Azido-PEG9-t-butyl ester
- Product Name
- Azido-PEG9-t-butyl ester
- CAS No.
- 1818294-43-7
- Chemical Name
- Azido-PEG9-t-butyl ester
- Synonyms
- Azido-PEG9-Boc;CAS_1818294-43-7;Azido-PEG9-COOtBu;Azido-PEG9-tBu Ester;Azido-PEG9-t-butyl ester;Azido-PEG10-t-butyl ester;tert-Butyl 1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate;4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-, 1,1-dimethylethyl ester
- CBNumber
- CB73062374
- Molecular Formula
- C25H49N3O11
- Formula Weight
- 567.68
- MOL File
- 1818294-43-7.mol
Azido-PEG9-t-butyl ester Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BIPG1174
- Product name
- Azido-PEG9-t-butyl ester
- Packaging
- 100mg
- Price
- $449
- Updated
- 2021/12/16
- Product number
- BP-24004
- Product name
- Azido-PEG10-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $995
- Updated
- 2021/12/16
Azido-PEG9-t-butyl ester Chemical Properties,Usage,Production
Description
Azido-PEG9-t-butyl ester is a PEG linker molecule with an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The PEG9 spacer increases solubility in aqueous media.
Uses
Azido-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG9-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG9-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Azido-PEG9-t-butyl ester manufacturers
- Product
- azido-PEG9-t-Butyl ester 1818294-43-7
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-23