BENZIODARONE

Product Name: BENZIODARONE
CAS No.: 68-90-6
Chemical Name: BENZIODARONE
Synonyms: l2329;Dilaf;algocor;Vasilar;carofam;Corofam;amplivix;cardivix;2329labaz;Retrangor
CBNumber: CB0330990
Molecular Formula: C17H12I2O3
Formula Weight: 518.08
MOL File: 68-90-6.mol

More

Less

BENZIODARONE Property

Melting point:: 167°
Density: 1.9173 (estimate)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form: Solid
color: Beige
Water Solubility: 5.881mg/L(20 ºC)
CAS DataBase Reference: 68-90-6

More

Less

Safety

HS Code: 2906.19.5000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: E1290
Product name: Benziodarone
Purity: >98.0%(GC)
Packaging: 1g
Price: $121
Updated: 2024/03/01

TCI Chemical

Product number: E1290
Product name: Benziodarone
Purity: >98.0%(GC)
Packaging: 5g
Price: $425
Updated: 2024/03/01

TRC

Product number: B197860
Product name: Benziodarone
Packaging: 10mg
Price: $150
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010003
Product name: BENZIODARONE
Purity: 95.00%
Packaging: 1MG
Price: $157.5
Updated: 2021/12/16

AK Scientific

Product number: 0208BA
Product name: Benziodarone
Packaging: 1g
Price: $225
Updated: 2021/12/16

More

Less

BENZIODARONE Chemical Properties,Usage,Production

Originator

Amplivix,Sigma-Tau

Uses

Benziodarone is a uricosuric drug,it is used to effectively to control hyperuricemia in renal transplantation.

Definition

ChEBI: Benziodarone is an aromatic ketone.

Manufacturing Process

The starting product 2-ethyl-3-benzofuranyl p-hydroxyphenyl ketone (benzaron) was prepared in 4 steps:
1. First step was a reaction of salicylic aldehyde with chloroacetone to produce 2-acetyl-1-benzofuran.
2. It was reduced by hydrazine hydrate in an alkaline medium by process of Hyuang-Minlon, J.A.C.S., 1946, 68, 2487 to give 2-ethyl-1-benzofurane.
3. 2-Ethyl-3-(4-methoxybenzoyl)-1-benzofuran was obtained from 2-ethyl-1- benzofuran and 4-methoxy-benzoylchloride in a presence of tin tetrachloride. 4. It was heated with pyridine hydrochloride at 200°-220°C to give 2-ethyl-3- benzofuranyl p-hydroxyphenyl ketone (benzaron) as described in N.P.B.Hoi, C.Beaudet; US Patent No. 3,012,042; Dec. 5, 1961.
Benzaron (1 part) was dissolved in a very slight excess of 3% caustic soda. To this solution is gradually added a slight excess of iodine dissolved in a 25% aqueous solution of potassium iodide. The resultant solution is acidified with a 20% solution of sodium bisulphite, centrifuged, washed with water and then recrystallized in acetic acid to give of 2-ethyl-3-benzofuranyl 4-hydroxy-3,5- diiodophenyl ketone. MP: 167°C.

Therapeutic Function

Coronary vasodilator, Uricosuric

Safety Profile

A poison bj7 intraperitoneal and intravenous routes. Moderately toxic by ingestion. A flammable liquid. When heated to decomposition it emits toxic vapors of I-.

BENZIODARONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BENZIODARONE Suppliers

Americas 1 Canada 1 China 24 Europe 1 France 1 India 1 Japan 1 United Kingdom 5 United States 8 Global 43

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

TCI Chemicals

Tel: 021-67121386, 800-988-0390
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 5391
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15352
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9974
Advantage: 58

CHG Opto-Electronic Corporation Limited

Tel: 2537653158 16621191650
Fax: QQ 2537653158
Email: 2537653158@qq.com
Country: China
ProdList: 7167
Advantage: 58

Changzhou Furuisi Biotechnology Co., Ltd

Tel: 0519-85524369
Email: 3477467573@qq.com
Country: China
ProdList: 8617
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 15229059051
Email: 1027@dideu.com
Country: China
ProdList: 10011
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725 17717813675;
Email: malulu@leyan.com
Country: China
ProdList: 39988
Advantage: 58

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 73043
Advantage: 58

Shanghai Yubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 344843571@qq.com
Country: CHINA
ProdList: 6318
Advantage: 58

Beijing Fubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: info@f-biology.com
Country: CHINA
ProdList: 6025
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shxiyuanbio@163.com
Country: CHINA
ProdList: 6906
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6936
Advantage: 58

Beijing Baiao Innovation Technology Co., Ltd.

Tel: --
Fax: --
Email: 3007606172@qq.com
Country: CHINA
ProdList: 6002
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6973
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Lanospharma Laboratories Co.,Ltd

Tel: --
Fax: --
Email: sales@lanospharma.com
Country: China
ProdList: 6329
Advantage: 56

68-90-6, BENZIODARONERelated Search:

Bisoprolol Amiodarone hydrochloride 2-BUTYL-3-(3,5-DIIODO-4-(OXYACETIC ACID ETHYL ESTER)-BENZOYL)-BENZOFURAN 2-Butyl-3-(3,5-Diiodo-4-hydroxy benzoyl) benzofuran Desethylamiodarone Amiodarone BENZIODARONE

BENZIODARONE

2-Ethyl-3-benzofuranyl 4-hydroxy-3,5-diiodophenyl ketone

Vasilar

2329labaz

2-ethyl-3-(3’,5’-diiodo-4’-hydroxybenzoyl)-cumarone

3-(3,5-diiodo-4-hydroxybenzoyl)-2-ethyl-benzofura

3,5-diiodo-4-hydroxyphenyl2-ethyl-3-benzofuranylketone

aethyl-2-(3’,5’-dijod-4’-oxybenzoyl)-3cumaron

algocor

amplivix

benziodaron

cardivix

carofam

coronal-crinos

dilafurane

dila-vasal

ketone,3,5-diiodo-4-hydroxyphenyl2-ethyl-3-benzofuranyl

l2329

Benzoiodarone

Corofam

Retrangor

(2-ethyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone

(2-ethyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodo-phenyl)methanone

(2-ethylbenzofuran-3-yl)-(4-hydroxy-3,5-diiodo-phenyl)methanone

(2-Ethyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)Methanone

2-Ethyl-3-(3,5-diiodo-4-hydroxybenzoyl)-3-couMarone

2-Ethyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran

Dilaf

NSC 82133

Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)-

2-Ethyl-3-(4-hydroxy-3,5-diiodobenzoyl)benzofuran

Dilacoron

68-90-6

C17H12I2O3

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals