t-boc-N-amido-PEG9-azide
- Product Name
- t-boc-N-amido-PEG9-azide
- CAS No.
- 2112731-50-5
- Chemical Name
- t-boc-N-amido-PEG9-azide
- Synonyms
- N3-PEG9-NHBoc;Boc-NH-PEG9-azide;BocNH-PEG9-CH2CH2N3;Azido-PEG9-Boc Amine;t-boc-N-amido-PEG9-azide;5,8,11,14,17,20,23,26,29-Nonaoxa-2-azahentriacontanoic acid, 31-azido-, 1,1-dimethylethyl ester;tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
- CBNumber
- CB03373781
- Molecular Formula
- C25H50N4O11
- Formula Weight
- 582.69
- MOL File
- 2112731-50-5.mol
t-boc-N-amido-PEG9-azide Property
- solubility
- Soluble in Water, DMSO, DCM, DMF
N-Bromosuccinimide Price
- Product number
- BP-23555
- Product name
- t-boc-N-amido-PEG9-azide
- Purity
- 96%
- Packaging
- 100mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- BP-23555
- Product name
- t-boc-N-amido-PEG9-azide
- Purity
- 96%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- BP-23555
- Product name
- t-boc-N-amido-PEG9-azide
- Purity
- 96%
- Packaging
- 1g
- Price
- $565
- Updated
- 2021/12/16
- Product number
- 4326309
- Product name
- BocNH-PEG9-CH2CH2N3
- Purity
- min.97%
- Packaging
- 250mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- 4326309
- Product name
- BocNH-PEG9-CH2CH2N3
- Purity
- min.97%
- Packaging
- 1g
- Price
- $565
- Updated
- 2021/12/16
t-boc-N-amido-PEG9-azide Chemical Properties,Usage,Production
Description
t-boc-N-amido-PEG9-azide is a PEG reagent with an azide and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to free the amine.
Uses
Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG9-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-boc-N-amido-PEG9-azide Preparation Products And Raw materials
Raw materials
Preparation Products
t-boc-N-amido-PEG9-azide Suppliers
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View Lastest Price from t-boc-N-amido-PEG9-azide manufacturers
- Product
- Azido-PEG9-NHBoc 2112731-50-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23