Synthesis
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4-NITROBENZHYDRAZIDE

Synthesis
Product Name
4-NITROBENZHYDRAZIDE
CAS No.
636-97-5
Chemical Name
4-NITROBENZHYDRAZIDE
Synonyms
Inhd18;Nsc 9804;AKOS B016226;AKOS BBS-00001033;P-NITROBENZHYDRAZIDE;4-NITROBENZHYDRAZIDE;P-NITROBENZOHYDRAZIDE;4-NITROBENZOHYDRAZIDE;4-Nireobenzoylhydrazine;p-Nitrobenzoylhydrazide
CBNumber
CB0355890
Molecular Formula
C7H7N3O3
Formula Weight
181.15
MOL File
636-97-5.mol
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4-NITROBENZHYDRAZIDE Property

Melting point:
210-214 °C
Boiling point:
292.97°C (rough estimate)
Density 
1.3539 (rough estimate)
refractive index 
1.5860 (estimate)
solubility 
acetone: soluble0.5g/10 mL, clear, yellow
pka
2.77, 11.17(at 25℃)
form 
crystals
color 
Yellow
PH Range
Colorless (8.2) to yellow (9.5)
λmax
267nm
BRN 
519882
Major Application
corrosion inhibitor, disinfectant, cosmetics, paints toothpaste, mouthwash, antifungal agent, inhibit fibrosis, antituberculosis agent
CAS DataBase Reference
636-97-5(CAS DataBase Reference)
EPA Substance Registry System
4-Nitrobenzoylhydrazine (636-97-5)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
36/37/39-26-37/39
WGK Germany 
3
RTECS 
DH5670000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29280000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
N0149
Product name
4-Nitrobenzhydrazide
Packaging
5G
Price
$26
Updated
2025/07/31
TCI Chemical
Product number
N0149
Product name
4-Nitrobenzhydrazide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$79
Updated
2025/07/31
Frontier Specialty Chemicals
Product number
JK432848
Product name
4-Nitrobenzhydrazide
Purity
98%
Packaging
5g
Price
$47
Updated
2021/12/16
AK Scientific
Product number
V7044
Product name
4-Nitrobenzohydrazide
Packaging
5g
Price
$77
Updated
2021/12/16
AK Scientific
Product number
V7044
Product name
4-Nitrobenzohydrazide
Packaging
25g
Price
$137
Updated
2021/12/16
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4-NITROBENZHYDRAZIDE Chemical Properties,Usage,Production

Synthesis

Dissolve 218 g of p-nitrobenzyl acetate in 500 ml of hot methanol, stir, and slowly add 380 g of 15% sodium hydroxide solution. After the addition was completed, it was placed for 5 minutes, and then poured into ice water to precipitate a precipitate. The filtered precipitate was decolorized with activated carbon in hot water, and recrystallized to give p-nitrobenzoicacidhydrazide 110-121 g .

Chemical Properties

yellow crystalline powder

Uses

4-Nitrobenzoic hydrazide has been used as internal standard in determination of isoniazid in human plasma by LC-MS/MS method.

Definition

ChEBI: A C-nitro compound in which the nitro group is substituted into the 4-position of benzohydrazide.

4-NITROBENZHYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-NITROBENZHYDRAZIDE Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
14948
Advantage
58
Jinan Liheng Biotechnology Co., Ltd.
Tel
0531-18763987518 18763987518
Email
levi@lihengpharm.com
Country
China
ProdList
1797
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29784
Advantage
58
Shanghai Baoyang Baoxin Biotechnology Co., LTD
Tel
021-56698539 19921169802
Email
bxsw_sh@163.com
Country
China
ProdList
3917
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
Advantage
58
Tiancheng Chemical (Jiangsu) Co., Ltd
Tel
0512-66387919 18662433356
Email
18662433356@163.com
Country
China
ProdList
10970
Advantage
58
Jiangsu Xinsu New Materials Co., Ltd
Tel
0512-66387919 15251950002
Email
15251950002@163.com
Country
China
ProdList
11046
Advantage
58
Nanxing Chemical (Jiangsu) Co., Ltd
Tel
0512-66387035 18662433356
Email
18662433356@163.com
Country
China
ProdList
10929
Advantage
58
Beijing Jingtu Hengsheng Commerce&Trade Co.,Ltd.
Tel
00-13911456598 13911456598
Email
13911456598@163.cn
Country
China
ProdList
2530
Advantage
58

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