General Description Chemical Properties Toxicity (to higher animals) Mechanism of Action Control object and using method Attention
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Tebufenozide

General Description Chemical Properties Toxicity (to higher animals) Mechanism of Action Control object and using method Attention
Product Name
Tebufenozide
CAS No.
112410-23-8
Chemical Name
Tebufenozide
Synonyms
MIMIC;rh5992;RoMdan;CONFIRM;Conform;Confirm(TM);MiMic 240LV;MiMic 700WP;ebufenozide;TEBUFENOZIDE
CBNumber
CB0286635
Molecular Formula
C22H28N2O2
Formula Weight
352.47
MOL File
112410-23-8.mol
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Tebufenozide Property

Melting point:
191°; mp 186-188° (Sundaram, 1081)
Density 
1.074±0.06 g/cm3(Predicted)
vapor pressure 
3 x 10 -6 Pa (25 °C)
storage temp. 
0-6°C
solubility 
Chloroform: Slightly Soluble,Methanol: Slightly Soluble
form 
Solid
Water Solubility 
0.83 mg l-1 (20 °C)
pka
10.89±0.46(Predicted)
color 
White to off-white
BRN 
7822297
InChI
InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)
InChIKey
QYPNKSZPJQQLRK-UHFFFAOYSA-N
SMILES
C(N(C(C)(C)C)NC(=O)C1=CC=C(CC)C=C1)(=O)C1=CC(C)=CC(C)=C1
LogP
4.240 (est)
CAS DataBase Reference
112410-23-8(CAS DataBase Reference)
EPA Substance Registry System
Tebufenozide (112410-23-8)
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Safety

Hazard Codes 
N
Risk Statements 
51/53
Safety Statements 
61
RIDADR 
UN 3077
WGK Germany 
2
HazardClass 
9
PackingGroup 
III
HS Code 
29280000
Hazardous Substances Data
112410-23-8(Hazardous Substances Data)
Toxicity
LD50 orally in rats, mice: >5000 mg/kg; dermally in rats: >5000 mg/kg; LD50 in honey bees (96 hr, contact): >234 mg/bee; LC50 in mallard duck (8-day dietary): >5000 mg/kg; LC50 in rainbow trout (96 hr): 5.7 mg/l (Heller)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
31652
Product name
Tebufenozide
Purity
PESTANAL
Packaging
100mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
24055
Product name
Tebufenozide
Purity
≥95%
Packaging
50mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
24055
Product name
Tebufenozide
Purity
≥95%
Packaging
100mg
Price
$152
Updated
2024/03/01
TRC
Product number
T013200
Product name
Tebufenozide
Packaging
100mg
Price
$135
Updated
2021/12/16
AK Scientific
Product number
G709
Product name
Tebufenozide
Packaging
100mg
Price
$154
Updated
2021/12/16
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Tebufenozide Chemical Properties,Usage,Production

General Description

Tebufenozide is an ecdysone insecticide, which causes the premature molting of insects by interfering with the normal development of insects. It has high insecticidal activity and high selectivity, being effective in treatment of all lepidopteran larvae, caterpillar, diamondback moth and beet armyworm. It has a strong ovicidal activity, being safe to non-target organisms. Tebfenozide has no irritating effect on the eyes and skin without any teratogenic, carcinogenic and mutagenic effects on higher animals, being of high safety to mammals, birds and natural enemies. It is an ideal insecticide during integrated control.

Chemical Properties

Pure white powder, melting point 191 ℃. Slightly soluble in water and organic solvents; stable to light. It is stable at 5 ° C in pH 7 aqueous solution upon light emission.

Toxicity (to higher animals)

Low toxicity

Mechanism of Action

Tebufenozide is a pro-skinning compound that selectively controls lepidopteran larvae by acting in close association with the descorticophilin receptor protein. During its effect, tebufenozide mimics the action of natural insect pest hormone 20-hydroxy-descorticoid, leading to its premature, deadly peeling.

Control object and using method

It can be used to control a variety of lettuce larvae such as cabbage, apples and other crops. It is effective in the treatment of all instar larvae at drug interval of 14d.

  • Control Spodoptera exigua, Spodoptera litura, Spodoptera frugiperda, melon field borer and cabbage budworm; apply in the early larvae emergence, spray 1 500 ~ 2 000 times 20% SC.
  • Control apple leaf roller and peach moth worm, Spray 1000 ~ 2000 times 20% suspension.
  • Control corn borer and bean curl moth; spray 1000 ~ 2000 times 20% suspension.

Attention

  1. This product is toxic to silkworms, should pay attention to be away from the silkworm area.
  2. This product is generally effective against Plutella xylostella and can be mixed with avermectin.
  3. Spray uniformly; ensure that the contact of liquid with parasites.
  4. It is best to apply pesticide in the evening when controlling beet armyworm.

Uses

Synthetic nonsteroidal ecdysone agonist causing premature molting; novel insect growth regulator specific to lepidopteran species. Insecticide.

Uses

Tebufenozide is used to control lepidopterous larvae on rice, fruit, row crops, nut crops, vegetables and vines and in forestry.

Definition

ChEBI: A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.

Hazard

Low toxicity by ingestion, inhalation, and skin contact.

Agricultural Uses

Insecticide, Insect growth regulator: Tebufenozide is an insect growth regulator that interferes with molting of Lepidopteran larvae. It is used on fruitworm, fireworms, false armyworm, gypsy moth, and spanworms, and is applied pre-harvest. Registered for use in EU countries. Registered for use in the U.S.

Trade name

CONFIRM®; MIMIC®; RH-5992®

Metabolic pathway

Oxidation of ethyl and methyl substituents of the phenyl rings of tebufenozide occurs in soils and plants, to give carboxylic acids, alcohols and a ketone.

Degradation

Tebufenozide was stable at 94 °C for 7 days, stable to light in pH 7 aqueous solution (25 °C) and stable in dark sterile water for 30 days (25 °C). The DT50 in natural pond water, in light, was 30 days (25 °C) (PM). It was stable in acidic and neutral buffer solutions. Hydrolysis was marked in alkaline conditions (DT50 203 days, pH 10, 20°C). Tebufenozide was stable in sterilised stream water in the dark but degraded in non-sterile water (DT50 181 days). The insecticide was photodegraded by sunlight (DT50 83 hours, summer 46°N). The results suggest that microbial degradation and photolysis will be the main routes of tebufenozide dissipation in natural aquatic conditions (Sundaram, 1994).

Tebufenozide Preparation Products And Raw materials

Raw materials

Preparation Products

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Tebufenozide Suppliers

Jiangsu Kuaida Agrochemical Co., Ltd
Tel
0513-84415666
Fax
+86-513-84542863 &#12288
Email
kuaida@kuaida.cn
Country
China
ProdList
39
Advantage
42
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
021-58956006 15800617331
Fax
021-58956100
Email
sales4@langchem.com
Country
China
ProdList
204
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
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View Lastest Price from Tebufenozide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Tebufenozide 112410-23-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01
Hebei Yanxi Chemical Co., Ltd.
Product
Tebufenozide 112410-23-8
Price
US $30.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-13
Hebei Fengjia New Material Co., Ltd
Product
Tebufenozide 112410-23-8
Price
US $2.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-09-06

112410-23-8, TebufenozideRelated Search:


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