ChemicalBook > CAS DataBase List > 2-(2-Bromoethyl)-1,3-dioxolane

2-(2-Bromoethyl)-1,3-dioxolane

Product Name
2-(2-Bromoethyl)-1,3-dioxolane
CAS No.
18742-02-4
Chemical Name
2-(2-Bromoethyl)-1,3-dioxolane
Synonyms
Bromoethyldioxolane;2KG;)-1,3-dioxoL;2-(2-BromoethyL;2-(2-Bromoethyl)-1,3;2-bromo-2-(2-ethyl)dioxolane;2-(2-Bromoethyl)-1,3-dioxola;2-(2-BROMOETHYL)-1,3-DIOXOLANE;3-Bromopropanal ethylene acetal;1,3-Dioxolane, 2-(2-bromoethyl)-
CBNumber
CB1156942
Molecular Formula
C5H9BrO2
Formula Weight
181.03
MOL File
18742-02-4.mol
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2-(2-Bromoethyl)-1,3-dioxolane Property

Boiling point:
68-70 °C8 mm Hg(lit.)
Density 
1.542 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.479(lit.)
Flash point:
149 °F
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly)
form 
clear liquid
Specific Gravity
1.541.542
color 
brownish-yellow
Water Solubility 
immiscible
Sensitive 
Light Sensitive
BRN 
103516
InChIKey
GGZQLTVZPOGLCC-UHFFFAOYSA-N
CAS DataBase Reference
18742-02-4(CAS DataBase Reference)
NIST Chemistry Reference
2-(2-Bromoethyl)-1,3-dioxolane(18742-02-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
2
8-9
HazardClass 
6.1
PackingGroup 
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
230995
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
96%
Packaging
10g
Price
$72.1
Updated
2024/03/01
Sigma-Aldrich
Product number
230995
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
96%
Packaging
50g
Price
$256
Updated
2024/03/01
TCI Chemical
Product number
B1132
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
>90.0%(GC)
Packaging
25g
Price
$97
Updated
2024/03/01
TCI Chemical
Product number
B1132
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
>90.0%(GC)
Packaging
100g
Price
$297
Updated
2024/03/01
Alfa Aesar
Product number
A11441
Product name
2-(2-Bromoethyl)-1,3-dioxolane, 95%, stab. with silver
Packaging
10g
Price
$44.65
Updated
2024/03/01
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2-(2-Bromoethyl)-1,3-dioxolane Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow or brown liquid

Uses

Alkylating agent for amines,1 dithianes,2 and carboximides,3 and via the Grignard reagent, aldehydes.4

Uses

2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures. It is also used as flavouring agent.

General Description

Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride affords the key organotrifluoroborate reagent.

Purification Methods

Dissolve it in pentane, wash with 5% aqueous NaHCO3, dry (Na2SO4), and evaporate. Distil the residue. [NMR: Büchi & Wüest J Org Chem 34 1122 1969, Kriesat & Gisvold J Pharm Sci 60 1250 1971, Beilstein 19/1 V 69.]

2-(2-Bromoethyl)-1,3-dioxolane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-Bromoethyl)-1,3-dioxolane Suppliers

Zhengzhou KeYulong chemical products Co., Ltd
Tel
17319789407
Fax
0371-53335504
Email
Keyulongchem@163.com
Country
China
ProdList
1993
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Cheng Du Micxy Chemical Co.,Ltd
Tel
028-85632863 18048500443
Fax
028-85632863
Email
sales@micxy.com
Country
China
ProdList
10476
Advantage
58
Nanjing Joyin Pharmachem Co.,Ltd
Tel
025-84670162-813 18761603731
Email
marketing@joyin.cc
Country
China
ProdList
98
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
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View Lastest Price from 2-(2-Bromoethyl)-1,3-dioxolane manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
Price
US $100.00-65.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-22
Henan Fengda Chemical Co., Ltd
Product
2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
Price
US $8.00-1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-03
Hebei Duling International Trade Co. LTD
Product
2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
Price
US $32.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2023-03-17

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