Propargyl-PEG5-CH2CO2-NHS

Product Name: Propargyl-PEG5-CH2CO2-NHS
CAS No.: 1161883-51-7
Chemical Name: Propargyl-PEG5-CH2CO2-NHS
Synonyms: Propargyl-PEG4-CH2COONHS;Propargyl-PEG5-CH2CO2-NHS;Propargyl-PEG4-O-C1-NHS ester;Propargyl-PEG4-CH2CONHS ester;Propargyl-PEG5-CH2COO-NHS ester;Propargyl-PEG5-CH2COOH NHS Ester;2,5-dioxopyrrolidin-1-yl 3,6,9,12,15-pentaoxaoctadec-17-ynoate;3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB03373761
Molecular Formula: C17H25NO9
Formula Weight: 387.38
MOL File: 1161883-51-7.mol

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Propargyl-PEG5-CH2CO2-NHS Property

storage temp.: Storage temp. -20°C
solubility: Soluble in DMSO, DCM, DMF
form: Viscous Liquid
color: Colorless to light brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23812
Product name: Propargyl-PEG5-CH2CO2-NHS
Packaging: 100mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-23812
Product name: Propargyl-PEG5-CH2CO2-NHS
Packaging: 500mg
Price: $680
Updated: 2021/12/16

BroadPharm

Product number: BP-23812
Product name: Propargyl-PEG5-CH2CO2-NHS
Packaging: 1g
Price: $980
Updated: 2021/12/16

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Propargyl-PEG5-CH2CO2-NHS Chemical Properties,Usage,Production

Description

Propargyl-PEG5-CH2CO2-NHS is an amine reactive linker with an alkyne moeity which can react with azide-bearing biomolecules in copper catalyzed Click Chemistry reactions. The PEG units enhance the solubility of the linker in aqueous media.

Uses

Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] Kussrow A, et al. Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scatteringinterferometry. Anal Chem. 2009 Jun 15;81(12):4889-97. DOI:10.1021/ac900569c

Propargyl-PEG5-CH2CO2-NHS Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG5-CH2CO2-NHS Suppliers

China 23 United States 2 Global 25

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1161883-51-7, Propargyl-PEG5-CH2CO2-NHSRelated Search:

2-(prop-2-ynyloxy)acetic acid 2-(2-Propyn-1-yloxy)acetic acid tert-butyl ester Propargyl-PEG5-CH2CO2H Propargyl-PEG5-CH2CO2tBu

Propargyl-PEG5-CH2CO2-NHS

Propargyl-PEG4-O-C1-NHS ester

3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester

Propargyl-PEG4-CH2COONHS

Propargyl-PEG5-CH2COO-NHS ester

Propargyl-PEG5-CH2COOH NHS Ester

2,5-dioxopyrrolidin-1-yl 3,6,9,12,15-pentaoxaoctadec-17-ynoate

Propargyl-PEG4-CH2CONHS ester

1161883-51-7