1-BROMO-2-BUTYNE

ChemicalBook > CAS DataBase List > 1-BROMO-2-BUTYNE

Product Name: 1-BROMO-2-BUTYNE
CAS No.: 3355-28-0
Chemical Name: 1-BROMO-2-BUTYNE
Synonyms: 1-Bromobut-2-yne;2-BUTYNYL BROMIDE;1-Bromobut-2-butyne;1-Brom-2-Butin;Linagliptin INT4;1-BROMO-2-BUTYNE;1-broMo -2-Ding Que;1-Bromobut-2-yne 95%;1-Bromo-2-butyne,98%;1-BROMO-2-BUTYNE 98%
CBNumber: CB0363349
Molecular Formula: C4H5Br
Formula Weight: 132.99
MOL File: 3355-28-0.mol

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1-BROMO-2-BUTYNE Property

Boiling point:: 40-41 °C/20 mmHg (lit.)
Density: 1.519 g/mL at 25 °C (lit.)
refractive index: n20/D 1.508(lit.)
Flash point:: 97 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Miscible with acetonitrile.
form: Liquid
Specific Gravity: 1.519
color: Clear pale yellow-greenish
BRN: 605306
InChIKey: LNNXOEHOXSYWLD-UHFFFAOYSA-N
CAS DataBase Reference: 3355-28-0(CAS DataBase Reference)

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Safety

Risk Statements: 10
Safety Statements: 16-24/25
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
F: 10-23
HazardClass: 3
PackingGroup: III
HS Code: 29033990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 427292
Product name: 1-Bromo-2-butyne
Purity: 99%
Packaging: 1g
Price: $31.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 427292
Product name: 1-Bromo-2-butyne
Purity: 99%
Packaging: 5g
Price: $145
Updated: 2024/03/01

TCI Chemical

Product number: B2190
Product name: 1-Bromo-2-butyne
Purity: >96.0%(GC)
Packaging: 1g
Price: $38
Updated: 2024/03/01

TCI Chemical

Product number: B2190
Product name: 1-Bromo-2-butyne
Purity: >96.0%(GC)
Packaging: 5g
Price: $104
Updated: 2024/03/01

Alfa Aesar

Product number: L20134
Product name: 1-Bromo-2-butyne, 98%
Packaging: 5g
Price: $130
Updated: 2024/03/01

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1-BROMO-2-BUTYNE Chemical Properties,Usage,Production

Chemical Properties

Clear pale yellow-greenish liquid

Uses

1-Bromo-2-butyne is used in the preparation of six to eight annulated ring compounds in reaction with indoles and pseudopterane (+/-)-Kallolide B, which is a marine natural product. Further, it acts as a precursor in the preparation of axially chiral teranyl compounds, alkylation of L-tryptophan methyl ester, 4-butynyloxybenzene sulfonyl chloride and mono-propargylated diene derivative. In addition to this, it is also used in the synthesis of isopropylbut-2-ynylamine, allenylcyclobutanol derivatives, allyl-[4-(but-2-ynyloxy)phenyl]sulfane, allenylindium and axially chiral teranyl compounds.

Preparation

1-bromo-2-butyne is obtained by reacting 2-butyn-1-ol and organic solvent, pyridine.First react bromoethane with metal magnesium in THF to prepare Grignard reagent, then add paraformaldehyde to Grignard reagent for Grignard reaction, separate and recover after Grignard reaction 2-butyn-1-ol, then mix 2-butyn-1-ol with organic solvent and pyridine, add phosphorus tribromide dropwise for bromination reaction, separate and recover the product after bromination reaction.

General Description

1-Bromo-2-butyne is a propargyl bromide derivative. It is one of the constitutional isomer of bromo butyne. Its Br-loss threshold photoionization breakdown diagram has been analyzed to derive dissociative photoionization thresholds to C₄H₅⁺ production. It participates in the preparation of linagliptin.

1-BROMO-2-BUTYNE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-BROMO-2-BUTYNE manufacturers

Hebei Dangtong Import and export Co LTD

Product: 1-BROMO-2-BUTYNE 3355-28-0
Price: US $30.00-20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20Tons
Release date: 2023-10-10

PNP Biotech Co. Ltd

Product: 1-bromo-2-butyne 3355-28-0
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%-99%
Supply Ability: Inquiry
Release date: 2022-10-19

Henan Fengda Chemical Co., Ltd

Product: 1-BROMO-2-BUTYNE 3355-28-0
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

3355-28-0, 1-BROMO-2-BUTYNERelated Search:

Levetiracetam Lercanidipine bamboo flavone Adapalene Rivaroxaban 2-Butyne 1-Bromo-3-butyne,4-BROMO-1-BUTYNE 1-Bromo-1-butyne 1-BROMO-2-BUTYNE 1-BROMO-2-PENTYNE 1,4-DIBROMO-2-BUTYNE 1-(3-BROMO-1-PROPYNYL)NAPHTHALENE 1-BROMO-2-OCTYNE 2-Bromo-3-Butyne 2-Methyl-4-bromo-3-butyne-2-ol 3-Bromo-1-butyne 2-BROMO-3-HEXYNE 1-(3-BROMOPROP-1-YNYL)-3,5-DI(TRIFLUOROMETHYL)BENZENE

1-BROMO-2-BUTYNE

2-BUTYNYL BROMIDE

1-Bromobut-2-yne 95%

1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%1-BROMO-2-BUTYNE, 98%

1-BROMO-2-BUTYNE 98%

1-Bromo-2-butyne,98%

But-2-yn-1-yl bromide

1-broMo -2-Ding Que

1-BroMo-2-butyne, 96.0%(GC)

1-Bromobut-2-yne

Linagliptin INT4

1-Bromo-2-butyne (Linagliptin)

1-BROMO-2-BUTYNE, 2-BUTYNYL BROMIDE

1-Bromobut-2-butyne

1-Bromo-2-butyne &gt

1-BROMO-2-BUTYNE ISO 9001：2015 REACH

Linagliptin intermediates，1-bromo-2-butyne

1-Brom-2-Butin

Rilpivirine Impurity 18

3355-28-0

2563355-28-0

CH3CCCH2Br

Br1C4H5

CH3C8801CCH2Br

C4H5Br

Organic Building Blocks

Halogenated Hydrocarbons

Acetylenes

Functionalized Acetylenes

Alkynyl

Building Blocks

Intermediates

Acetylenes

Functionalized Acetylenes

Alkynyl

Halogenated Hydrocarbons

Organic Building Blocks