2-Chloro-6-methylaniline

Product Name: 2-Chloro-6-methylaniline
CAS No.: 87-63-8
Chemical Name: 2-Chloro-6-methylaniline
Synonyms: 6-CHLORO-O-TOLUIDINE;6-CHLORO-2-METHYLANILINE;6COT;NSC 60121;oro-6-methyL;TIMTEC-BB SBB004153;6-chloro-o-toluidin;2-Chloro-6-methylani;6-CHLORO-2-TOLUIDINE;6-ChIoro-o-toluidine
CBNumber: CB0361613
Molecular Formula: C7H8ClN
Formula Weight: 141.6
MOL File: 87-63-8.mol

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2-Chloro-6-methylaniline Property

Melting point:: 10-12 °C(lit.)
Boiling point:: 215 °C(lit.)
Density: 1.152 g/mL at 25 °C(lit.)
refractive index: n20/D 1.576(lit.)
Flash point:: 210 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
pka: 2.51±0.10(Predicted)
form: Oil
color: Clear Colourless to Pale Purple
Water Solubility: Immiscible
BRN: 774624
InChIKey: WFNLHDJJZSJARK-UHFFFAOYSA-N
CAS DataBase Reference: 87-63-8(CAS DataBase Reference)
NIST Chemistry Reference: Benzenamine, 2-chloro-6-methyl-(87-63-8)
EPA Substance Registry System: 6-Chloro-2-methylaniline (87-63-8)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36-36/37/39
RIDADR: UN 3429 6.1/PG 3
WGK Germany: 3
RTECS: XU5100000
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29214300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H341Suspected of causing genetic defects

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C51008
Product name: 2-Chloro-6-methylaniline
Purity: 98%
Packaging: 1g
Price: $35.4
Updated: 2023/01/07

TCI Chemical

Product number: A1959
Product name: 2-Chloro-6-methylaniline
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $70
Updated: 2024/03/01

TCI Chemical

Product number: A1959
Product name: 2-Chloro-6-methylaniline
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $205
Updated: 2024/03/01

Alfa Aesar

Product number: L02629
Product name: 2-Chloro-6-methylaniline, 98%
Packaging: 25g
Price: $315.65
Updated: 2024/03/01

Alfa Aesar

Product number: L02629
Product name: 2-Chloro-6-methylaniline, 98%
Packaging: 1g
Price: $37.1
Updated: 2021/12/16

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2-Chloro-6-methylaniline Chemical Properties,Usage,Production

Description

2-chloro-6-methylaniline is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides, and organic synthesis. In the aspects of chemical pharmacy and pesticides, 2-chloro-6-methylaniline can be used as a reaction starting material to participate in the preparation processes of tyrosine kinase inhibitors dasatinib, indazole derivatives with anti-breast cancer activity, 2-methyl-6-chlorophenyl sulfonylurea derivatives with bacteriostatic activity and the like; in the aspect of organic synthesis, 2-chloro-6-methylaniline can introduce chemical groups such as hydrazine, nitro, cyano, halogen (F, Cl, Br), and the like into an aromatic ring through diazotization reaction, thereby participating in wide chemical reactions.

Chemical Properties

clear yellow to red-brown liquid

Chemical Properties

The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.

Uses

2-Chloro-6-methylaniline is a substituted aniline used in the preparation of various pharmaceutical compounds. 2-Chloro-6-methylaniline showed inhibition of the polymerization of vinyl acetate.

Preparation

A preparation method of 2-chloro-6-methylaniline takes 3-chloro-5-methyl-4-nitroaniline as a starting material, water as a solvent, and sulfuric acid as a reactant. Eliminates amino groups through diazotization reaction, reduces by hypophosphorous acid to obtain an intermediate, and finally takes iron powder as reducing nitro groups to prepare the 2-chloro-6-methylaniline through a one-pot reaction.

Potential Exposure

Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.

Shipping

UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials

Incompatibilities

Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.

2-Chloro-6-methylaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-6-methylaniline Suppliers

Americas 1 Belgium 1 Canada 1 China 305 Europe 3 France 2 Germany 8 India 12 Japan 1 Slovakia 2 Switzerland 3 United Kingdom 16 United States 51 Global 406

Changzhou Idea-Works Medical Technology Co., Ltd

Tel: 0519-83879978
Email: sales@ideaworkspharm.com
Country: China
ProdList: 85
Advantage: 62

Yangzhou Prince Chemical Co., Ltd

Tel: 0514-84248359 13328140016
Email: sales@princechem.com
Country: China
ProdList: 99
Advantage: 58

China Synchem Technology Co.,Ltd.

Tel: +86-0552-4929304 +86-18055277008
Fax: +86-552-4928800
Email: sales@cnsynchem.com
Country: China
ProdList: 57
Advantage: 65

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

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View Lastest Price from 2-Chloro-6-methylaniline manufacturers

Suzhou Nordica Biopharma CO.,LTD

Product: 2-Chloro-6-methylaniline 87-63-8
Price: US $0.00-0.00/kg
Min. Order: 0.1kg
Purity: 0.99
Supply Ability: 5 tons
Release date: 2024-11-15

Henan Fengda Chemical Co., Ltd

Product: 2-Chloro-6-methylaniline 87-63-8
Price: US $50.00-1.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: g-kg-tons,free sample is available
Release date: 2024-01-02

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Chloro-6-methylaniline 87-63-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-30

87-63-8, 2-Chloro-6-methylanilineRelated Search:

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87-63-7

Nitrogen Compounds

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C7

Amines

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Anilines, Aromatic Amines and Nitro Compounds

pharmaceutical