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BTSA 1

Product Name
BTSA 1
CAS No.
314761-14-3
Chemical Name
BTSA 1
Synonyms
BTSA 1;CS-2853;BTSA 1;BTSA-1;BTSA1 >=98% (HPLC);5-Phenyl-2-(4-phenyl-thiazol-2-yl)-4-(thiazol-2-yl-hydrazono)-2,4-dihydro-pyrazol-3-one;1H-Pyrazole-4,5-dione, 3-phenyl-1-(4-phenyl-2-thiazolyl)-, 4-[2-(2-thiazolyl)hydrazone];5-Phenyl-2-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-2,4-dihydro-3H-pyrazol-3-one;inhibit,FITC-BIM,caspase-3/7,translocation,Bcl-2 Family,viability,Inhibitor,BTSA1,mitochondrial,pharmacologically,BAX,AML,BTSA 1,BTSA-1,SAHBA2,Apoptosis
CBNumber
CB03374627
Molecular Formula
C21H14N6OS2
Formula Weight
430.51
MOL File
314761-14-3.mol
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BTSA 1 Property

Boiling point:
625.2±48.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:53.0(Max Conc. mg/mL);123.11(Max Conc. mM)
pka
6.52±0.40(Predicted)
form 
Solid
color 
Brown to reddish brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot
Product number
CD31005001
Product name
BTSA1
Purity
98%
Packaging
2mg
Price
$86
Updated
2021/12/16
Crysdot
Product number
CD31005001
Product name
BTSA1
Purity
98%
Packaging
5mg
Price
$158
Updated
2021/12/16
Crysdot
Product number
CD31005001
Product name
BTSA1
Purity
98%
Packaging
10mg
Price
$313
Updated
2021/12/16
Crysdot
Product number
CD31005001
Product name
BTSA1
Purity
98%
Packaging
25mg
Price
$514
Updated
2021/12/16
DC Chemicals
Product number
012494
Product name
BTSA1
Packaging
001
Price
$700
Updated
2021/12/16
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BTSA 1 Chemical Properties,Usage,Production

Biological Activity

BTSA1 is a BAX activator that binds to its N-terminal activation site with high affinity and specificity, induces a conformational change in BAX, and causes BAC-mediated apoptosis. It efficiently promotes apoptosis in leukemia cell lines and patient samples without affecting healthy cells.

in vivo

BTSA1 effectively inhibits human acute myeloid leukemia xenografts and enhances host survival without toxic side effects. In mice, it was well tolerated.

target

BTSA 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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BTSA 1 Suppliers

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314761-14-3, BTSA 1Related Search:


  • BTSA 1
  • BTSA 1;BTSA-1
  • 5-Phenyl-2-(4-phenyl-thiazol-2-yl)-4-(thiazol-2-yl-hydrazono)-2,4-dihydro-pyrazol-3-one
  • CS-2853
  • 1H-Pyrazole-4,5-dione, 3-phenyl-1-(4-phenyl-2-thiazolyl)-, 4-[2-(2-thiazolyl)hydrazone]
  • BTSA1 >=98% (HPLC)
  • inhibit,FITC-BIM,caspase-3/7,translocation,Bcl-2 Family,viability,Inhibitor,BTSA1,mitochondrial,pharmacologically,BAX,AML,BTSA 1,BTSA-1,SAHBA2,Apoptosis
  • 5-Phenyl-2-(4-phenylthiazol-2-yl)-4-(2-(thiazol-2-yl)hydrazono)-2,4-dihydro-3H-pyrazol-3-one
  • 314761-14-3
  • C21H14N6OS2
  • API
  • TargetValue
    Bax
    ()