FARNESYLPYROPHOSPHATE

Product Name: FARNESYLPYROPHOSPHATE
CAS No.: 13058-04-3
Chemical Name: FARNESYLPYROPHOSPHATE
Synonyms: FPP;trans, trans-farnesyl diphosphate;FARNESYL PYROPHOSPHATE AMMONIUM SALT;FPP 3NH3;FPP 3NH4;FARNESYL-PP;FARNESYLDIPHOSPHATE;FARNESYLPYROPHOSPHATE;FARNESYL DIPHOSPHATE-TA;(E,E)-farnesyl diphosphate
CBNumber: CB0378488
Molecular Formula: C15H28O7P2
Formula Weight: 382.33
MOL File: 13058-04-3.mol

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FARNESYLPYROPHOSPHATE Property

Melting point:: >107°C (dec.)
Boiling point:: 533.8±60.0 °C(Predicted)
Density: 1.233±0.06 g/cm3(Predicted)
Flash point:: 11 °C
storage temp.: -20°C
solubility: Methanol (Slightly, Sonicated), Water (Slightly)
form: methanol:ammonia solution
pka: 1.07±0.50(Predicted)
color: White to Brown
Stability:: Hygroscopic, Light Sensitive, Temperature Sensitive

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45
RIDADR: UN 1230 3/PG 2
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F6892
Product name: Farnesyl pyrophosphate ammonium salt
Purity: methanol:ammonia solution, ≥95% (TLC)
Packaging: 1vial
Price: $105
Updated: 2024/03/01

Sigma-Aldrich

Product number: F6892
Product name: Farnesyl pyrophosphate ammonium salt
Purity: methanol:ammonia solution, ≥95% (TLC)
Packaging: 5vials
Price: $363
Updated: 2024/03/01

Usbiological

Product number: 276173
Product name: Farnesyl pyrophosphate triammonium salt
Packaging: 1mg
Price: $698
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BIO0000460
Product name: FARNESYL PYROPHOSPHATE AMMONIUM SALT
Purity: 95.00%
Packaging: 5MG
Price: $501.48
Updated: 2021/12/16

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FARNESYLPYROPHOSPHATE Chemical Properties,Usage,Production

Uses

Farnesyl pyrophosphate ammonium salt has been used:

as a prenylation agonist in human osteogenic sarcoma cells in collagen-based cell invasion assays
in the prenylation of the hepatocyte growth factor (HGF) in human umbilical vein endothelial cells (HUVECs)
as a substrate in prenyltransferases assay in diatom Haslea ostrearia

Definition

ChEBI: 2-trans,6-trans-farnesyl diphosphate is the trans,trans-stereoisomer of farnesyl diphosphate. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a 2-trans,6-trans-farnesyl diphosphate(3-).

General Description

Farnesyl pyrophosphate is a 15-carbon isoprenoid synthesized from geranyl pyrophosphate (GPP) by the action of enzyme farnesyl pyrophosphate synthase (FPPS).

Biochem/physiol Actions

Farnesyl pyrophosphate (FPP) is the precursor for the biosynthesis of cholesterol, ubiquinone and dolicol. It is part of the intracellular mevalonate pathway. FPP is essential for cell survival and is used for prenylation of several low molecular mass G proteins, including Ras. Inhibition of prenylation results in loss of oncogenic potential of Ras proteins. Inhibition of prenylation may serve as therapeutic potential for management of synaptic plasticity and Alzheimer′s disease.

Purification Methods

Purify the pyrophosphate by chromatography on Whatman No3 MM paper in a system of isopropanol-isobutanol/ammonia/water (40:20:1:30) (v/v). Store it as the Li or NH4 salt at 0o. See geranylgeranyl pyrophosphate below.

FARNESYLPYROPHOSPHATE Preparation Products And Raw materials

Raw materials

Preparation Products

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FARNESYLPYROPHOSPHATE Suppliers

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13058-04-3, FARNESYLPYROPHOSPHATERelated Search:

farnesylpyrophosphate cyclase FARNESYLPYROPHOSPHATE OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT, [1-3H] Geranylgeranyl pyrophosphate TRANS-GERANYLGERANYL-PYROPHOSPHATE, [1-3H] TRIAMMONIUM SALT FPP [1-3H] ALL TRANS-3,7,11,15-TETRAMETHYL-2,6,10,14-HEXADECATETRAENYL TRIPHOSPHATE AMMONIUM SALT 3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-YL TRIPHOSPHATE AMMONIUM SALT TRANS, TRANS FARNESYL TRIPHOSPHATE, TRIAMMONIUM SALT, [1,2-14C] FARNESYL PYROPHOSPHATE-[1-3H(N)] TRIAMMONIUM SALT ALL TRANS GERANYL GERANYL PYROPHOSPHATE, [1-3H], TRIAMMONIUM SALT HEXAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT TRANS, TRANS FARNESYL TRIPHOSPHATE, TETRAAMMONIUM SALT, [1-3H]

FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT SOLUTION

FPP, 3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt

(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-triene-1-ol diphosphoric acid

(E,E)-Farnesyl pyrophosphate

3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE

3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE 3NH3

3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE AMMONIUM SALT

FARNESYL PYROPHOSPHATE AMMONIUM SALT

FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT

FARNESYLPYROPHOSPHATE

FARNESYL DIPHOSPHATE-TA

FPP

FPP 3NH3

FPP 3NH4

farnesyl pyrophosphate ammonium*200 ug/vial

Diphosphoric acid α-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester

(E,E)-farnesyl diphosphate

2-trans,6-trans-farnesyl diphosphate

all-trans-farnesyl diphosphate

FARNESYL-PP

trans, trans-farnesyl diphosphate

Farnesyl pyrophosphate ammonium salt, in ethanol

FARNESYL PYROPHOSPHATE AMMONIUM 200

TRANS, TRANS FARNESYL PYROPHOSPHATE TRIAMMONIUM SALT

3,7,11-trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt

[hydroxy-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]phosphoryl]oxyphosphonic acid

FARNESYLDIPHOSPHATE

Diphosphoric acid, P-(3,7,11-trimethyl-2,6,10-dodecatrien-1-yl) ester

Farnesyl pyrophosphate ammonium salt methanol:ammonia solution

13058-04-3

C15H28O7P2

C15H37N3O7P2

G Protein Function

G Proteins and Cyclic Nucleotides

Post-translational Modification

Cell Signaling and Neuroscience

Cell Biology

BioChemical