ChemicalBook > CAS DataBase List > 2,5-Dimethyl-2,5-hexanediol

2,5-Dimethyl-2,5-hexanediol

Product Name
2,5-Dimethyl-2,5-hexanediol
CAS No.
110-03-2
Chemical Name
2,5-Dimethyl-2,5-hexanediol
Synonyms
2,5-DIMETHYLHEXANE-2,5-DIOL;2,5-Hexanediol, 2,5-dimethyl-;1,1,4,4-Tetramethyl-1,4-butanediol;nsc5595;ai3-20685;5-hexanediol;-2,5-hexanedioL;DiMethyl-2,5-hexan;dimethylhexanediol;2,5-Dimethyl-2,5-hex
CBNumber
CB3335426
Molecular Formula
C8H18O2
Formula Weight
146.23
MOL File
110-03-2.mol
More
Less

2,5-Dimethyl-2,5-hexanediol Property

Melting point:
86-90 °C (lit.)
Boiling point:
214-215 °C (lit.)
Density 
0,898 g/cm3
vapor pressure 
0.18Pa at 20℃
refractive index 
1.4429 (estimate)
Flash point:
126 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Flakes
pka
15.07±0.29(Predicted)
color 
White
Odor
mild camphor
Water Solubility 
SOLUBLE
BRN 
1361437
InChIKey
ZWNMRZQYWRLGMM-UHFFFAOYSA-N
LogP
0.21 at 23℃
CAS DataBase Reference
110-03-2(CAS DataBase Reference)
NIST Chemistry Reference
2,5-Hexanediol, 2,5-dimethyl-(110-03-2)
EPA Substance Registry System
2,5-Hexanediol, 2,5-dimethyl- (110-03-2)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29053980
Hazardous Substances Data
110-03-2(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
143618
Product name
2,5-Dimethyl-2,5-hexanediol
Purity
97%
Packaging
100g
Price
$48.7
Updated
2024/03/01
Sigma-Aldrich
Product number
143618
Product name
2,5-Dimethyl-2,5-hexanediol
Purity
97%
Packaging
500g
Price
$101
Updated
2024/03/01
TCI Chemical
Product number
D1167
Product name
2,5-Dimethyl-2,5-hexanediol
Purity
>99.0%(GC)
Packaging
25g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
D1167
Product name
2,5-Dimethyl-2,5-hexanediol
Purity
>99.0%(GC)
Packaging
500g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
A11984
Product name
2,5-Dimethyl-2,5-hexanediol, 97%
Packaging
100g
Price
$22.65
Updated
2024/03/01
More
Less

2,5-Dimethyl-2,5-hexanediol Chemical Properties,Usage,Production

Chemical Properties

white crystalline flakes. Soluble in water 20°C 140g/L.

Uses

2,5-Dimethyl-2,5-hexanediol was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.

Uses

2,5-Dimethyl-2,5-hexanediol is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane to produce polyethylene copolymers and polyethylene rubbers. It is also could be used to prepared nickel-containing Complex Reducing Agents (termed NiCRA)[1].

Preparation

The raw materials 2,5-Dimethyl-3-hexyne-2,5-diol (37.4 g, 263 mmol), ethyl acetate (60 mL), and Pd/C catalyst (0.285 g, 2.63 mmol, 1 mol %) were added to an autoclave. The hydrogen gas was slowly added to 10 bar. When the hydrogenation reaction was performed for 12 hours and then removed the hydrogen gas. Finally, 2,5-Dimethyl-2,5-hexanediol is obtained by purification.

Synthesis Reference(s)

Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377

General Description

2,5-Dimethyl-2,5-hexanediol on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.

Purification Methods

Purify the diol by fractional crystallisation. Then the diol is dissolved in hot acetone, treated with activated charcoal, and filtered while hot. The solution is cooled and the diol is filtered off and washed well with cold acetone. The crystallisation process ia repeated several times, and the crystals are dried under a vacuum in a freeze-drying apparatus [Goates et al. J Chem Soc, Faraday Trans 1 78 3045 1982]. [Beilstein 1 IV 2600.]

References

[1] Feghouli G, et al. Activation of reducing agents. Sodium hydride containing complex reducing agents 29. Epimerization of alcohols by nickel-containing complex reducing agents (NiCRA). Tetrahedron Letters, 1988; 9: 285–290.

