea 3,4'-DIAMINODIPHENYLMETHANE Chlorodiphenylphosphine Diphenyldimethoxysilane Dimethyl sulfide Dimethyl fumarate N,N-Dimethylformamide Dimethyl ether Dimethyl sulfoxide 2,2-Dimethyl-1,3-dioxolane-4-methanol ETHANE 1,3-Dioxolane 2,5-Dimethyl-2,5-hexanediol 2,2,4-TRIMETHYL-1,3-DIOXOLANE (R)-(-)-4-PHENYL-2-BUTANOL

(+)-4,5-BIS[HYDROXY(DIPHENYL)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE

(4S,5S)-2,2-DIMETHYL-ALPHA,ALPHA,ALPHA',ALPHA'-TETRAPHENYLDIOXOLANE-4,5-DIMETHANOL

(4S,5S)-4,5-BIS(DIPHENYLHYDROXYMETHYL)-2,2-DIMETHYL-DIOXOLANE

(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TETRAPHENYL-D-THREITOL

(2S,3S)-(+)-1,1,4,4-TETRAPHENYL-2,3-(2-PROPYLIDENEDIOXY)-BUTANE-1,4-DIOL

(2S,3S)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TETRAPHENYL-1,2,3,4-BUTANETETROL

(2S,3S)-(+)-4,5-BIS(DIPHENYLHYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(+)-TADDOL

SEEBACH REAGENT

1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-.alpha.,.alpha.,.alpha.,.alpha.-tetraphenyl-, (4S,5S)-

(4s,5s)-2,2-dimethyl-α,α,α',α'-tetraphenyldioxolane-4,5-dimethanol

(+)-Taddol (2S,3S)-(-)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyl-1,3-dioxolane

(+)-TRANS-4,5-BIS-(DIPHENYL-HYDROXYMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE

(+)-TRANS-ALPHA,ALPHA'-(2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIYL)BIS(DIPHENYLMETHANOL)

(+)-trans-A,A-(2,2-dimethyl-1,3-dioxolane -4,5-D

Bishydroxydiphenylmethyldimethyldioxolane

1,1,4,4-Tetraphenyl-2,3,0-isopropylidene-D-threitol

(4S,5S)-2,2-Dimethyl-alpha,alpha,alpha',alpha'-tetraphenyldioxolane-4,5-dimethan

(2,2-)Dimethy-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane- 4,5-dimethanol

((4S,5S)

-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)

bis(diphenylmethanol)

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane- 4,5-dimethanol,99%e.e.

1,1,4,4-Tetraphenyl-2,3-O-isopropylidene-L-threitol

[(4S,5S)-5-[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-diphenylmethanol

(+)-2,3-O-ISOPROPYLIDENE-1,1,4,4-TE

(4S,5S)-2,2-DIMETHYL-A,A,A'',A'',-TETRAPHENYLDIOXOLANE-4,5-DIMETHANOL

(+)-trans-α,α'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenlmethanol)

(2,2-dimethyl)-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol

(4S,5S)-4,5-Bis(diphenylhydroxymethyl)-2,2-dimethyldioxolane, (+)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-D-threitol, (+)-trans-α,αμ-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)

(4S)-α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4α,5β-dimethanol

(4S,5S)-α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol

2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4α,5β-dimethanol

α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4α,5β-bismethanol

2,2-Dimethyl-1,3-dioxolane-4,5-bis(α,α-diphenylmethanol)

α,α'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(α-phenylbenzyl alcohol)

α,α,α',α'-Tetraphenyl-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol

((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol)

(+)-trans-alpha,alpha'-(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(diphenylmethanol) (2S,3S)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-1,2,3,4-butanetetrol (+)-2,3-O-Isopropylidene-1,1,4,4-tetraphenyl-D-threitol

(+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane,97%

(4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol ,98%

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol

(S,S)-taddol

(4S,5S)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)

97.0%(LC)

(4S,5S)-2,2-Dimethyl-α

'-tetraphenyl-1,3-dioxolane-4,5-dimethanol, 98% (99% ee)

Neu5GcAc[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP&gt

Methyl2,3,4,6-Tetra-O-pivaloyl-D-mannopyranoside&gt

Neu5Acα(2-6)Galβ(1-3)GlcNAc-β-pNP&gt

meso-2,3-Diphenylsuccinonitrile&gt

Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP&gt

(+)-4,5-Bis[hydroxy(diphenyL

1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-α4,α4,α5,α5-tetraphenyl-, (4S,5S)-

(-)-2,3-O-isopropylidene-1,1,4,4-tetra-phenyl-D-threitol

(4S,5S)-2,2-Dimethyl-α,α,α′,α′-tetraphenyldioxolane-4,5-dimethanol

(+)-4,5-BIS[HYDROXY(DIPHENYL)METHYL]-2,2-DIMETHYL-1,3-DIOXOLANE