Description References
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Cyromazine

Description References
Product Name
Cyromazine
CAS No.
66215-27-8
Chemical Name
Cyromazine
Synonyms
CIROMAZIN;CYROMAZIN;N2-CYCLOPROPYL-1,3,5-TRIAZINE-2,4,6-TRIAMINE;ARMOR;neoprex;TRIGARD;NEPOREX;Neoprox;cga72662;ARMOR(R)
CBNumber
CB2120418
Molecular Formula
C6H10N6
Formula Weight
166.18
MOL File
66215-27-8.mol
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Cyromazine Property

Melting point:
223-227 °C (lit.)
Boiling point:
284.39°C (rough estimate)
Density 
1.3196 (rough estimate)
vapor pressure 
4.5 x l0-7 Pa (25 °C)
refractive index 
1.8300 (estimate)
Flash point:
100 °C
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
5.2 (base)
Water Solubility 
13 g l-1 (pH 7.1,25 °C)
form 
Solid
color 
White to Off-White
Merck 
14,2775
BRN 
882879
Stability:
Hygroscopic
InChIKey
LVQDKIWDGQRHTE-UHFFFAOYSA-N
LogP
-0.061 at 25℃
CAS DataBase Reference
66215-27-8(CAS DataBase Reference)
NIST Chemistry Reference
Cyromazine(66215-27-8)
EPA Substance Registry System
Cyromazine (66215-27-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
UN3077 (solid)
WGK Germany 
2
RTECS 
XZ1056500
HS Code 
29336990
Hazardous Substances Data
66215-27-8(Hazardous Substances Data)
Toxicity
LC50 (96-hour) for rainbow trout and carp >100 mg/L and bluegill sunfish >90 mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats 3,387 mg/kg (Hartley and Kidd, 1987)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2899
Product name
Cyromazine
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$172
Updated
2024/03/01
Sigma-Aldrich
Product number
45414
Product name
Cyromazin
Purity
PESTANAL , analytical standard
Packaging
50mg
Price
$90.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1161203
Product name
Cyromazin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$457
Updated
2024/03/01
TCI Chemical
Product number
C2366
Product name
Cyromazine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
C2366
Product name
Cyromazine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$39
Updated
2024/03/01
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Cyromazine Chemical Properties,Usage,Production

Description

Cyromazine is a triazine insect growth regulator that can be used as an insecticide and an acarcide. It is a kind of cyclopropylderivative of melamine, and also belongs to the family of aminotriazines which are compound consisting of an amino group attached to a triazine ring. It has specific activity against dipterous larvae, and has been approved by FDA for being applied to livestock. It is not a kind of cholinesterase inhibitor, and taking effect through affecting the nervous system of the immature larval stage of the insects.

References

https://pubchem.ncbi.nlm.nih.gov/compound/cyromazine#section=Top
https://en.wikipedia.org/wiki/Cyromazine
http://pmep.cce.cornell.edu/profiles/insect-mite/cadusafos-cyromazine/cyromazine/insect-prof-cyromazine.html

Chemical Properties

White crystalline powder. The solubility in water is 11,000 mg/L at 20°C and pH 7.5, and the hydrolysis is not obvious at pH 5-9.

Uses

Cypromazine is a high-efficiency and low-toxicity insecticide. It is mainly used to control leafminer pests, has a good control effect on Liriomyza, and can also be used to control flies.

Application

Cyromazine is an insect growth regulator, used to control fly larvae in livestock and poultry manure. It can be fed directly to livestock or applied directly to fly breeding sites. Cyromazine also exhibits systemic activity and is used as a foliar spray to control leaf miners in vegetables, potatoes, etc., and on mushrooms.

Definition

ChEBI: Cyromazine is a triamino-1,3,5-triazine. It has a role as a triazine insecticide and a mouse metabolite.

Preparation

Cyromazine is prepared by the reaction of cyanuric chloride and cyclopropylamine to obtain 2-Cyclopropylamino-4,6-dichloro-triazepine, and then reacts with ammonia to obtain 2-Cyclopropylamino-4-chloro-6-aminostriazepine, and then reacting with ammonia to produce.

General Description

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine, also known as cyromazine, is an insect growth regulator(IGR) that is commonly used as an insecticide. It undergoes metabolism in plants and animals to form melamine. Surface-enhanced Raman scattering (SERS) spectroscopic study indicates that it interacts with the surface of silver colloid through the lone pair on nitrogen.

Flammability and Explosibility

Not classified

Agricultural Uses

Insecticide (insect growth regulator): As an insect growth regulator, cyromazine is fed to caged poultry and is passed through the chicken, leaving a residue in the manure. The chemical controls the growth of the fly larvae developing in the manure. Used as a foliar spray to control leaf miners in vegetables, mushrooms, potatoes and ornamentals and to control flies on animals.

Trade name

ARMOR®; CITATION; CGA-72662®; LARVADEX®; PATRON®; TRIGARD®; VETRAZIN®

Environmental Fate

Chemical/Physical. Cyromazine will react with mineral acids (e.g., hydrochloric acid, sulfuric acid) forming water-soluble salts

Metabolic pathway

Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1993). The major degradation pathway of cyromazine involves the N-dealkylation of the cyclopropyl moiety to yield melamine. Both cyromazine and melamine are quite stable to biotransformation. Deamination and the formation of N-methylcyromazine were observed as minor pathways.

Degradation

Cyromazine (1) is stable to hydrolysis at pH 5, 7 and 9 and 70 °C for up to 28 days. No degradation of cyromazine was observed when irradiated under mercury vapour lamp (>290 nm) at 25 °C for up to 168 hours.

Cyromazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Cyromazine Suppliers

Hefei TNJ Chemical Industry Co.,Ltd.
Tel
551-65418679 15837135945
Fax
0551-65418697
Email
info@tnjchem.com
Country
China
ProdList
1889
Advantage
62
Jiangxi ruiya pharmaceutical co., LTD
Tel
19170706235
Email
hwp@ruiyapharma.com
Country
China
ProdList
75
Advantage
55
Jinan Wald Chemical Co., Ltd.
Tel
0531-88773586 13210588999
Fax
053188773586
Email
304264064@qq.com
Country
China
ProdList
193
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
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View Lastest Price from Cyromazine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cyromazine 66215-27-8
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%-102%; USP
Supply Ability
1000 KG
Release date
2021-06-04
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Cyromazine 66215-27-8
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10ton
Release date
2024-05-21
Hebei Yanxi Chemical Co., Ltd.
Product
triamine 66215-27-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100tons
Release date
2023-08-11

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