Tofacitinib Impurity 45

Product Name: Tofacitinib Impurity 45
CAS No.: 2407039-29-4
Chemical Name: Tofacitinib Impurity 45
Synonyms: CP-690550 N-Hydroxyl;Tofacitinib Impurity 45;Tofacitinib Impurity 172;(3R,4R)-3-[(7-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)methylamino]-4-methyl-β-oxo-1-piperidinepropanenitrile;1-Piperidinepropanenitrile, 3-[(7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)methylamino]-4-methyl-β-oxo-, (3R,4R)-
CBNumber: CB03360222
Molecular Formula: C16H20N6O2
Formula Weight: 328.38
MOL File: 2407039-29-4.mol

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Tofacitinib Impurity 45 Property

Melting point:: >144°C (dec.)
Boiling point:: 625.5±65.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 6.04±0.60(Predicted)
color: Light Brown to Brown

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Hazard and Precautionary Statements (GHS)

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Tofacitinib Impurity 45 Chemical Properties,Usage,Production

Uses

CP-690550 N-Hydroxyl is an impurity of CP-690550 (C781350), a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis.

Tofacitinib Impurity 45 Preparation Products And Raw materials

Raw materials

Preparation Products

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Tofacitinib Impurity 45 Suppliers

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2407039-29-4, Tofacitinib Impurity 45Related Search:

(3R,4R)-N,1,4-trimethyl-N-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidin-3-amine N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Tofacitinib Impurity Tofacitinib Impurity 36 6,7-Dihydro-N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-5H-pyrrolo[2,3-d]pyrimidin-4-amine 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]- 1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, ethyl ester, (3R,4R)- 3-((3R,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanaMide 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Tofacitinib Impurity butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate 3-PiperidinaMine, 1-acetyl-N,4-diMethyl-N-1H-pyrrolo[2,3-d]pyriMidin-4-yl-, (3R,4R)- (9CI) N-(2,6-dimethylphenyl)-2-((2,6-dimethylphenyl)amino)acetamide (3S,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine 1-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE DIHYDROCHLORIDE Tofacitinib Related Compound Tofacitinib Impurity 2

Tofacitinib Impurity 45

CP-690550 N-Hydroxyl

(3R,4R)-3-[(7-Hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)methylamino]-4-methyl-β-oxo-1-piperidinepropanenitrile

1-Piperidinepropanenitrile, 3-[(7-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-4-yl)methylamino]-4-methyl-β-oxo-, (3R,4R)-

Tofacitinib Impurity 172

2407039-29-4