1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol

Product Name: 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
CAS No.: 1707-77-3
Chemical Name: 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
Synonyms: (1S,2S)-1,2-bis((R)-2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol;D-MANNITOL DIACETONIDE;1,2:5,6-DI-O-ISOPROPYLIDENE-D-MANNITOL;1,2-bis(2,2-dimethyl-1,3-dioxolan-4-yl)-1,2-ethanediol;NSC 47987;NSC 67545;NSC 89874;DIACETONE-D-MAN;idene-D-mannitoL;D-Mannitol diaceton
CBNumber: CB2741824
Molecular Formula: C12H22O6
Formula Weight: 262.3
MOL File: 1707-77-3.mol

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1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Property

Melting point:: 120-122 °C(lit.)
alpha: 6 º (c=5, Chloroform)
Boiling point:: 382.0±32.0 °C(Predicted)
Density: 1.175±0.06 g/cm3(Predicted)
refractive index: 6.5 ° (C=8, CHCl3)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: methanol: 100 mg/mL, clear, colorless
form: Crystalline Powder
pka: 12.98±0.20(Predicted)
color: White
optical activity: [α]/D +6.0±1.0°, c = 5 in chloroform
BRN: 83765
InChIKey: ODYBCPSCYHAGHA-ZYUZMQFOSA-N
CAS DataBase Reference: 1707-77-3(CAS DataBase Reference)
NIST Chemistry Reference: D-Mannitol, 1,2:5,6-bis-o-(1-methylethylidene)-(1707-77-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36/37-26
WGK Germany: 3
F: 10-21
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 296406
Product name: 1,2:5,6-Di-O-isopropylidene-D-mannitol
Purity: 98%
Packaging: 5g
Price: $72.4
Updated: 2023/06/20

Sigma-Aldrich

Product number: 296406
Product name: 1,2:5,6-Di-O-isopropylidene-D-mannitol
Purity: 98%
Packaging: 25g
Price: $182
Updated: 2023/06/20

TCI Chemical

Product number: D2024
Product name: 1,2:5,6-Di-O-isopropylidene-D-mannitol
Purity: >97.0%(GC)
Packaging: 5g
Price: $24
Updated: 2024/03/01

TCI Chemical

Product number: D2024
Product name: 1,2:5,6-Di-O-isopropylidene-D-mannitol
Purity: >97.0%(GC)
Packaging: 25g
Price: $65
Updated: 2024/03/01

Alfa Aesar

Product number: L12127
Product name: 1,2:5,6-Di-O-isopropylidene-D-mannitol
Packaging: 5g
Price: $41.65
Updated: 2024/03/01

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1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Nebivolol intermediate.

Purification Methods

Although quite soluble in H2O, it gives a purer product when crystallised from this solvent, forming needles [Baer J Am Chem Soc 67 338 1945, NMR: Curtis et al. J Chem Soc, Perkin Trans 1 1756 1977]. [Beilstein 19/11 V 589.]

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol

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1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol Suppliers

Americas 1 Belgium 4 Canada 4 China 265 Europe 4 France 1 Germany 8 India 28 Japan 2 Slovakia 1 South Korea 1 Switzerland 6 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 45 Global 392

AILY INTL CHEMICAL CORP LTD

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View Lastest Price from 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol 1707-77-3
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-11

Shanghai Joiny Pharmaceutical Co.,LTD

Product: 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol 1707-77-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2024-12-04

Hebei Weibang Biotechnology Co., Ltd

Product: 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol 1707-77-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-01

1707-77-3, 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitolRelated Search:

Dimethyl sulfate Dimethyl sulfoxide N,N-Dimethylformamide Dacthal Hydroxyacetone Mannitol Dimethyl sulfide Dimethyl ether D-Mannitol Dimethyl fumarate Dimethyl carbonate Diacetone acrylamide Diacetone Alcohol ETHANE Diacetone-D-glucose 4-METHYL-1,3-DIOXOLANE 1,2,6-Hexanetriol 3-Methoxy-1-butanol

DIACETONE-D-MAN

DIACETONE-D-MANNITOL

D-MANNITOL DIACETONIDE

1,2:5,6-ISOPROPYLIDENE-D-MANNITOL

1,2,5,6-DI-O-ISOPROPYLIDENE-D-MANNITOL

1,2:5,6-DI-O-ISOPROPYLIDENE-D-MANNITOL

1,2:5,6-bis-o-(1-methylethylidene)-d-mannitol

1,2:5,6-BIS-O-(1-METHYLETHYLIDENE)-D-MARNITOL

1,2-bis(2,2-dimethyl-1,3-dioxolan-4-yl)-1,2-ethanediol

1,2:5,6-Bis-O-(1-met

1,2,5,6-Di-O-isopropylidene-D-mannitol ,98%

1,2:5,6-Di-O-isopropylidene-D-maitol

1,2,5,6-Diacetone-D-Mannitol (Mannitol diacetonide)

D-(+)-1,2:5,6-Di-O-isopropylideneMannitol

D-Mannitol 1,2:5,6-Bis-acetonide

NSC 47987

NSC 67545

NSC 89874

(1R,2R)-1,2-bis[(4S)-2,2-diMethyl-1,3-dioxolan-4-yl]ethane-1,2-diol

D-Mannitol diaceton

1,2:5,6-Di-O-isopropylidene-D-Mannitol, 96%, 96%

1,2:5,6-Bis-O-(1-methylethylide

(1S,2S)-1,2-bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol

5,6-Bis-O-(1-methylethylidene)-D-mannitol

1,2,5,6-DI-O-ISOPROPYLLIDINE-D-MANITOL

Diacetone-D-mannitol, ≥98%,GC

N'-(6-chloro-2-methoxy-9-acridinyl)ethane-1,2-diamine

1,2:5,6-Bis-o-(1-methylidene)-D-mannitol

(1S,2S)-1,2-bis((R)-2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol

1,2,5,6-Diisopropylidene-D-mannitol

1,2-5,6-Diacetone D-mannitol

Diisopropylidene mannitol

Mannitol, 1,2:5,6-di-O-isopropylidene-, D

1,2,5,6-DI-Isopopylidene-D-Mannitol

Isopropylidene-D-Mannitol

(2,2,2',2'-TETRAMETHYL-[4,4']BI[[1,3]DIOXOLANYL]-5-YL)-METHANOL

1 2:5 6-DI-O-ISOPROPYLIDENE-D-MANNITOL 98%

1,2:5,6-DI-O-ISOPROPYLIDINE-D-MANNITOL

D-Mannitol, 1,2:5,6-bis-O-(1-methylethylidene)-

(1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolane-4-yl]-1,2-ethanediol

(1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolane-4-yl]ethylene glycol

(1S,2S)-1,2-Bis[(4R)-2,2-dimethyl-1,3-dioxolane-4β-yl]ethylene glycol

1-O,2-O:5-O,6-O-Bis(1-methylethylidene)-D-mannitol

Mannitol diacetonide

1,2:5,6-Di-O-isopropylidene-D-mannitol&gt

1,2:5,6-Di-O-isopropyL

idene-D-mannitoL

1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol USP/EP/BP

(+)-1,2:5,6-di-O-isopropylidene-D-mannitol

1,2:5,6- Di-o- Isopropyide- D- Manitol

1707-77-3

C12H22O6

Specialty Synthesis

Monosaccharides

O-Substituted Sugars

Sugar Alcohols

Dioxanes & Dioxolanes

Sugars