ChemicalBook > CAS DataBase List > L-xylose

L-xylose

Product Name
L-xylose
CAS No.
609-06-3
Chemical Name
L-xylose
Synonyms
XYLOSE;L-(-)-XYLOSE;(2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal;L-XYL;L-XYLOSE;XYLOSE, L;L-Xylose,99%;laevo-xylose;L-Xylose (9CI);L(-)XYLOSE 99%
CBNumber
CB0357344
Molecular Formula
C5H10O5
Formula Weight
150.13
MOL File
609-06-3.mol
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L-xylose Property

Melting point:
150-152 °C(lit.)
Boiling point:
191.65°C (rough estimate)
Density 
1.525
refractive index 
-20 ° (C=10, H2O)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
H2O: 0.1 g/mL, clear, colorless
form 
Crystalline Powder
pka
12.46±0.20(Predicted)
color 
White to off-white
optical activity
[α]24/D 18.7°, c = 4 in H2O
Water Solubility 
within almost transparency
Sensitive 
Hygroscopic
BRN 
1723080
InChIKey
SRBFZHDQGSBBOR-VVZXFQNISA-N
LogP
-2.390 (est)
CAS DataBase Reference
609-06-3(CAS DataBase Reference)
EPA Substance Registry System
L-Xylose (609-06-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
3-10
TSCA 
Yes
HS Code 
29400000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
851590
Product name
L-(?)-Xylose, mixture of anomers
Purity
≥99%
Packaging
5g
Price
$29.94
Updated
2024/03/01
Sigma-Aldrich
Product number
851590
Product name
L-(?)-Xylose, mixture of anomers
Purity
≥99%
Packaging
25g
Price
$56.6
Updated
2024/03/01
TCI Chemical
Product number
X0021
Product name
L-(-)-Xylose
Purity
>97.0%(T)
Packaging
5g
Price
$67
Updated
2024/03/01
TCI Chemical
Product number
X0021
Product name
L-(-)-Xylose
Purity
>97.0%(T)
Packaging
25g
Price
$267
Updated
2024/03/01
Alfa Aesar
Product number
B21622
Product name
L-(-)-Xylose, 99%
Packaging
5g
Price
$46.65
Updated
2024/03/01
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L-xylose Chemical Properties,Usage,Production

Chemical Properties

L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.

Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form.

Uses

L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Application

l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).
L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007).

Preparation

L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).

Definition

ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.

L-xylose Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-xylose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-xylose 609-06-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2023-01-05
Hebei Mojin Biotechnology Co., Ltd
Product
L-xylose 609-06-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-22
Zhuozhou Wenxi import and Export Co., Ltd
Product
L-XYLOSE 609-06-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

609-06-3, L-xyloseRelated Search:


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  • XYLOSE
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  • L-(-)-Xylose, 99+%, mixture of anomers
  • L(-)XYLOSE 99%
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  • L-Xylose,99%
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  • L-(-)-Xylose, Mixture of anoMers >=99%
  • (2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal
  • L-(-)-Xylose≥ 98% (TLC)
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