ChemicalBook > CAS DataBase List > 2-(2-Bromoethyl)-1,3-dioxolane

2-(2-Bromoethyl)-1,3-dioxolane

Product Name
2-(2-Bromoethyl)-1,3-dioxolane
CAS No.
18742-02-4
Chemical Name
2-(2-Bromoethyl)-1,3-dioxolane
Synonyms
Bromoethyldioxolane;2KG;)-1,3-dioxoL;2-(2-BromoethyL;2-(2-Bromoethyl)-1,3;2-bromo-2-(2-ethyl)dioxolane;2-(2-Bromoethyl)-1,3-dioxola;2-(2-BROMOETHYL)-1,3-DIOXOLANE;3-Bromopropanal ethylene acetal;2-(2-Bromoerthyl)-1,3-dioxolane
CBNumber
CB1156942
Molecular Formula
C5H9BrO2
Formula Weight
181.03
MOL File
18742-02-4.mol
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2-(2-Bromoethyl)-1,3-dioxolane Property

Boiling point:
68-70 °C8 mm Hg(lit.)
Density 
1.542 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.479(lit.)
Flash point:
149 °F
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly)
form 
clear liquid
Specific Gravity
1.541.542
color 
brownish-yellow
Water Solubility 
immiscible
Sensitive 
Light Sensitive
BRN 
103516
InChIKey
GGZQLTVZPOGLCC-UHFFFAOYSA-N
CAS DataBase Reference
18742-02-4(CAS DataBase Reference)
NIST Chemistry Reference
2-(2-Bromoethyl)-1,3-dioxolane(18742-02-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
2
8-9
HazardClass 
6.1
PackingGroup 
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
230995
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
96%
Packaging
10g
Price
$47.6
Updated
2025/07/31
Sigma-Aldrich
Product number
230995
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
96%
Packaging
50g
Price
$169
Updated
2025/07/31
TCI Chemical
Product number
B1132
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
>90.0%(GC)
Packaging
25g
Price
$97
Updated
2025/07/31
TCI Chemical
Product number
B1132
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
>90.0%(GC)
Packaging
100g
Price
$297
Updated
2025/07/31
TCI Chemical
Product number
B1132
Product name
2-(2-Bromoethyl)-1,3-dioxolane
Purity
>90.0%(GC)
Packaging
250g
Price
$667
Updated
2021/12/16
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2-(2-Bromoethyl)-1,3-dioxolane Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow or brown liquid

Uses

Alkylating agent for amines,1 dithianes,2 and carboximides,3 and via the Grignard reagent, aldehydes.4

Uses

2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures. It is also used as flavouring agent.

General Description

Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride affords the key organotrifluoroborate reagent.

Purification Methods

Dissolve it in pentane, wash with 5% aqueous NaHCO3, dry (Na2SO4), and evaporate. Distil the residue. [NMR: Büchi & Wüest J Org Chem 34 1122 1969, Kriesat & Gisvold J Pharm Sci 60 1250 1971, Beilstein 19/1 V 69.]

2-(2-Bromoethyl)-1,3-dioxolane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-Bromoethyl)-1,3-dioxolane Suppliers

Nanjing Intermate Technology Co., Ltd
Tel
18501091076 18501091076
Email
57715449@qq.com
Country
China
ProdList
63
Advantage
58
Zhengzhou KeYulong chemical products Co., Ltd
Tel
17319789407 17319789407
Fax
0371-53335504
Email
Keyulongchem@163.com
Country
China
ProdList
1987
Advantage
55
Nanjing Joyin Pharmachem Co.,Ltd
Tel
025-84670162-814 17354973727
Email
marketing@joyin.cc
Country
China
ProdList
141
Advantage
58
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Tel
021-60662071 18117346937
Email
18117346937@163.com
Country
China
ProdList
4993
Advantage
58
Shanghai Finechem Biotechnology Co., Ltd.
Tel
15821337685
Email
hwh-chem@163.com
Country
China
ProdList
98
Advantage
58
Henan Dongyao Pharmaceutical Technology Co., Ltd
Tel
18519331287; 18519331287
Email
1751713684@qq.com
Country
China
ProdList
220
Advantage
58
Hangzhou Aiken New Materials Co., Ltd
Tel
15258847994 15258847994
Email
1624352@qq.com
Country
China
ProdList
248
Advantage
58
Jingjiang Connect Chemical Manufacture Co., Ltd
Tel
0523-84506864 13625187466
Fax
0523-84506952
Email
sales@lvyuchem.com
Country
China
ProdList
129
Advantage
62
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from 2-(2-Bromoethyl)-1,3-dioxolane manufacturers

Hangzhou Verychem Science And Technology Co.Ltd
Product
2-(2-bromoethyl)-1,3-dioxolane 18742-02-4
Price
US $0.00-0.00/kg
Min. Order
10kg
Purity
99%min
Supply Ability
10 tons
Release date
2025-07-21
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
Price
US $100.00-65.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-22

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