2-(2-Bromoethyl)-1,3-dioxolane
- Product Name
- 2-(2-Bromoethyl)-1,3-dioxolane
- CAS No.
- 18742-02-4
- Chemical Name
- 2-(2-Bromoethyl)-1,3-dioxolane
- Synonyms
- Bromoethyldioxolane;2KG;)-1,3-dioxoL;2-(2-BromoethyL;2-(2-Bromoethyl)-1,3;2-bromo-2-(2-ethyl)dioxolane;2-(2-Bromoethyl)-1,3-dioxola;2-(2-BROMOETHYL)-1,3-DIOXOLANE;3-Bromopropanal ethylene acetal;1,3-Dioxolane, 2-(2-bromoethyl)-
- CBNumber
- CB1156942
- Molecular Formula
- C5H9BrO2
- Formula Weight
- 181.03
- MOL File
- 18742-02-4.mol
2-(2-Bromoethyl)-1,3-dioxolane Property
- Boiling point:
- 68-70 °C8 mm Hg(lit.)
- Density
- 1.542 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.479(lit.)
- Flash point:
- 149 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly)
- form
- clear liquid
- Specific Gravity
- 1.541.542
- color
- brownish-yellow
- Water Solubility
- immiscible
- Sensitive
- Light Sensitive
- BRN
- 103516
- InChIKey
- GGZQLTVZPOGLCC-UHFFFAOYSA-N
- CAS DataBase Reference
- 18742-02-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-(2-Bromoethyl)-1,3-dioxolane(18742-02-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-37/39
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 2
- F
- 8-9
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 230995
- Product name
- 2-(2-Bromoethyl)-1,3-dioxolane
- Purity
- 96%
- Packaging
- 10g
- Price
- $72.1
- Updated
- 2024/03/01
- Product number
- 230995
- Product name
- 2-(2-Bromoethyl)-1,3-dioxolane
- Purity
- 96%
- Packaging
- 50g
- Price
- $256
- Updated
- 2024/03/01
- Product number
- B1132
- Product name
- 2-(2-Bromoethyl)-1,3-dioxolane
- Purity
- >90.0%(GC)
- Packaging
- 25g
- Price
- $97
- Updated
- 2024/03/01
- Product number
- B1132
- Product name
- 2-(2-Bromoethyl)-1,3-dioxolane
- Purity
- >90.0%(GC)
- Packaging
- 100g
- Price
- $297
- Updated
- 2024/03/01
- Product number
- A11441
- Product name
- 2-(2-Bromoethyl)-1,3-dioxolane, 95%, stab. with silver
- Packaging
- 10g
- Price
- $44.65
- Updated
- 2024/03/01
2-(2-Bromoethyl)-1,3-dioxolane Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to yellow or brown liquid
Uses
Alkylating agent for amines,1 dithianes,2 and carboximides,3 and via the Grignard reagent, aldehydes.4
Uses
2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures. It is also used as flavouring agent.
General Description
Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride affords the key organotrifluoroborate reagent.
Purification Methods
Dissolve it in pentane, wash with 5% aqueous NaHCO3, dry (Na2SO4), and evaporate. Distil the residue. [NMR: Büchi & Wüest J Org Chem 34 1122 1969, Kriesat & Gisvold J Pharm Sci 60 1250 1971, Beilstein 19/1 V 69.]
2-(2-Bromoethyl)-1,3-dioxolane Preparation Products And Raw materials
Raw materials
Preparation Products
2-(2-Bromoethyl)-1,3-dioxolane Suppliers
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3576
- Advantage
- 66
- Tel
- +49-7246-3082843
- info@vladachem.de
- Country
- Germany
- ProdList
- 1860
- Advantage
- 58
View Lastest Price from 2-(2-Bromoethyl)-1,3-dioxolane manufacturers
- Product
- 2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
- Price
- US $100.00-65.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-22
- Product
- 2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
- Price
- US $8.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-03
- Product
- 2-(2-Bromoethyl)-1,3-dioxolane 18742-02-4
- Price
- US $32.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-03-17