ChemicalBook > CAS DataBase List > 4-Methylphthalic anhydride

4-Methylphthalic anhydride

Uses

Product Name: 4-Methylphthalic anhydride
CAS No.: 19438-61-0
Chemical Name: 4-Methylphthalic anhydride
Synonyms: 5-METHYLISOBENZOFURAN-1,3-DIONE;Ethyl-2-benzofuran;4-Methylphthalic;4-Methylphthalic anh;Resorcinol dibenzoate;4-Methylphalic Anhydride;4-METHYLPHTHALIC ANHYDRIDE;4-MethylphthalicAnhydride>5-methyl-3-isobenzofurandione;4-Methylphthalic anhydride,96%
CBNumber: CB0378529
Molecular Formula: C9H6O3
Formula Weight: 162.14
MOL File: 19438-61-0.mol

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4-Methylphthalic anhydride Property

Melting point:: 90-92 °C(lit.)
Boiling point:: 295 °C(lit.)
Density: 1.2599 (rough estimate)
refractive index: 1.5380 (estimate)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: Flakes or Crystalline Powder
color: White to yellow-orange
Water Solubility: insoluble
InChI: InChI=1S/C9H6O3/c1-5-2-3-6-7(4-5)9(11)12-8(6)10/h2-4H,1H3
InChIKey: ZOXBWJMCXHTKNU-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=C(C)C=C2)C(=O)O1
CAS DataBase Reference: 19438-61-0(CAS DataBase Reference)
NIST Chemistry Reference: 4-Methylphthalic anhydride(19438-61-0)
EPA Substance Registry System: 1,3-Isobenzofurandione, 5-methyl- (19438-61-0)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36-36/37/39
WGK Germany: 3
HS Code: 29173990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M0559
Product name: 4-Methylphthalic Anhydride
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $55
Updated: 2025/07/31

TCI Chemical

Product number: M0559
Product name: 4-Methylphthalic Anhydride
Purity: >98.0%(GC)(T)
Packaging: 500g
Price: $391
Updated: 2025/07/31

Apolloscientific

Product number: OR919135
Product name: 4-Methylphthalic Anhydride
Purity: 95%
Packaging: 100g
Price: $189
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2H26-1-0K
Product name: 4-Methylphthalic Anhydride
Purity: 95%
Packaging: 100g
Price: $208
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK462717
Product name: 4-Methylphthalic Anhydride
Purity: 98%
Packaging: 25g
Price: $39
Updated: 2021/12/16

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4-Methylphthalic anhydride Chemical Properties,Usage,Production

Uses

4-Methylphthalic anhydride (4-MPA) is mainly used as an important intermediate in the synthesis of herbicides, especially several cereal herbicides, and can also be used as an intermediate in the synthesis of dyes.

Chemical Properties

white to yellow-orange flakes or

Synthesis

4316-23-8

19438-61-0

The general procedure for the synthesis of 5-methylisobenzofuran-1,3-dione from 4-methylphthalic acid was as follows: 10.0 g of 4-methylphthalic acid and a solvent mixture consisting of 20 mL of N,N-dimethylacetamide, 100 mL of chlorobenzene, and 40 mL of toluene were added to a 300 mL three-necked flask at room temperature and under nitrogen protection. The reaction mixture was heated to 111 °C and the reaction was stirred at this temperature for 10 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting crude product was washed with toluene and dispersed to give 3.6 g of 4-methylphthalic anhydride.

References

[1] Organic Letters, 2010, vol. 12, # 21, p. 4796 - 4799
[2] Monatshefte fuer Chemie, 1891, vol. 12, p. 626
[3] Patent: US2016/376285, 2016, A1. Location in patent: Paragraph 0121

4-Methylphthalic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Methylphthalic anhydride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Methylphthalic anhydride 19438-61-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 4-Methylphthalic anhydride 19438-61-0
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-12

19438-61-0, 4-Methylphthalic anhydrideRelated Search:

Methylhexahydrophthalic anhydride Trifluoromethanesulfonic anhydride Succinic anhydride 3,3',4,4'-Biphenyltetracarboxylic dianhydride Methyl tetrahydrophthalic anhydride CIS-BUTENEDIOIC ANHYDRIDE cis-1,2,3,6-Tetrahydrophthalic anhydride Isatoic Anhydride Glutaric anhydride Phthalic anhydride Resorcinol 3,4-Dimethylaniline 2,4-Dimethyl aniline 4-METHACRYLOXYETHYL TRIMELLITIC ANHYDRIDE Trimellitic Anhydride 4-tert-Butylphthalic anhydride TETRAPHENYLPHTHALIC ANHYDRIDE Acetic anhydride

1,3-Isobenzofurandione, 5-methyl-

5-Methyl-2-benzofuran-1,3-dione

5-methyl-3-isobenzofurandione

4-METHYLPHTHALIC ANHYDRIDE

4-Methylphalic Anhydride

4-METHYLPHTHALIC ANHYDRIDE 95+%

Ethyl-2-benzofuran

5-Methyl-1,3-isobenzofurandione

4-Methylphthalic anhydride,96%

4-Methylphthalic anh

4-Methylphthalic anhydride, 96% 25GR

4-Methylphthalic anhydride, 96% 5GR

4-Methylphthalic anhydride 95%

4-Methylphthalic Anhydride, 98.0%(GC&T

Resorcinol dibenzoate

5-METHYLISOBENZOFURAN-1,3-DIONE

4-MethylphthalicAnhydride&gt

4-Methylphthalic

19438-61-0

19436-61-0

Phthalic Acids, Esters and Derivatives

Organics

Diels-Alder Adducts

Anhydride Monomers

Monomers

Polymer Science