Formylhydrazine
- Product Name
- Formylhydrazine
- CAS No.
- 624-84-0
- Chemical Name
- Formylhydrazine
- Synonyms
- FORMOHYDRAZIDE;FORMIC ACID HYDRAZIDE;FORMIC HYDRAZIDE;Formhydrazide;Formylhydrazide;Formic hydrazine;hydrazinecarboxaldehyde;Formhydrazid;Carbazaldehyde;FORMYLHYDRAZINE
- CBNumber
- CB4446886
- Molecular Formula
- CH4N2O
- Formula Weight
- 60.06
- MOL File
- 624-84-0.mol
Formylhydrazine Property
- Melting point:
- 52-57 °C (lit.)
- Boiling point:
- 90°C/0.7mmHg(lit.)
- Density
- 1.094±0.06 g/cm3(Predicted)
- refractive index
- 1.4840 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- water: soluble2.5%, clear, colorless
- pka
- 13.65±0.20(Predicted)
- form
- Shiny Crystalline Flakes
- color
- White
- Water Solubility
- Soluble
- Sensitive
- Hygroscopic
- BRN
- 635759
- InChIKey
- XZBIXDPGRMLSTC-UHFFFAOYSA-N
- CAS DataBase Reference
- 624-84-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Formic acid hydrazide(624-84-0)
- EPA Substance Registry System
- Hydrazinecarboxaldehyde (624-84-0)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- RTECS
- LQ8615000
- F
- 3-8-10
- TSCA
- Yes
- HS Code
- 29280000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 166375
- Product name
- Formic hydrazide
- Packaging
- 25g
- Price
- $66.2
- Updated
- 2025/07/31
- Product number
- 166375
- Product name
- Formic hydrazide
- Packaging
- 100g
- Price
- $239
- Updated
- 2025/07/31
- Product number
- F0667
- Product name
- Formohydrazide
- Purity
- >97.0%(HPLC)
- Packaging
- 25g
- Price
- $61
- Updated
- 2025/07/31
- Product number
- F0667
- Product name
- Formohydrazide
- Purity
- >97.0%(HPLC)
- Packaging
- 100g
- Price
- $167
- Updated
- 2025/07/31
- Product number
- 452005
- Product name
- Hydrazinecarboxaldehyde
- Packaging
- 5g
- Price
- $312
- Updated
- 2021/12/16
Formylhydrazine Chemical Properties,Usage,Production
Chemical Properties
WHITE SHINY CRYSTALLINE FLAKES
Uses
Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.
Synthesis
109-94-4
624-84-0
a) Preparation of Formylhydrazine: Mix ethyl formate (200 g) with methanol (200 mL) and cool to 0-10°C. Under stirring, slowly add a mixed solution of hydrazine hydrate (138 g) and water (20 mL). The reaction mixture was gradually heated to 55-60°C and stirred continuously at this temperature for 24 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Isopropanol was added to the residue and the mixture was cooled to 0-5°C and stirred for 2 hours. The solid product was collected by filtration, washed with isopropanol and dried to give formylhydrazine. Yield: 140 g.
Purification Methods
Recrystallise it from EtOH and dry it in vacuo. Store below 10o; it may disproportionate on storage to 1,2-diformyl hydrazine and hydrazine. It forms a blue [Cu(CH4N2O)]SO4 salt with CuSO4. [Beilstein 2 H 93, 2 III 127, 2 IV 85.]
References
[1] Chemistry of Heterocyclic Compounds, 2006, vol. 42, # 2, p. 233 - 245
[2] Synthesis, 2006, # 9, p. 1504 - 1512
[3] Chemistry - An Asian Journal, 2012, vol. 7, # 4, p. 715 - 724
[4] Gazzetta Chimica Italiana, 1894, vol. 24 II, p. 225
[5] Journal of pharmaceutical sciences, 1970, vol. 59, # 1, p. 105 - 107
Formylhydrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Formylhydrazine manufacturers
- Product
- Formylhydrazine 624-84-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-25
- Product
- Formic acid hydrazide 624-84-0
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100 tons
- Release date
- 2024-08-15
- Product
- Formylhydrazine 624-84-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-30