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Leniolisib

Product Name
Leniolisib
CAS No.
1354690-24-6
Chemical Name
Leniolisib
Synonyms
CS-2818;CDZ 173;Leniolisib;leniolisib(CDZ 173);CDZ173;CDZ-173;CDZ 173;Rupatadine Impurity 2-d8;inhibit,Inhibitor,Phosphoinositide 3-kinase,Leniolisib,PI3K,CDZ-173,CDZ 173;(S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one;1-Propanone, 1-[(3S)-3-[[5,6,7,8-tetrahydro-6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]pyrido[4,3-d]pyrimidin-4-yl]amino]-1-pyrrolidinyl]-
CBNumber
CB03311734
Molecular Formula
C21H25F3N6O2
Formula Weight
450.46
MOL File
1354690-24-6.mol
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Leniolisib Property

storage temp. 
Store at -20°C
solubility 
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:71.67(Max Conc. mg/mL);159.09(Max Conc. mM)
Ethanol:16.5(Max Conc. mg/mL);36.63(Max Conc. mM)
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28078
Product name
Leniolisib
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
28078
Product name
Leniolisib
Packaging
25mg
Price
$770
Updated
2024/03/01
Cayman Chemical
Product number
28078
Product name
Leniolisib
Packaging
5mg
Price
$227
Updated
2024/03/01
Cayman Chemical
Product number
28078
Product name
Leniolisib
Packaging
10mg
Price
$403
Updated
2024/03/01
ChemScene
Product number
CS-7524
Product name
Leniolisib
Purity
99.25%
Packaging
10mg
Price
$350
Updated
2021/12/16
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Leniolisib Chemical Properties,Usage,Production

Biological Activity

Leniolisib (CDZ 173) is a potent and selective PI3Kδ inhibitor with IC50s of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> PI3Kβ
(Cell-free assay)
TargetValue
PI3Kδ
(Cell-free assay)		 0.011 μM
PI3Kα
(Cell-free assay)		 0.244 μM
0.424 μM
DNA-PK
()		 0.88 μM
DNA-PK
(Cell-free assay)		 0.88 μM

Leniolisib Preparation Products And Raw materials

Raw materials

Preparation Products

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Leniolisib Suppliers

China 60 United States 7 Global 67
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65

1354690-24-6, LeniolisibRelated Search:


  • Leniolisib
  • CDZ173;CDZ-173;CDZ 173
  • CS-2818
  • leniolisib(CDZ 173)
  • CDZ 173
  • 1-Propanone, 1-[(3S)-3-[[5,6,7,8-tetrahydro-6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]pyrido[4,3-d]pyrimidin-4-yl]amino]-1-pyrrolidinyl]-
  • (S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one
  • inhibit,Inhibitor,Phosphoinositide 3-kinase,Leniolisib,PI3K,CDZ-173,CDZ 173
  • Rupatadine Impurity 2-d8
  • 1354690-24-6
  • C21H25F3N6O2