ChemicalBook > CAS DataBase List > t-Butoxycarbonyl-PEG5-sulfonic acid
t-Butoxycarbonyl-PEG5-sulfonic acid
- Product Name
- t-Butoxycarbonyl-PEG5-sulfonic acid
- CAS No.
- 1817735-28-6
- Chemical Name
- t-Butoxycarbonyl-PEG5-sulfonic acid
- Synonyms
- Butoxycarbonyl-PEG5-sulfonic acid;t-Butoxycarbonyl-PEG5-sulfonic acid;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-sulfo-, 1-(1,1-dimethylethyl) ester
- CBNumber
- CB03364028
- Molecular Formula
- C17H34O10S
- Formula Weight
- 430.51
- MOL File
- 1817735-28-6.mol
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t-Butoxycarbonyl-PEG5-sulfonic acid Property
- Density
- 1.185±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 1.34±0.50(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22882
- Product name
- t-Butoxycarbonyl-PEG5-sulfonicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $1200
- Updated
- 2021/12/16
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t-Butoxycarbonyl-PEG5-sulfonic acid Chemical Properties,Usage,Production
Description
t-Butoxycarbonyl-PEG5-sulfonic acid is a PEG linker containing a t-butyl protecting group and a sulfonic acid moiety. t-butyl can be deprotected under acidic conditions. Sulfonic acid groups can participate in esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Butoxycarbonyl-PEG5-sulfonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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t-Butoxycarbonyl-PEG5-sulfonic acid Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
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- Advantage
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