ChemicalBook > CAS DataBase List > N-ACETYLTRYPTAMINE

N-ACETYLTRYPTAMINE

Product Name
N-ACETYLTRYPTAMINE
CAS No.
1016-47-3
Chemical Name
N-ACETYLTRYPTAMINE
Synonyms
Acetotryptamide;N-ACETYLTRYPTAMINE;Nb-Acetyltryptamine;N-(2-(1H-Indol-3-yl);N10-Acetyltryptamine;Acetyltryptamine, N-;TRYPTAMINE, N-ACETYL-;N-Acetyltryptamine >N-Acetyltryptamine;3-(2-Acetamidoethyl)indole
CBNumber
CB0329617
Molecular Formula
C12H14N2O
Formula Weight
202.25
MOL File
1016-47-3.mol
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N-ACETYLTRYPTAMINE Property

Melting point:
74.0 to 78.0 °C
Boiling point:
200°C/0.2mmHg(lit.)
Density 
1.164±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: soluble
form 
powder
pka
16.48±0.46(Predicted)
color 
White to Light yellow to Light orange
λmax
290nm(MeOH)(lit.)
CAS DataBase Reference
1016-47-3
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2933.99.8290
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S307483
Product name
N-(2-(1H-INDOL-3-YL)-ETHYL)-ACETAMIDE
Purity
Aldrich
Packaging
25mg
Price
$172
Updated
2023/01/07
TCI Chemical
Product number
A2685
Product name
N-Acetyltryptamine
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$164
Updated
2025/07/31
TCI Chemical
Product number
A2685
Product name
N-Acetyltryptamine
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$546
Updated
2023/01/07
Cayman Chemical
Product number
18605
Product name
N-acetyl Tryptamine
Purity
≥98%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
18605
Product name
N-acetyl Tryptamine
Purity
≥98%
Packaging
10mg
Price
$87
Updated
2024/03/01
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N-ACETYLTRYPTAMINE Chemical Properties,Usage,Production

Description

The Argentinian medicinal plant Prosopsis nigra contains this alkaloid of the simple indole type which has recently been isolated and characterized. It may be a direct precursor in the biosynthesis of the {:l-carboline bases.

Description

N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.

Uses

N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.

Definition

ChEBI: A tryptamine compound having an acetyl substituent attached to the side-chain amino function.

Enzyme inhibitor

This partial receptor agonist (FW = 202.26 g/mol; CAS 1016-47-3; Soluble to 100 mM in DMSO) is a melatonin (or 5-methoxy-N-acetyltryptamine) mimic and is more potent than melatonin in inhibiting dopamine release fom presynaptic melatonin receptor site of rabbit retina labeled in vitro with [3H]dopamine.

storage

Room temperature

References

Moro, Graziano, Coussio, Phytochern., 14,827 (1975)

N-ACETYLTRYPTAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1016-47-3, N-ACETYLTRYPTAMINERelated Search:

AC-TRP-OET AC-TRP-NH2 Melatonine 5-Hydroxy-N-acetyltryptamine N-Acetyl-DL-tryptophan BZ-TRP-OH 5-METHOXYCARBONYLAMINO-N-ACETYLTRYPTAMINE Tryptamine Z-HIS-PHE-TRP-OET AC-TRP-ONP 3-(2-FURYL)ACRYLOYL-L-TRYPTOPHAN METHYL ESTER Z-ALA-TRP-OH GLYCYL-DL-TRYPTOPHAN AC-TRP-OME H-LEU-TRP-LEU-OH 4-CHLOROBENZOYL-L-TRYPTOPHAN CALCIUM SALT Z-TRP-TRP-OH H-GLY-TRP-GLY-OH

  • Acetotryptamide
  • N-[2-(1H-Indol-3-yl)-ethyl]-acetamide
  • 3-(2-N-ACETYLAMINOETHYL)INDOLE
  • 3-[2-(Acetylamino)ethyl]-1H-indole
  • N-Acetyl-1H-indole-3-ethaneamine
  • N-[2-(1H-indol-3-yl)ethyl]ethanamide
  • N-(2-(1H-Indol-3-yl)
  • <i>N</i>-Acetyltryptamine
  • N-ACETYLTRYPTAMINE
  • TRYPTAMINE, N-ACETYL-
  • Acetamide,N-(2-indol-3-ylethyl)-
  • Acetamide,N-[2-(1H-indol-3-yl)ethyl]-
  • N-Acetyltryptamine &gt
  • 3-(2-Acetamidoethyl)indole
  • N10-Acetyltryptamine,N ACETYLTRYPTAMINE,inhibit,N-Acetyltryptamine,Nω-Acetyltryptamine,Nb-Acetyltryptamine,Inhibitor,NACETYLTRYPTAMINE,Melatonin Receptor
  • N10-Acetyltryptamine
  • Nb-Acetyltryptamine
  • Acetyltryptamine, N-
  • N-ACETYLTRYPTAMINE, 10 mM in DMSO
  • 1016-47-3