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Sitagliptin EP Impurity C

Product Name
Sitagliptin EP Impurity C
CAS No.
945261-48-3
Chemical Name
Sitagliptin EP Impurity C
Synonyms
Sitagliptin-6;Sitagliptin Impurity 07;Sitagliptin EP Impurity C;Sitagliptin Defuoro IMpurity 2;Sitagliptin phosphate impurity E;Sitagliptin 2,4-Difluoro Analogue;(R)-3-amino-4-(2,4-difluorophenyl);Sitagliptin Phosphate Monohydrate EP Impurity C;Sitagliptin Impurity 16 (Sitagliptin EP Impurity C);(R)-7-[3-Amino-1-oxo-4-(2,4-difluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
CBNumber
CB93154994
Molecular Formula
C16H16F5N5O
Formula Weight
389.32
MOL File
945261-48-3.mol
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Sitagliptin EP Impurity C Property

Boiling point:
531.8±60.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
pka
7.79±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A577556
Product name
5-DesfluoroSitagliptin
Packaging
50mg
Price
$1320
Updated
2021/12/16
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Sitagliptin EP Impurity C Chemical Properties,Usage,Production

Uses

5-Desfluoro Sitagliptin is a Sitagliptin impurity (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin EP Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

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945261-48-3, Sitagliptin EP Impurity CRelated Search:

Sitagliptin Impurity 28 Sitagliptin DeaMino IMpurity 1 rac-Sitagliptin EP Impurity B HCl 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Sitagliptin Impurity 31 (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin phosphate 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- Sitagliptin Sitagliptin N-Phoshate IMpurity Sitagliptin Impurity 27 Sitagliptin impurity H HCl Sitagliptin Impurity 1 rac-Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 3 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate

  • Sitagliptin Defuoro IMpurity 2
  • Sitagliptin impurity 40/5-Desfluoro Sitagliptin/(R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6- dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
  • Sitagliptin-6
  • (R)-3-amino-4-(2,4-difluorophenyl)
  • 1-Butanone, 3-amino-4-(2,4-difluorophenyl)-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-, (3R)-
  • Sitagliptin Impurity 16 (Sitagliptin EP Impurity C)
  • Sitagliptin phosphate impurity E
  • Sitagliptin 2,4-Difluoro Analogue
  • (R)-7-[3-Amino-1-oxo-4-(2,4-difluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
  • (R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one? (Sitagliptin Impurity）
  • Sitagliptin Impurity 07
  • Sitagliptin EP Impurity C
  • Sitagliptin Phosphate Monohydrate EP Impurity C
  • (3R)-3-Amino-4-(2,4-difluorophenyl)-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3- a]pyrazin-7(8H)-yl]butan-1-one
  • 945261-48-3