Azido-PEG9-t-butyl ester

Product Name: Azido-PEG9-t-butyl ester
CAS No.: 1818294-43-7
Chemical Name: Azido-PEG9-t-butyl ester
Synonyms: Azido-PEG9-Boc;CAS_1818294-43-7;Azido-PEG9-COOtBu;Azido-PEG9-tBu Ester;Azido-PEG9-t-butyl ester;Azido-PEG10-t-butyl ester;tert-Butyl 1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate;4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-, 1,1-dimethylethyl ester
CBNumber: CB73062374
Molecular Formula: C25H49N3O11
Formula Weight: 567.68
MOL File: 1818294-43-7.mol

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Azido-PEG9-t-butyl ester Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific

Product number: BIPG1174
Product name: Azido-PEG9-t-butyl ester
Packaging: 100mg
Price: $449
Updated: 2021/12/16

BroadPharm

Product number: BP-24004
Product name: Azido-PEG10-t-butylester
Purity: 98%
Packaging: 1g
Price: $995
Updated: 2021/12/16

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Azido-PEG9-t-butyl ester Chemical Properties,Usage,Production

Description

Azido-PEG9-t-butyl ester is a PEG linker molecule with an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The PEG9 spacer increases solubility in aqueous media.

Uses

Azido-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG9-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG9-t-butyl ester Preparation Products And Raw materials

Raw materials

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Azido-PEG9-t-butyl ester Suppliers

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View Lastest Price from Azido-PEG9-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG9-t-Butyl ester 1818294-43-7
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-23

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Azido-PEG9-t-butyl ester

Azido-PEG10-t-butyl ester

CAS_1818294-43-7

Azido-PEG9-COOtBu

Azido-PEG9-Boc

Azido-PEG9-tBu Ester

4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-, 1,1-dimethylethyl ester

tert-Butyl 1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate

1818294-43-7

818294-43-7