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t-Butoxycarbonyl-PEG5-sulfonic acid

Product Name
t-Butoxycarbonyl-PEG5-sulfonic acid
CAS No.
1817735-28-6
Chemical Name
t-Butoxycarbonyl-PEG5-sulfonic acid
Synonyms
Butoxycarbonyl-PEG5-sulfonic acid;t-Butoxycarbonyl-PEG5-sulfonic acid;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-sulfo-, 1-(1,1-dimethylethyl) ester
CBNumber
CB03364028
Molecular Formula
C17H34O10S
Formula Weight
430.51
MOL File
1817735-28-6.mol
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t-Butoxycarbonyl-PEG5-sulfonic acid Property

Density 
1.185±0.06 g/cm3(Predicted)
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
1.34±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22882
Product name
t-Butoxycarbonyl-PEG5-sulfonicacid
Purity
95%
Packaging
1g
Price
$1200
Updated
2021/12/16
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t-Butoxycarbonyl-PEG5-sulfonic acid Chemical Properties,Usage,Production

Description

t-Butoxycarbonyl-PEG5-sulfonic acid is a PEG linker containing a t-butyl protecting group and a sulfonic acid moiety. t-butyl can be deprotected under acidic conditions. Sulfonic acid groups can participate in esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Butoxycarbonyl-PEG5-sulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Butoxycarbonyl-PEG5-sulfonic acid Suppliers

Jinan elephant international trading co., LTD
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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Zhengzhou Akem Chemical Co., Ltd
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-80514535 19917294565
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Jilin Chinese Academy of Sciences-yanshen Technology
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TargetMol Chemicals Inc.
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15002134094
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China
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Henan Mengtai Pharmaceutical Technology Co., Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology
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info@chemextension.com
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1817735-28-6, t-Butoxycarbonyl-PEG5-sulfonic acidRelated Search:


  • t-Butoxycarbonyl-PEG5-sulfonic acid
  • Butoxycarbonyl-PEG5-sulfonic acid
  • 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-sulfo-, 1-(1,1-dimethylethyl) ester
  • 1817735-28-6
  • C17H34O10S