2,5-Dimethyl-2,5-hexanediol Preparation Products And Raw materials

Raw materials

2,5-Hexanediol Nickel 3-HEXYNE 3-Methyl butynol

Preparation Products

More
Less

2,5-Dimethyl-2,5-hexanediol Suppliers

Americas 1 Belgium 3 Canada 2 China 286 Europe 5 France 2 Germany 14 India 11 Japan 5 Singapore 1 South Korea 1 Switzerland 2 The Netherlands 3 Ukraine 1 United Kingdom 13 United States 47 USA 1 Global 399
Sichuan Zhongbang Pharma CO.，LTD
Tel
0830-0830-2585019 13679670161
Fax
0830-2589033
Email
sales2@zhongbangst.com
Country
China
ProdList
104
Advantage
69
Changzhou Fourman Chemical Co., Ltd.
Tel
0519-89882557 13912311481
Fax
0519-8988-2559
Email
fourmanchem@163.com
Country
China
ProdList
78
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
More
Less

View Lastest Price from 2,5-Dimethyl-2,5-hexanediol manufacturers

Jinan Finer Chemical Co., Ltd
Product
2,5-Dimethyl-2,5-hexanediol 110-03-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500mt
Release date
2022-06-23
hebei hongtan Biotechnology Co., Ltd
Product
2,5-Dimethyl-2,5-hexanediol 110-03-2
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-03-25
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
2,5-Dimethyl-2,5-hexanediol 110-03-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99.6%
Supply Ability
100000
Release date
2024-04-24

110-03-2, 2,5-Dimethyl-2,5-hexanediolRelated Search:

Dimethyl ether ETHANE Dimethyl fumarate Dacthal Dimethyl sulfate 2,5-Hexanediol Dimethicone POLY(1 6-HEXAMETHYLENE ADIPATE) AVERAG& Dimethyl sulfoxide Dimethyl disulfide N,N-Dimethylformamide N,N-Dimethylacetamide Dimethyl sulfone Poly(dimethylsiloxane) Dimethyl carbonate 2-Methyl-2,4-pentanediol 2,5-Dimethyl-3-hexyne-2,5-diol PHORBOL 12-MYRISTATE 13-ACETATE

  • 1,1,4,4-Tetramethyl-1,4-butanediol
  • 2,5-dimethyl-5-hexanediol
  • 5-Hexanediol,2,5-dimethyl-2
  • DiMethyl-2,5-hexan
  • 2,5-Dimethyl-2,5-hex
  • 2,5-DiMethyl-2,5-hexanediol, 99% 250GR
  • 2,5-Dimethyl-2,5-hexanediol,99%
  • 2,5-DiMethyl-2,5-hexanediol, 99.5%
  • 5-hexanediol
  • 2, 5 - diMethyl - 2, 5 - diol
  • 2,5-Dimethyl-2,5-hexanediol 97%
  • ai3-20685
  • dimethylhexanediol
  • nsc5595
  • 2,5-DIHYDROXY-2,5-DIMETHYLHEXANE
  • 2,5-DIMETHYLHEXANE-2,5-DIOL
  • 2,5-DIMETHYLHEXAN-2,5-DIOL
  • 2,5-DIMETHYL-2,5-HEXANDIOL
  • 2,5-DIMETHYL-2,5-HEXANEDIOL
  • 2,5-Hexanediol, 2,5-dimethyl-
  • 2,5-DIMETHYLHEXANEDIOL
  • 2,5-DIMETHYLOHEXANEDIOL
  • 2，5-dimethyl-2，5-hexadiol
  • 7,12-dimethylbenzo[a]anthracene-5,6-dione
  • 2,5-Dimethyl-2,5-hexanediol &gt
  • 2,5-Dimethyl-2,5-hexanediol Basic information
  • -2,5-hexanedioL
  • 2,5-Dimethyl-2,5-hexanediol, ≥ 99.0%
  • 110-03-2
  • CH3CCH3OHCH2CH2CCH3OHCH3
  • CH32COHCH2CH2COHCH32
  • Building Blocks
  • Organic Building Blocks
  • Polyols
  • Oxygen Compounds
  • Organic Building Blocks
  • Oxygen Compounds
  • Polyols
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Oxygen Compounds
  • bc0001