Sitagliptin N-Boc IMpurity

Product Name: Sitagliptin N-Boc IMpurity
CAS No.: 486460-23-5
Chemical Name: Sitagliptin N-Boc IMpurity
Synonyms: Sitagliptin-3;Boc-Sitagliptin;N-Boc-Sitagliptin;Sitagliptin N-Boc;Sitagliptin Impurity 56;Phenol,3-fluoro-8-iodo-;Sitagliptin Impurity 03;Sitagliptin N-Boc IMpurity;Sitagliptin EP Impurity 16;Sitagliptin N-Boc impurities
CBNumber: CB42675705
Molecular Formula: C21H23F6N5O3
Formula Weight: 507.43
MOL File: 486460-23-5.mol

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Sitagliptin N-Boc IMpurity Property

Melting point:: 188-191 °C(Solv: toluene (108-88-3))
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly, Heated), DMSO (Slightly), Ethyl Acetate (Slightly)
pka: 11.60±0.46(Predicted)
form: Solid
color: White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B667500
Product name: N-Boc-Sitagliptin
Packaging: 25mg
Price: $180
Updated: 2021/12/16

Alichem

Product number: 486460235
Product name: (R)-tert-Butyl(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate
Packaging: 5g
Price: $816
Updated: 2021/12/16

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Sitagliptin N-Boc IMpurity Chemical Properties,Usage,Production

Uses

N-Boc-Sitagliptin is the N-Boc protected derivative of Sitagliptin (S490990), a dipeptidyl peptidase-4 inhibitor that is used for glycemic control for patients with type 2 diabetes.

Sitagliptin N-Boc IMpurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Sitagliptin N-Boc IMpurity Suppliers

China 87 India 9 United States 6 Global 102

J & K SCIENTIFIC LTD.

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486460-23-5, Sitagliptin N-Boc IMpurityRelated Search:

1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin Impurity 28 Sitagliptin phosphate monohydrate Sitagliptin N-Phoshate IMpurity Sitagliptin Impurity 27 Sitagliptin Sitagliptin Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one Sitagliptin Impurity 14 (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid 2,4,5-Trifluorobenzaldehyde BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID Sitagliptin Impurity 35 Sitagliptin impurity H HCl Sitagliptin Impurity 31 Sitagliptin N-Sulfate

Sitagliptin N-Boc IMpurity

Boc-Sitagliptin

tert-Butyl N-[(2R)-4-oxo-4-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamate

Sitagliptin N-Boc

N-Boc-Sitagliptin

(R)-tert-Butyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate

tert-butyl (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4] triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan- 2-yl)carbamate

Sitagliptin Impurity 56

Sitagliptin impurity 10/Sitagliptin N-Boc Impurity/tert-butyl (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate

(R)-tert-butyl (4-oxo-4-(3-(trifluoromethyl)-

Sitagliptin-3

Sitagliptin Impurity 18 (Sitagliptin N-Boc Impurity)

Carbamic acid,[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-, 1,1-dimethylethylester

Sitagliptin N-Boc impurities

Carbamic acid, N-[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-, 1,1-dimethylethyl ester

tert-butyl N-[(2R)-4-oxo-4-[3-(trifluoromethyl)-5H,6H,7H,8H-[ 1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorop henyl)butan-2-yl]carbamate

Sitagliptin EP Impurity 16

Carbamic acid,[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4...

Sitagliptin phosphate impurity 7

Phenol,3-fluoro-8-iodo-

Sitagliptin Impurity 03

Sitagliptin Impurity 18 tert-butyl (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5- trifluorophenyl)butan-2-yl)carbamate

(R)-[3-Oxo-1-(2,4,5-trifluoro-benzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-propyl]-carbamic acid tert-butyl ester

486460-23-5