2,5-Dimethyl-2,5-hexanediol
- Product Name
- 2,5-Dimethyl-2,5-hexanediol
- CAS No.
- 110-03-2
- Chemical Name
- 2,5-Dimethyl-2,5-hexanediol
- Synonyms
- 2,5-DIMETHYLHEXANE-2,5-DIOL;2,5-Hexanediol, 2,5-dimethyl-;1,1,4,4-Tetramethyl-1,4-butanediol;nsc5595;ai3-20685;5-hexanediol;-2,5-hexanedioL;DiMethyl-2,5-hexan;dimethylhexanediol;2,5-Dimethyl-2,5-hex
- CBNumber
- CB3335426
- Molecular Formula
- C8H18O2
- Formula Weight
- 146.23
- MOL File
- 110-03-2.mol
2,5-Dimethyl-2,5-hexanediol Property
- Melting point:
- 86-90 °C (lit.)
- Boiling point:
- 214-215 °C (lit.)
- Density
- 0,898 g/cm3
- vapor pressure
- 0.18Pa at 20℃
- refractive index
- 1.4429 (estimate)
- Flash point:
- 126 °C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Crystalline Flakes
- pka
- 15.07±0.29(Predicted)
- color
- White
- Odor
- mild camphor
- Water Solubility
- SOLUBLE
- BRN
- 1361437
- InChIKey
- ZWNMRZQYWRLGMM-UHFFFAOYSA-N
- LogP
- 0.21 at 23℃
- CAS DataBase Reference
- 110-03-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 2,5-Hexanediol, 2,5-dimethyl-(110-03-2)
- EPA Substance Registry System
- 2,5-Hexanediol, 2,5-dimethyl- (110-03-2)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29053980
- Hazardous Substances Data
- 110-03-2(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 143618
- Product name
- 2,5-Dimethyl-2,5-hexanediol
- Purity
- 97%
- Packaging
- 100g
- Price
- $48.7
- Updated
- 2024/03/01
- Product number
- 143618
- Product name
- 2,5-Dimethyl-2,5-hexanediol
- Purity
- 97%
- Packaging
- 500g
- Price
- $101
- Updated
- 2024/03/01
- Product number
- D1167
- Product name
- 2,5-Dimethyl-2,5-hexanediol
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $20
- Updated
- 2024/03/01
- Product number
- D1167
- Product name
- 2,5-Dimethyl-2,5-hexanediol
- Purity
- >99.0%(GC)
- Packaging
- 500g
- Price
- $77
- Updated
- 2024/03/01
- Product number
- A11984
- Product name
- 2,5-Dimethyl-2,5-hexanediol, 97%
- Packaging
- 100g
- Price
- $22.65
- Updated
- 2024/03/01
2,5-Dimethyl-2,5-hexanediol Chemical Properties,Usage,Production
Chemical Properties
white crystalline flakes. Soluble in water 20°C 140g/L.
Uses
2,5-Dimethyl-2,5-hexanediol was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.
Uses
2,5-Dimethyl-2,5-hexanediol is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane to produce polyethylene copolymers and polyethylene rubbers. It is also could be used to prepared nickel-containing Complex Reducing Agents (termed NiCRA)[1].
Preparation
The raw materials 2,5-Dimethyl-3-hexyne-2,5-diol (37.4 g, 263 mmol), ethyl acetate (60 mL), and Pd/C catalyst (0.285 g, 2.63 mmol, 1 mol %) were added to an autoclave. The hydrogen gas was slowly added to 10 bar. When the hydrogenation reaction was performed for 12 hours and then removed the hydrogen gas. Finally, 2,5-Dimethyl-2,5-hexanediol is obtained by purification.
Synthesis Reference(s)
Synthesis, p. 165, 1981 DOI: 10.1055/s-1981-29377
General Description
2,5-Dimethyl-2,5-hexanediol on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines.
Purification Methods
Purify the diol by fractional crystallisation. Then the diol is dissolved in hot acetone, treated with activated charcoal, and filtered while hot. The solution is cooled and the diol is filtered off and washed well with cold acetone. The crystallisation process ia repeated several times, and the crystals are dried under a vacuum in a freeze-drying apparatus [Goates et al. J Chem Soc, Faraday Trans 1 78 3045 1982]. [Beilstein 1 IV 2600.]
References
[1] Feghouli G, et al. Activation of reducing agents. Sodium hydride containing complex reducing agents 29. Epimerization of alcohols by nickel-containing complex reducing agents (NiCRA). Tetrahedron Letters, 1988; 9: 285–290.
2,5-Dimethyl-2,5-hexanediol Preparation Products And Raw materials
Raw materials
Preparation Products
2,5-Dimethyl-2,5-hexanediol Suppliers
View Lastest Price from 2,5-Dimethyl-2,5-hexanediol manufacturers
- Product
- 2,5-Dimethyl-2,5-hexanediol 110-03-2
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-03-25
- Product
- 2,5-Dimethyl-2,5-hexanediol 110-03-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500mt
- Release date
- 2022-06-23
- Product
- 2,5-Dimethyl-2,5-hexanediol 110-03-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99.6%
- Supply Ability
- 100000
- Release date
- 2024-04-24