ChemicalBook > CAS DataBase List > (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
- Product Name
- (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
- CAS No.
- 2088771-61-1
- Chemical Name
- (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione
- Synonyms
- Impurity FP-B;Sitagliptin-17;Sitagliptin Impurity 20;Sitagliptin Impurity FP-B;Sitagliptin FP Impurity B;Sitagliptin Triazecine Impurity;(R)-Sitagliptin Tablets EP Impurity FP-B;(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl);Sitagliptin FP Impurity B/ Sitagliptin Triazecine Analog;(R)-Sitagliptin Tablets EP Impurity FP-B ((R)-Sitagliptin Triazecine Analog)
- CBNumber
- CB23371367
- Molecular Formula
- C16H13F6N5O2
- Formula Weight
- 421.3
- MOL File
- 2088771-61-1.mol
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(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Property
- Melting point:
- >189°C (dec.)
- Density
- 1.67±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 12.02±0.40(Predicted)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C16H13F6N5O2/c17-9-6-11(19)10(18)4-7(9)3-8-5-12(28)23-1-2-27-13(14(29)24-8)25-26-15(27)16(20,21)22/h4,6,8H,1-3,5H2,(H,23,28)(H,24,29)/t8-/m1/s1
- InChIKey
- CJUCSNDPMOGZTM-MRVPVSSYSA-N
- SMILES
- N1[C@H](CC2=CC(F)=C(F)C=C2F)CC(=O)NCCN2C(C(F)(F)F)=NN=C2C1=O
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(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Chemical Properties,Usage,Production
Uses
(10R)-Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.
(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Preparation Products And Raw materials
Raw materials
Preparation Products
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(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Suppliers
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2088771-61-1, (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dioneRelated Search:
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