DIPHENYLCYCLOPROPENONE
- Product Name
- DIPHENYLCYCLOPROPENONE
- CAS No.
- 886-38-4
- Chemical Name
- DIPHENYLCYCLOPROPENONE
- Synonyms
- Diphencyprone;2,3-DIPHENYLCYCLOPROP-2-EN-1-ONE;2,3-DIPHENYL-2-CYCLOPROPEN-1-ONE;1,2-DIPHENYLCYCLOPROPEN-3-ONE;opropenone;RARECHEM AQ C3 0050;Diphencyclopropenone;α,β-Carbonylstilbene;iphenylcyclopropenone;DIPHENYLCYCLOPROPENONE
- CBNumber
- CB2289953
- Molecular Formula
- C15H10O
- Formula Weight
- 206.24
- MOL File
- 886-38-4.mol
DIPHENYLCYCLOPROPENONE Property
- Melting point:
- 118-122 °C (lit.)
- Boiling point:
- 305.09°C (rough estimate)
- Density
- 1.232
- refractive index
- 1.6324 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- DMF:20.0(Max Conc. mg/mL);96.97(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);96.97(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);2.42(Max Conc. mM)
Ethanol:14.0(Max Conc. mg/mL);67.88(Max Conc. mM) - form
- Crystalline Powder
- color
- Slightly pinkish-orange to beige
- Merck
- 14,3308
- BRN
- 608049
- InChIKey
- HCIBTBXNLVOFER-UHFFFAOYSA-N
- LogP
- 1.769 (est)
- CAS DataBase Reference
- 886-38-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 8.20533
- Product name
- 2,3-Diphenyl-2-cyclopropen-1-one
- Purity
- for synthesis
- Packaging
- 1g
- Price
- $67.3
- Updated
- 2024/03/01
- Product number
- 8.20533
- Product name
- 2,3-Diphenyl-2-cyclopropen-1-one
- Purity
- for synthesis
- Packaging
- 5G
- Price
- $249
- Updated
- 2024/03/01
- Product number
- 177377
- Product name
- Diphenylcyclopropenone
- Purity
- 98%
- Packaging
- 1g
- Price
- $76.9
- Updated
- 2024/03/01
- Product number
- 177377
- Product name
- Diphenylcyclopropenone
- Purity
- 98%
- Packaging
- 5g
- Price
- $226
- Updated
- 2024/03/01
- Product number
- 8.20533
- Product name
- 2,3-Diphenyl-2-cyclopropen-1-one
- Purity
- for synthesis
- Packaging
- 500mg
- Price
- $39.4
- Updated
- 2023/01/07
DIPHENYLCYCLOPROPENONE Chemical Properties,Usage,Production
Description
Diphencyprone (DCP) is a contact sensitizing agent. Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10). It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v. Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta. Formulations containing DCP have been used in the treatment of alopecia areta.
Description
Diphencyprone is a potent contact allergen responsible for occupational contact dermatitis in chemists and dermatological staff.
Chemical Properties
slightly pinkish-orange to beige crystalline
Uses
Diphenylcyclopropenone was used in topical immunotherapy.
Definition
ChEBI: A cyclopropenone compound having phenyl substituents at the 2- and 3-positions.
General Description
Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.
Contact allergens
Diphencyprone is a potent contact allergen used in topical immunotherapy to treat some severe alopecia areata. It is responsible for occupational contact dermatitis in chemists and dermatology department staff
Purification Methods
Crystallise it from cyclohexane. UV (MeCN): max 226, 282, 297nm. [Beilstein 17 IV 1736.]
DIPHENYLCYCLOPROPENONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DIPHENYLCYCLOPROPENONE manufacturers
- Product
- DIPHENYLCYCLOPROPENONE 886-38-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2023-02-17
- Product
- DIPHENYLCYCLOPROPENONE 886-38-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24