N-ACETYLTRYPTAMINE
- Product Name
- N-ACETYLTRYPTAMINE
- CAS No.
- 1016-47-3
- Chemical Name
- N-ACETYLTRYPTAMINE
- Synonyms
- Acetotryptamide;N-ACETYLTRYPTAMINE;Nb-Acetyltryptamine;N-(2-(1H-Indol-3-yl);N10-Acetyltryptamine;TRYPTAMINE, N-ACETYL-;N-Acetyltryptamine >N-Acetyltryptamine;3-(2-Acetamidoethyl)indole;3-(2-N-ACETYLAMINOETHYL)INDOLE
- CBNumber
- CB0329617
- Molecular Formula
- C12H14N2O
- Formula Weight
- 202.25
- MOL File
- 1016-47-3.mol
N-ACETYLTRYPTAMINE Property
- Melting point:
- 74.0 to 78.0 °C
- Boiling point:
- 200°C/0.2mmHg(lit.)
- Density
- 1.164±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- alcohol: soluble
- form
- powder
- pka
- 16.48±0.46(Predicted)
- color
- White to Light yellow to Light orange
- λmax
- 290nm(MeOH)(lit.)
- CAS DataBase Reference
- 1016-47-3
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2933.99.8290
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363Wash contaminated clothing before reuse.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- S307483
- Product name
- N-(2-(1H-INDOL-3-YL)-ETHYL)-ACETAMIDE
- Purity
- Aldrich
- Packaging
- 25mg
- Price
- $172
- Updated
- 2023/01/07
- Product number
- A2685
- Product name
- N-Acetyltryptamine
- Purity
- >98.0%(HPLC)
- Packaging
- 25mg
- Price
- $164
- Updated
- 2024/03/01
- Product number
- A2685
- Product name
- N-Acetyltryptamine
- Purity
- >98.0%(HPLC)
- Packaging
- 100mg
- Price
- $546
- Updated
- 2023/01/07
- Product number
- 18605
- Product name
- N-acetyl Tryptamine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 18605
- Product name
- N-acetyl Tryptamine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $87
- Updated
- 2024/03/01
N-ACETYLTRYPTAMINE Chemical Properties,Usage,Production
Description
The Argentinian medicinal plant Prosopsis nigra contains this alkaloid of the simple indole type which has recently been isolated and characterized. It may be a direct precursor in the biosynthesis of the {:l-carboline bases.
Description
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.
Uses
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.
Definition
ChEBI: A tryptamine compound having an acetyl substituent attached to the side-chain amino function.
Enzyme inhibitor
This partial receptor agonist (FW = 202.26 g/mol; CAS 1016-47-3; Soluble to 100 mM in DMSO) is a melatonin (or 5-methoxy-N-acetyltryptamine) mimic and is more potent than melatonin in inhibiting dopamine release fom presynaptic melatonin receptor site of rabbit retina labeled in vitro with [3H]dopamine.
storage
Room temperature
References
Moro, Graziano, Coussio, Phytochern., 14,827 (1975)