Biotin-PEG2-NH-Boc

Product Name: Biotin-PEG2-NH-Boc
CAS No.: 175885-18-4
Chemical Name: Biotin-PEG2-NH-Boc
Synonyms: Biotin-PEG2-NH-Boc;Biotin-PEG2-CH2CH2NH-Boc;N-Boc-N'-biotinyl-3,6-dioxaoctane-1,8-diamine;tert-Butyl (2-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)ethyl)carbamate;5,8-Dioxa-2,11-diazahexadecanoic acid, 16-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-12-oxo-, 1,1-dimethylethyl ester
CBNumber: CB03363874
Molecular Formula: C21H38N4O6S
Formula Weight: 474.61
MOL File: 175885-18-4.mol

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Biotin-PEG2-NH-Boc Property

storage temp.: 2-8°C
solubility: Soluble in Water, DMSO, DMF, DCM
form: Solid
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23412
Product name: Biotin-PEG2-NH-Boc
Purity: 97%
Packaging: 500mg
Price: $460
Updated: 2021/12/16

Ambeed

Product number: A764992
Product name: BIotin-peg2-nh-boc
Purity: 95%
Packaging: 100mg
Price: $221
Updated: 2021/12/16

Ambeed

Product number: A764992
Product name: BIotin-peg2-nh-boc
Purity: 95%
Packaging: 250mg
Price: $383
Updated: 2021/12/16

Ambeed

Product number: A764992
Product name: BIotin-peg2-nh-boc
Purity: 95%
Packaging: 1g
Price: $880
Updated: 2021/12/16

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Biotin-PEG2-NH-Boc Chemical Properties,Usage,Production

Description

Biotin-PEG2-NH-Boc is a PEG linker with biotin and Boc protected amine moieties. The biotin group is used for the conjugation of proteins and can also be used for labeling. Boc can be removed under acidic condition.

Uses

Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

Biotin-PEG2-NH-Boc Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-PEG2-NH-Boc Suppliers

China 35 United States 4 Global 39

Taizhou GreenChem Pharmaceutical Co., Ltd.

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Career Henan Chemica Co

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175885-18-4, Biotin-PEG2-NH-BocRelated Search:

Biotin-PEG5-NH-Boc EZ-LINK (TM) PFP-BIOTIN, 50 MG Biotin-PEG7-Amine Biotin-PEG2-Hydrazide 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(2-hydroxyethoxy)ethyl]-2-oxo-, (3aS,4S,6aR)- Biotin-PEG5-azide Biotin-peg3-alcohol Biotin-PEG3-Me-Tet Biotin-PEG3-t-butyl ester 21-[D(+)-Biotinylamino]-4,7,10,13,16,19-hexaoxaheneicosanoic acid 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, 1,1-dimethylethyl ester Biotin-PEG3-N3 (+)-Biotin-PEG6-NHS Ester 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- Biotin-PEG4-Silane Biotin-PEG4-PFP ester Biotin-PEG3-oxyamine

Biotin-PEG2-NH-Boc

tert-Butyl (2-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)ethyl)carbamate

5,8-Dioxa-2,11-diazahexadecanoic acid, 16-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-12-oxo-, 1,1-dimethylethyl ester

N-Boc-N'-biotinyl-3,6-dioxaoctane-1,8-diamine

Biotin-PEG2-CH2CH2NH-Boc

175885-18-4

C21H38N4O6S