Azido-PEG11-alcohol
- Product Name
- Azido-PEG11-alcohol
- CAS No.
- 2252392-53-1
- Chemical Name
- Azido-PEG11-alcohol
- Synonyms
- Azido-PEG11-alcohol;PROTAC Linkers,PROTAC,PEG,inhibit,tumor,cancer,AzidoPEG11alcohol,Azido-PEG-11-alcohol,Linker,Azido PEG11 alcohol,Inhibitor
- CBNumber
- CB13134154
- Molecular Formula
- C22H45N3O11
- Formula Weight
- 527.61
- MOL File
- 2252392-53-1.mol
Azido-PEG11-alcohol Property
- solubility
- Soluble in Water, DMSO, DCM, DMF
N-Bromosuccinimide Price
- Product number
- BP-22977
- Product name
- Azido-PEG11-alcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $575
- Updated
- 2021/12/16
Azido-PEG11-alcohol Chemical Properties,Usage,Production
Description
Azido-PEG11-alcohol is a monodisperse linear PEG linker. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG11-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG11-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG11-alcohol Suppliers
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View Lastest Price from Azido-PEG11-alcohol manufacturers
- Product
- azido-PEG11-OH 2252392-53-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23