Cholesteryl hemisuccinate

Product Name: Cholesteryl hemisuccinate
CAS No.: 1510-21-0
Chemical Name: Cholesteryl hemisuccinate
Synonyms: CHOLESTERYL HYDROGEN SUCCINATE;cholesterylsuccinate;Cholesterol Succinate;CHOLESTERYL HEMISUCCINATE;MONO-CHOLESTERYL-SUCCINATE;CHOLESTEROL HYDROGEN SUCCINATE;5-CHOLESTEN-3β-OL HEMISUCCINATE;Cholesterol Hydrogen Succinate >5-CHOLESTEN-3-BETA-OL HEMISUCCINATE;SUCCINIC ACID MONOCHOLESTEROL ESTER
CBNumber: CB0336321
Molecular Formula: C31H50O4
Formula Weight: 486.73
MOL File: 1510-21-0.mol

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Cholesteryl hemisuccinate Property

Melting point:: 178 °C
Boiling point:: 586.0±43.0 °C(Predicted)
Density: 1.06±0.1 g/cm3(Predicted)
refractive index: -34 ° (C=2, CHCl3)
storage temp.: -20°C
solubility: Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
form: Solid
pka: 4.40±0.17(Predicted)
color: White to Off-White
InChIKey: WLNARFZDISHUGS-BLYFUZNHSA-N
LogP: 10.708 (est)
CAS DataBase Reference: 1510-21-0(CAS DataBase Reference)

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Safety

WGK Germany: 3
HS Code: 29171900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C6512
Product name: Cholesteryl hemisuccinate
Packaging: 5g
Price: $271
Updated: 2024/03/01

Sigma-Aldrich

Product number: C6512
Product name: Cholesteryl hemisuccinate
Packaging: 25g
Price: $897
Updated: 2024/03/01

Cayman Chemical

Product number: 25698
Product name: Cholesteryl Hemisuccinate
Purity: ≥95%
Packaging: 1g
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 25698
Product name: Cholesteryl Hemisuccinate
Purity: ≥95%
Packaging: 5g
Price: $183
Updated: 2024/03/01

Cayman Chemical

Product number: 25698
Product name: Cholesteryl Hemisuccinate
Purity: ≥95%
Packaging: 10g
Price: $341
Updated: 2024/03/01

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Cholesteryl hemisuccinate Chemical Properties,Usage,Production

Description

Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity. It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively. Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.

Uses

Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages.

Definition

ChEBI: Cholesteryl hemisuccinate is a dicarboxylic acid monoester resulting from the formal condensation of the hydroxy group of cholesterol with one of the carboxy groups of succinic acid. A detergent that is often used to replace cholesterol in protein crystallography, biochemical studies of proteins, and pharmacology. It has a role as a detergent. It is a cholestane ester, a dicarboxylic acid monoester and a hemisuccinate. It is functionally related to a cholesterol.

General Description

Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.

Biochem/physiol Actions

CHEMS can help to maintain the stability of dioleoylphosphatidylethanolamine (DOPE). This amphipathic lipid is used in mixtures with dioleoylphosphatidylethanolamine (DOPE) to form ′pH sensitive′ fusogenic vesicles. It can control cell growth.

Cholesteryl hemisuccinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cholesteryl hemisuccinate Suppliers

China 106 Europe 2 Germany 2 India 3 Japan 1 Sweden 1 Switzerland 1 United Kingdom 6 United States 22 Global 144

Carbosynth

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Tokyo Chemical Industry UK Ltd.

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Sequoia Research Products Ltd

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CARBONE SCIENTIFIC CO.,LTD

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VWR International

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Sequoia Research Products Ltd.

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View Lastest Price from Cholesteryl hemisuccinate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Cholesteryl hemisuccinate 1510-21-0
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-05

Xian confluore Biological Technology Co., Ltd.

Product: CHEMS 1510-21-0
Price: US $0.00/g
Min. Order: 100g
Purity: >95.00%
Supply Ability: 100g
Release date: 2024-04-01

Henan Aochuang Chemical Co.,Ltd.

Product: Cholesteryl hemisuccinate 1510-21-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-09

1510-21-0, Cholesteryl hemisuccinateRelated Search:

6alpha-Methylprednisolone sodium succinate Disodium succinate Hydrogen Hydrogen Sulfide iron succinate CHLOROPHOSPHONAZO III Dimethyl succinate Succinic acid Cholesteryl oleate HYDROGEN CYANIDE Hydrogen peroxide Cholesterol (-)-Cholesterol sulfo-NHS succinate CHOLESTERYL HEMISUCCINATE F & D VERSION&,CHOLESTERYL HEMISUCCINATE TRIS,CHOLESTERYL HEMISUCCINATE TRIS SALT,CHOLESTERYL HYDROGEN SUCCINATE TRIS SALT (-)-Cholesterol NHS succinate hydrogen fluoride 5-CHOLESTENE Cholesteryl hemisuccinate

3β-(1,4-Dioxo-4-hydroxybutoxy)cholesta-5-ene

Butanedioic acid hydrogen 1-(cholest-5-en-3β-yl) ester

Succinic acid 1-(3β-cholesteryl) ester

Succinic acid hydrogen 3β-cholesteryl ester

Succinic acid hydrogen cholest-5-en-3β-yl ester

Cholest-5-en-3-ol (3b)-, 3-(hydrogen butanedioate)

CHOLESTEROL HYDROGEN SUCCINATE

CHOLESTERYL HYDROGEN SUCCINATE

CHOLESTERYL HEMISUCCINATE

3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE

5-CHOLESTER-3BETA-YL HYDROGEN SUCCINATE

5-CHOLESTEN-3-BETA-OL HEMISUCCINATE

5-CHOLESTEN-3BETA-OL 3-HEMISUCCINATE

SUCCINIC ACID MONOCHOLESTEROL ESTER

MONO-CHOLESTERYL-SUCCINATE

cholesterylsuccinate

cholesteryl hemisuccinate free acid

Cholesteryl hydrogen succinate Cholesteryl hemisuccinate

cholest-5-en-3beta-yl hydrogen succinate

Cholesterol Hydrogen Succinate &gt

Cholest-5-en-3-ol (3β)-, 3-(hydrogen butanedioate)

Cholesterol Succinate

6-Amino-2,4-dichloro-26-methylphenol&hydrochloride

Cholest-5-en-3-ol (3β)-, 3-(hydrogen butanedioate)

5-CHOLESTEN-3β-OL HEMISUCCINATE

1510-21-0

C31H50O4

Cholesteryl Compounds (Liquid Crystals)

Functional Materials

Liquid Crystals & Related Compounds