2,4,5-TRIFLUOROBENZYL CHLORIDE
- Product Name
- 2,4,5-TRIFLUOROBENZYL CHLORIDE
- CAS No.
- 243139-71-1
- Chemical Name
- 2,4,5-TRIFLUOROBENZYL CHLORIDE
- Synonyms
- Sitagliptin Impurity 70;2,4,5-TRIFLUOROBENZYL CHORIDE;2,4,5-TRIFLUOROBENZYL CHLORIDE;alpha-Chloro-2,4,5-trifluorotoluene;Benzene, 1-(chloromethyl)-2,4,5-trifluoro-;Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI);1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene
- CBNumber
- CB0361981
- Molecular Formula
- C7H4ClF3
- Formula Weight
- 180.55
- MOL File
- 243139-71-1.mol
2,4,5-TRIFLUOROBENZYL CHLORIDE Property
- Boiling point:
- 175℃
- Density
- 1,689 g/cm3
- refractive index
- 1.5050
- Flash point:
- 65°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- clear liquid
- color
- Colorless to Almost colorless
- InChI
- InChI=1S/C7H4ClF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2
- InChIKey
- JMXPOOVDUVHJRO-UHFFFAOYSA-N
- SMILES
- C1(CCl)=CC(F)=C(F)C=C1F
- CAS DataBase Reference
- 243139-71-1(CAS DataBase Reference)
Safety
- Hazard Codes
- C,Xn
- Risk Statements
- 34-36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-36
- RIDADR
- 3265
- Hazard Note
- Corrosive
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234Keep only in original container.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P390Absorb spillage to prevent material damage.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P406Store in corrosive resistant/… container with a resistant inner liner.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T2889
- Product name
- 2,4,5-Trifluorobenzyl Chloride
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $54
- Updated
- 2024/03/01
- Product number
- T2889
- Product name
- 2,4,5-Trifluorobenzyl Chloride
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $188
- Updated
- 2024/03/01
- Product number
- B20470
- Product name
- 2,4,5-Trifluorobenzyl chloride, 97%
- Packaging
- 1g
- Price
- $43.2
- Updated
- 2023/06/20
- Product number
- B20470
- Product name
- 2,4,5-Trifluorobenzyl chloride, 97%
- Packaging
- 5g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- T899188
- Product name
- 2,4,5-Trifluorobenzyl Chloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
2,4,5-TRIFLUOROBENZYL CHLORIDE Chemical Properties,Usage,Production
Chemical Properties
Colorless to Almost colorless clear liquid.
Uses
2,4,5-Trifluorobenzyl chloride is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor that decreases in glucagon to improve control of blood sugar used for the treatment of type 1 diabetes, 79% of the dose excreted in the urine.
Uses
2,4,5-Trifluorobenzyl chloride is a useful research chemical.
Synthesis
On the four-neck flask, install a stirrer, a thermometer, a chlorine gas pipe and a reflux condenser. The reflux condenser is connected to the HCl absorption system, and a light source is installed near the flask.Add 146.0g 2,4,5-trifluorotoluene and 3.0g azobisisobutyronitrile into the reaction flask, stir and heat, and when the temperature rises to 110°C, add dry chlorine gas, and Using GC tracking, after about 3h of chlorine gas, stop the halogenating agent chlorine gas, cool the reactant, wash it with water to neutrality, dry and distill under reduced pressure to obtain 2,4,5-trifluorobenzyl chloride.
2,4,5-TRIFLUOROBENZYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4,5-TRIFLUOROBENZYL CHLORIDE manufacturers
- Product
- 2,4,5-TRIFLUOROBENZYL CHLORIDE 243139-71-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-17
- Product
- 2,4,5-TRIFLUOROBENZYL CHLORIDE 243139-71-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2022-11-17
- Product
- 2,4,5-TRIFLUOROBENZYL CHLORIDE 243139-71-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11