L-xylose
- Product Name
- L-xylose
- CAS No.
- 609-06-3
- Chemical Name
- L-xylose
- Synonyms
- XYLOSE;L-(-)-XYLOSE;(2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal;L-XYL;L-XYLOSE;XYLOSE, L;L-Xylose,99%;laevo-xylose;L-Xylose (9CI);L(-)XYLOSE 99%
- CBNumber
- CB0357344
- Molecular Formula
- C5H10O5
- Formula Weight
- 150.13
- MOL File
- 609-06-3.mol
L-xylose Property
- Melting point:
- 150-152 °C(lit.)
- Boiling point:
- 191.65°C (rough estimate)
- Density
- 1.525
- refractive index
- -20 ° (C=10, H2O)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- H2O: 0.1 g/mL, clear, colorless
- form
- Crystalline Powder
- pka
- 12.46±0.20(Predicted)
- color
- White to off-white
- optical activity
- [α]24/D 18.7°, c = 4 in H2O
- Water Solubility
- within almost transparency
- Sensitive
- Hygroscopic
- BRN
- 1723080
- InChIKey
- SRBFZHDQGSBBOR-VVZXFQNISA-N
- LogP
- -2.390 (est)
- CAS DataBase Reference
- 609-06-3(CAS DataBase Reference)
- EPA Substance Registry System
- L-Xylose (609-06-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- F
- 3-10
- TSCA
- Yes
- HS Code
- 29400000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 851590
- Product name
- L-(?)-Xylose, mixture of anomers
- Purity
- ≥99%
- Packaging
- 5g
- Price
- $29.94
- Updated
- 2024/03/01
- Product number
- 851590
- Product name
- L-(?)-Xylose, mixture of anomers
- Purity
- ≥99%
- Packaging
- 25g
- Price
- $56.6
- Updated
- 2024/03/01
- Product number
- X0021
- Product name
- L-(-)-Xylose
- Purity
- >97.0%(T)
- Packaging
- 5g
- Price
- $67
- Updated
- 2024/03/01
- Product number
- X0021
- Product name
- L-(-)-Xylose
- Purity
- >97.0%(T)
- Packaging
- 25g
- Price
- $267
- Updated
- 2024/03/01
- Product number
- B21622
- Product name
- L-(-)-Xylose, 99%
- Packaging
- 5g
- Price
- $46.65
- Updated
- 2024/03/01
L-xylose Chemical Properties,Usage,Production
Chemical Properties
L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.
Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form.
Uses
L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
Application
l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).
L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007).
Preparation
L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).
Definition
ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.
L-xylose Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-xylose manufacturers
- Product
- L-xylose 609-06-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 500kg/month
- Release date
- 2023-01-05
- Product
- L-XYLOSE 609-06-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- L-XYLOSE 609-06-3
- Price
- US $240.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2018-07-27