BPV(PIC)
- Product Name
- BPV(PIC)
- CAS No.
- 148556-27-8
- Chemical Name
- BPV(PIC)
- Synonyms
- BPV(PIC);K2 [VO(O2)2C6H4NO2] 2 H2O;bpV(pic) (potassium hydrate);Dipotassium Bisperoxovanadium(pic) dihydrate;DIPOTASSIUM BISPEROXO(PICOLINATO)OXOVANADATE (V);Dipotassium bisperoxo (picolinato) oxovanadate (V) dihydrate
- CBNumber
- CB0345392
- Molecular Formula
- C6H8K2NO9V-3
- Formula Weight
- 367.26712
- MOL File
- 148556-27-8.mol
BPV(PIC) Property
- storage temp.
- -20°C
- solubility
- H2O: soluble20mg/mL, clear
- form
- powder
- color
- faint yellow to dark yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SML0885
- Product name
- bpV(pic)
- Purity
- ≥95% V basis
- Packaging
- 5mg
- Price
- $104
- Updated
- 2024/03/01
- Product number
- SML0885
- Product name
- bpV(pic)
- Purity
- ≥95% V basis
- Packaging
- 25mg
- Price
- $167.6
- Updated
- 2024/03/01
- Product number
- 14434
- Product name
- bpV(pic) (potassium hydrate)
- Purity
- ≥96%
- Packaging
- 5mg
- Price
- $78
- Updated
- 2024/03/01
- Product number
- 14434
- Product name
- bpV(pic) (potassium hydrate)
- Purity
- ≥96%
- Packaging
- 25mg
- Price
- $330
- Updated
- 2024/03/01
- Product number
- V785033
- Product name
- bpV(pic)
- Packaging
- 5mg
- Price
- $70
- Updated
- 2021/12/16
BPV(PIC) Chemical Properties,Usage,Production
Uses
bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.
Uses
bpV(pic) is a potent protein PTP inhibitor.
Biochem/physiol Actions
bpV(pic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for phosphatase and tensin homolog (PTEN), a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(pic) are 31 nM for PTEN compared to 12.7 μM for PTPβ and 61 μM for PTP-1β. bpV(pic) can also act as an insulin mimetic and activate insulin receptor kinase (IRK).
BPV(PIC) Preparation Products And Raw materials
Raw materials
Preparation Products
BPV(PIC) Suppliers
- Tel
- 021-61415566 800-8193336
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- Country
- China
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- China
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- 021-58436166
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- 15002134094
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- China
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- +1-833-552-7181
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- United States
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