Sitagliptin EP Impurity C

Product Name: Sitagliptin EP Impurity C
CAS No.: 945261-48-3
Chemical Name: Sitagliptin EP Impurity C
Synonyms: Sitagliptin-6;Sitagliptin Impurity 07;2,4-Difluoro Sitagliptin;Sitagliptin EP Impurity C;Sitagliptin Defuoro IMpurity 2;Sitagliptin phosphate impurity E;Sitagliptin 2,4-Difluoro Analogue;(R)-3-amino-4-(2,4-difluorophenyl);Sitagliptin Phosphate Monohydrate EP Impurity C;Sitagliptin Impurity 16 (Sitagliptin EP Impurity C)
CBNumber: CB93154994
Molecular Formula: C16H16F5N5O
Formula Weight: 389.32
MOL File: 945261-48-3.mol

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Sitagliptin EP Impurity C Property

Boiling point:: 531.8±60.0 °C(Predicted)
Density: 1.56±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 7.79±0.10(Predicted)
Major Application: pharmaceutical

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
STOT RE 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: A577556
Product name: 5-DesfluoroSitagliptin
Packaging: 50mg
Price: $1320
Updated: 2021/12/16

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Sitagliptin EP Impurity C Chemical Properties,Usage,Production

Uses

5-Desfluoro Sitagliptin is a Sitagliptin impurity (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin EP Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

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Sitagliptin EP Impurity C Suppliers

China 49 India 2 United States 3 Global 54

Adamas Reagent, Ltd.

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945261-48-3, Sitagliptin EP Impurity CRelated Search:

Sitagliptin Impurity 28 Sitagliptin DeaMino IMpurity 1 rac-Sitagliptin EP Impurity B HCl 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Sitagliptin Impurity 31 (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin phosphate 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- Sitagliptin Sitagliptin N-Phoshate IMpurity Sitagliptin Impurity 27 Sitagliptin impurity H HCl Sitagliptin Impurity 1 rac-Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 3 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate

Sitagliptin Defuoro IMpurity 2

Sitagliptin impurity 40/5-Desfluoro Sitagliptin/(R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6- dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one

Sitagliptin-6

(R)-3-amino-4-(2,4-difluorophenyl)

1-Butanone, 3-amino-4-(2,4-difluorophenyl)-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-, (3R)-

Sitagliptin Impurity 16 (Sitagliptin EP Impurity C)

Sitagliptin phosphate impurity E

Sitagliptin 2,4-Difluoro Analogue

(R)-7-[3-Amino-1-oxo-4-(2,4-difluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine

(R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one? (Sitagliptin Impurity）

Sitagliptin Impurity 07

Sitagliptin EP Impurity C

Sitagliptin Phosphate Monohydrate EP Impurity C

(3R)-3-Amino-4-(2,4-difluorophenyl)-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3- a]pyrazin-7(8H)-yl]butan-1-one

2,4-Difluoro Sitagliptin

945261-48-3