PHOSPHORAMIDON

Product Name: PHOSPHORAMIDON
CAS No.: 36357-77-4
Chemical Name: PHOSPHORAMIDON
Synonyms: eucyl)-;yptophan;PHOSPHORAMIDON;PHOSPHORAMIDON SODIUM SALT;PHOSPHORAMIDON DISODIUM SALT DIHYDRATE;N-(A-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP-OH;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP 2NA;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP SODIUM SALT;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN
CBNumber: CB0324672
Molecular Formula: C23H34N3O10P
Formula Weight: 543.51
MOL File: 36357-77-4.mol

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PHOSPHORAMIDON Property

Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: H₂O: 1 mM Stock solution stable for 1 month at –20° C.
pka: -0.66±0.50(Predicted)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-21

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Hazard and Precautionary Statements (GHS)

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PHOSPHORAMIDON Chemical Properties,Usage,Production

Definition

ChEBI: A dipeptide isolated from the cultures of Streptomyces tanashiensis.

Enzyme inhibitor

This glycosyl phosphoramidopeptide (FWfree-acid = 543.51 g/mol; CAS 36357-77-4), also systematically named as N-(a-rhamnopyranosyloxyhydroxyphosphinyl)- L-leucyl-L-tryptophan, is a slow-binding thermolysin inhibitor (Ki = 30 nM). Note: Phosphoramidon is an epimer of talopeptin. Stock 1 mg/mL aqueous solutions of phosphoramidon are stable for one month at –20°C. Target(s): atrolysin A; atrolysin C; bacillolysin; carboxypeptidase C, weakly inhibited; coccolysin; cytosol alanyl aminopeptidase, weakly inhibited; dactylysin; endothelin-converting enzyme; endothelin-converting enzyme 2; fungalysin; gametolysin; granzyme B; Legionella metalloendopeptidase; leucyl aminopeptidase, weakly inhibited; Listeria metalloprotease Mpl; lysine carboxypeptidase, or lysine(arginine) carboxypeptidase; carboxypeptidase N; mycolysin; neprilysin, or enkephalinase, Ki = 0.8 nM; oligopeptidase O; peptidyl-dipeptidase A, or angiotensin I-converting enzyme; pitrilysin, or protease Pi; pseudolysin, or Pseudomonas aeruginosa elastase; pyruvate decarboxylase; thermolysin (27,28,41,43- 53); urethanase; vibriolysin; and Xaa-Pro aminopeptidase, or aminopeptidase P.

PHOSPHORAMIDON Preparation Products And Raw materials

Raw materials

Preparation Products

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PHOSPHORAMIDON Suppliers

China 12 Germany 1 Japan 2 Switzerland 2 United Kingdom 4 United States 14 Global 35

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
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Alabiochem Tech.Co., Ltd.

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Sichuan Kulinan Technology Co., Ltd

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Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
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Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
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Shandong Xiya Chemical Co., Ltd.

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Alabiotech Inc.

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Alpha Biopharmaceuticals Co., Ltd

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Shanghai Jizhi Biochemical Technology Co. Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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TargetMol Chemicals Inc.

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36357-77-4, PHOSPHORAMIDONRelated Search:

PHOSPHORAMIDON--N/H PHOSPHORAMIDON SODIUM SALT, FROM MICROBIAL SOURCE,PHOSPHORAMIDON PHOSPHORAMIDON NA 2H20 GLYCYL-L-TRYPTOPHAN L-ALANYL-L-TRYPTOPHAN PHOSPHORAMIDON H-LEU-TRP-OH

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT DIHYDRATE

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN (SODIUM SALT)

N-(ALPHA-RHAMNOPYRANOSYLPHOSPHONO)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT

N-[N-[[(6-deoxy-alpha-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan

N-[N-[(6-Deoxy-α-L-mannopyranosyloxy)hydroxyphosphinyl]-L-Leu-]-L-Trp-OH

L-Tryptophan,N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl-

eucyl)-

l-tryptophan,n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-l

n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-leucyl)-l-tr

yptophan

PHOSPHORAMIDON

PHOSPHORAMIDON DISODIUM SALT DIHYDRATE

PHOSPHORAMIDON SODIUM SALT

N-(A-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP 2NA

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP-OH

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP SODIUM SALT

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, 2NA

N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXY-PHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT

L-Tryptophan, N-[[(6-deoxy-α-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl-

36357-77-4

BioChemical

Biochemicals and Reagents

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Type

Enzyme Inhibitors by Enzyme

Enzyme Inhibitors

P to Q

Phosphodiesterase 3',5'-Cyclic Nucleotide

Substrate Analogs

peptides

Pepetides