Formononetin
- Product Name
- Formononetin
- CAS No.
- 485-72-3
- Chemical Name
- Formononetin
- Synonyms
- 7-hydroxy-3-(4-Methoxyphenyl)-4H-chroMen-4-one;ForMonentin;Formononetine;Formononetin (50 mg);Myconate;Flavosil;Mycotech;biocanin;NSC 93360;NEOCHANIN
- CBNumber
- CB0331896
- Molecular Formula
- C16H12O4
- Formula Weight
- 268.26
- MOL File
- 485-72-3.mol
Formononetin Property
- Melting point:
- 256-260 °C
- Boiling point:
- 331.43°C (rough estimate)
- Density
- 1.1529 (rough estimate)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.4350 (estimate)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO (up to 100 mg/ml).
- form
- Powder
- pka
- 6.99±0.20(Predicted)
- color
- White to light beige
- λmax
- 300nm(EtOH)(lit.)
- Merck
- 14,4244
- BRN
- 237979
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
- InChIKey
- HKQYGTCOTHHOMP-UHFFFAOYSA-N
- LogP
- 1.7 at 25℃
- CAS DataBase Reference
- 485-72-3(CAS DataBase Reference)
- EPA Substance Registry System
- 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)- (485-72-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-36
- WGK Germany
- 3
- RTECS
- DJ3100114
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 47752
- Product name
- Formononetin
- Purity
- ≥99.0% (TLC)
- Packaging
- 5mg
- Price
- $137
- Updated
- 2025/07/31
- Product number
- 47752
- Product name
- Formononetin
- Purity
- ≥99.0% (TLC)
- Packaging
- 25mg
- Price
- $503
- Updated
- 2025/07/31
- Product number
- 344215
- Product name
- Formononetin
- Purity
- A phytoestrogenic isoflavone found in soy-based foods.
- Packaging
- 5mg
- Price
- $98.6
- Updated
- 2025/07/31
- Product number
- 1286060
- Product name
- Formononetin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 50mg
- Price
- $1050
- Updated
- 2025/07/31
- Product number
- F0868
- Product name
- Formononetin
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $120
- Updated
- 2025/07/31
Formononetin Chemical Properties,Usage,Production
Description
Formononetin (485-72-3) is a naturally occurring isoflavone isolated from Astragalus and other plants. Increases adipocyte thermogenesis by modulating PPARγ activity.1?Activates AMP-activated protein kinase/β-catenin signaling to inhibit adipogenesis.2?Accelerates wound repair by increasing expression of Egr-1 transcription factor.3?Potential cancer chemopreventive and chemotherapeutic.4?Provides neuroprotection against traumatic brain injury by inhibition of neuroinflammation in a rat model.5
Chemical Properties
off-white powder
Uses
An isoflavone found in a variety of plants. When metabolized in the rumen this compound transforms into a potent estrogen.
Uses
Formononetin is an isoflavone found as one of the main plant estrogens in animal feed. When metabolized in the rumen this compound transforms into a potent estrogen.
Uses
Formononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein . It acts as an agonist of the aryl hydrocarbon receptor with an EC50 value of 0.13 μM. Formononetin has been reported to possess antitumor and antiviral activity.
Definition
ChEBI: Formononetin is a member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'. It has a role as a phytoestrogen and a plant metabolite. It is a member of 7-hydroxyisoflavones and a member of 4'-methoxyisoflavones. It is functionally related to a daidzein. It is a conjugate acid of a formononetin(1-).
General Description
Formononetin belongs to the isoflavones class of polyphenols.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Isoflavone found in red clover. Effective against Giardia lamblia infection, at least partially by inducing detachment of trophozoites from intestinal mucosa.
References
[1] TAO NIE. The natural compound, formononetin, extracted from Astragalus membranaceus increases adipocyte thermogenesis by modulating PPARγ activity[J]. British Journal of Pharmacology, 2018, 175 9: 1439-1450. DOI:10.1111/bph.14139
[2] JYOTI GAUTAM. Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss.[J]. British Journal of Nutrition, 2017, 117 5: 645-661. DOI:10.1017/s0007114517000149
[3] JEONG-EUN HUH . Formononetin accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERK and p38 MAPK pathways[J]. International immunopharmacology, 2011, 11 1: Pages 46-54. DOI:10.1016/j.intimp.2010.10.003
[4] SAMANTHA KAH LING ONG. Focus on Formononetin: Anticancer Potential and Molecular Targets.[J]. Cancers, 2019. DOI:10.3390/cancers11050611
[5] ZHENGZHAO LI . Neuroprotective effect of formononetin against TBI in rats via suppressing inflammatory reaction in cortical neurons[J]. Biomedicine & Pharmacotherapy, 2018, 106: Pages 349-354. DOI:10.1016/j.biopha.2018.06.041
Formononetin Preparation Products And Raw materials
Raw materials
Preparation Products
Formononetin Suppliers
- Tel
- 18266960953
- 907697096@qq.com
- Country
- China
- ProdList
- 3033
- Advantage
- 58
- Tel
- 025-52794219 13140719234
- 2498234449@qq.com
- Country
- China
- ProdList
- 124
- Advantage
- 58
- Tel
- 18805194892
- 2727751293@qq.com
- Country
- China
- ProdList
- 170
- Advantage
- 58
- Tel
- 18635070697
- 1050193820@qq.com
- Country
- China
- ProdList
- 33
- Advantage
- 58
- Tel
- 0576-88203651 15967007102
- 103858443@qq.com
- Country
- China
- ProdList
- 255
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6003
- Advantage
- 61
View Lastest Price from Formononetin manufacturers
- Product
- Formononetin 485-72-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1
- Release date
- 2025-09-08
- Product
- Formononetin 485-72-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000kg
- Release date
- 2025-04-24
- Product
- Formononetin 485-72-3
- Price
- US $3.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-09-10